A Slc5a6-deficient mouse model reveals metabolically driven cardiomyopathy with therapeutic potential for vitamin-based intervention.
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| Title: | A Slc5a6-deficient mouse model reveals metabolically driven cardiomyopathy with therapeutic potential for vitamin-based intervention. |
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| Authors: | Fullerton MO; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Phillips LC; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.; Department of Pharmacology, University of Oxford, United Kingdom., Redgrave RE; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Spray L; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Haufroid V; Louvain Center for Toxicology and Applied Pharmacology (LTAP), Institut de Recherche Expérimentale et Clinique (IREC), UCLouvain, Brussels, Belgium., Merces G; Image Analysis Unit, Newcastle University, Newcastle upon Tyne, United Kingdom., Kerridge ST; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Richardson GD; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Mercier N; Department of Pediatrics, CHU HELORA Jo, La Louvière, Belgium., Roland D; Department of Human Genetics, Center for Inherited Metabolic Disorders, Institute of Pathology and Genetics, Gosselies, Belgium., Crossley R; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Morgan AD; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Dewulf JP; Louvain Center for Toxicology