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[177Lu]Lu-dota-tate versus sunitinib in patients with metastatic progressive neuroendocrine tumours of the pancreas (OCLURANDOM): a randomised, controlled, phase 2 trial.

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Title: [177Lu]Lu-dota-tate versus sunitinib in patients with metastatic progressive neuroendocrine tumours of the pancreas (OCLURANDOM): a randomised, controlled, phase 2 trial.
Authors: Baudin E; Department of Imaging, Endocrine Oncology Unit, Gustave Roussy, University Paris Saclay, Villejuif, France. Electronic address: eric.baudin@gustaveroussy.fr., Durand A; Department of Medical Oncology, Edouard Herriot Hospital, Hospices Civils de Lyon, University of Lyon, Lyon, France., Beron A; Department of Nuclear Medicine, Huriez Hospital, University of Lille, Lille, France., Smith D; Department of Gastroenterology, Haut-Lévèque Hospital, University of Bordeaux, Bordeaux, France., Déandreis D; Department of Imaging, Nuclear Medicine Unit, Gustave Roussy, University Paris Saclay, Villejuif, France., Taieb D; Department of Nuclear Medicine, La Timone Hospital, Aix-Marseille University, Marseille, France., Ansquer C; Department of Nuclear Medicine, Hôtel Dieu Hospital Center, University of Nantes, Nantes, France., Dierickx L; Department of Nuclear Medicine, Oncopole Claudius Regaud, IUCT-Oncopole, University of Toulouse, Toulouse, France., Deshayes E; Department of Nuclear Medicine, Montpellier Cancer Institute, University of Montpellier, Montpellier, France., Hentic O; Department of Pancreatology and Digestive Oncology, Beaujon Hospital, University of Paris-Cité, Clichy, France., Moalla S; Department of Imaging, Gustave Roussy, University Paris Saclay, Villejuif, France., Menu Y; Department of Imaging, Gustave Roussy, University Paris Saclay, Villejuif, France., Lebtahi R; Department of Nuclear Medicine, Beaujon Hospital, University of Paris-Cité, Clichy, France., Assenat E; Department of Medical Oncology, CHU Montpellier, Montpellier, France., Touchefeu Y; Department of Digestive Disease, Hôtel Dieu Hospital Center, University of Nantes, Nantes, France., Guimbaud R; Department of Digestive Medical Oncology, Toulouse Hospital, CHU de Toulouse, Toulouse, France., Dahan L; Department of Digestive Oncology, La Timone Hospital, University of Marseille, Marseille, France., Lamartina L; Department of Imaging, Endocrine Oncology Unit, Gustave Roussy, University Paris Saclay, Villejuif, France., Cheurfa N; Office of Biostatistics and Epidemiology, Gustave Roussy, University Paris Saclay, Villejuif, France., Quak E; Department of Nuclear Medicine, François Baclesse Center, Caen, France., Bouhier-Leporrier K; Department of Gastroenterology, Caen Hospital, CHU Caen, Caen, France., Haissaguerre M; Department of Endocrinology, Bordeaux Hospital, University of Bordeaux, Bordeaux, France., Hindie E; Department of Nuclear Medicine, Bordeaux Hospital, University of Bordeaux, Bordeaux, France., Cao CD; Department of Endocrinology, Huriez Hospital, CHU Lille, Lille, France., Lombard-Bohas C; Department of Medical Oncology, Edouard Herriot Hospital, Hospices Civils de Lyon, University of Lyon, Lyon, France., Jannin A; Department of Endocrinology, Huriez Hospital, CHU Lille, Lille, France., Walter T; Department of Medical Oncology, Edouard Herriot Hospital, Hospices Civils de Lyon, University of Lyon, Lyon, France., Ducreux M; Department of Medical Oncology, Gustave Roussy, University Paris Saclay, Villejuif, France., Chaib S; Department of Pharmacy, Radiopharmacy, L Pradel Hospital, Hospices Civils de Lyon, University of Lyon, Lyon, France; Lyon Cancer Research Center, CNRS, INSERM, Lyon, France., Hadoux J; Department of Imaging, Endocrine Oncology Unit, Gustave Roussy, University Paris Saclay, Villejuif, France., Foulon S; Office of Biostatistics and Epidemiology, Gustave Roussy, University Paris Saclay, Villejuif, France; Inserm, University Paris-Saclay, CESP U1018, Oncostat, labeled Ligue Contre le Cancer, Villejuif, France.
Source: The Lancet. Oncology [Lancet Oncol] 2026 Jun; Vol. 27 (6), pp. 699-710.
Publication Type: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial; Multicenter Study; Comparative Study
Journal Info: Publisher: Lancet Pub. Group Country of Publication: England NLM ID: 100957246 Publication Model: Print Cited Medium: Internet ISSN: 1474-5488 (Electronic) Linking ISSN: 14702045 NLM ISO Abbreviation: Lancet Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: [<superscript>177</superscript>Lu]Lu-dota-tate versus sunitinib in patients with metastatic progressive neuroendocrine tumours of the pancreas (OCLURANDOM): a randomised, controlled, phase 2 trial.
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  Data: <searchLink fieldCode="AU" term="%22Baudin+E%22">Baudin E</searchLink>; Department of Imaging, Endocrine Oncology Unit, Gustave Roussy, University Paris Saclay, Villejuif, France. Electronic address: eric.baudin@gustaveroussy.fr.<br /><searchLink fieldCode="AU" term="%22Durand+A%22">Durand A</searchLink>; Department of Medical Oncology, Edouard Herriot Hospital, Hospices Civils de Lyon, University of Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Beron+A%22">Beron A</searchLink>; Department of Nuclear Medicine, Huriez Hospital, University of Lille, Lille, France.<br /><searchLink fieldCode="AU" term="%22Smith+D%22">Smith D</searchLink>; Department of Gastroenterology, Haut-Lévèque Hospital, University of Bordeaux, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Déandreis+D%22">Déandreis D</searchLink>; Department of Imaging, Nuclear Medicine Unit, Gustave Roussy, University Paris Saclay, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Taieb+D%22">Taieb D</searchLink>; Department of Nuclear Medicine, La Timone Hospital, Aix-Marseille University, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Ansquer+C%22">Ansquer C</searchLink>; Department of Nuclear Medicine, Hôtel Dieu Hospital Center, University of Nantes, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Dierickx+L%22">Dierickx L</searchLink>; Department of Nuclear Medicine, Oncopole Claudius Regaud, IUCT-Oncopole, University of Toulouse, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Deshayes+E%22">Deshayes E</searchLink>; Department of Nuclear Medicine, Montpellier Cancer Institute, University of Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Hentic+O%22">Hentic O</searchLink>; Department of Pancreatology and Digestive Oncology, Beaujon Hospital, University of Paris-Cité, Clichy, France.<br /><searchLink fieldCode="AU" term="%22Moalla+S%22">Moalla S</searchLink>; Department of Imaging, Gustave Roussy, University Paris Saclay, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Menu+Y%22">Menu Y</searchLink>; Department of Imaging, Gustave Roussy, University Paris Saclay, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Lebtahi+R%22">Lebtahi R</searchLink>; Department of Nuclear Medicine, Beaujon Hospital, University of Paris-Cité, Clichy, France.<br /><searchLink fieldCode="AU" term="%22Assenat+E%22">Assenat E</searchLink>; Department of Medical Oncology, CHU Montpellier, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Touchefeu+Y%22">Touchefeu Y</searchLink>; Department of Digestive Disease, Hôtel Dieu Hospital Center, University of Nantes, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Guimbaud+R%22">Guimbaud R</searchLink>; Department of Digestive Medical Oncology, Toulouse Hospital, CHU de Toulouse, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Dahan+L%22">Dahan L</searchLink>; Department of Digestive Oncology, La Timone Hospital, University of Marseille, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Lamartina+L%22">Lamartina L</searchLink>; Department of Imaging, Endocrine Oncology Unit, Gustave Roussy, University Paris Saclay, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Cheurfa+N%22">Cheurfa N</searchLink>; Office of Biostatistics and Epidemiology, Gustave Roussy, University Paris Saclay, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Quak+E%22">Quak E</searchLink>; Department of Nuclear Medicine, François Baclesse Center, Caen, France.<br /><searchLink fieldCode="AU" term="%22Bouhier-Leporrier+K%22">Bouhier-Leporrier K</searchLink>; Department of Gastroenterology, Caen Hospital, CHU Caen, Caen, France.<br /><searchLink fieldCode="AU" term="%22Haissaguerre+M%22">Haissaguerre M</searchLink>; Department of Endocrinology, Bordeaux Hospital, University of Bordeaux, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Hindie+E%22">Hindie E</searchLink>; Department of Nuclear Medicine, Bordeaux Hospital, University of Bordeaux, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Cao+CD%22">Cao CD</searchLink>; Department of Endocrinology, Huriez Hospital, CHU Lille, Lille, France.<br /><searchLink fieldCode="AU" term="%22Lombard-Bohas+C%22">Lombard-Bohas C</searchLink>; Department of Medical Oncology, Edouard Herriot Hospital, Hospices Civils de Lyon, University of Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Jannin+A%22">Jannin A</searchLink>; Department of Endocrinology, Huriez Hospital, CHU Lille, Lille, France.<br /><searchLink fieldCode="AU" term="%22Walter+T%22">Walter T</searchLink>; Department of Medical Oncology, Edouard Herriot Hospital, Hospices Civils de Lyon, University of Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Ducreux+M%22">Ducreux M</searchLink>; Department of Medical Oncology, Gustave Roussy, University Paris Saclay, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Chaib+S%22">Chaib S</searchLink>; Department of Pharmacy, Radiopharmacy, L Pradel Hospital, Hospices Civils de Lyon, University of Lyon, Lyon, France; Lyon Cancer Research Center, CNRS, INSERM, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Hadoux+J%22">Hadoux J</searchLink>; Department of Imaging, Endocrine Oncology Unit, Gustave Roussy, University Paris Saclay, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Foulon+S%22">Foulon S</searchLink>; Office of Biostatistics and Epidemiology, Gustave Roussy, University Paris Saclay, Villejuif, France; Inserm, University Paris-Saclay, CESP U1018, Oncostat, labeled Ligue Contre le Cancer, Villejuif, France.
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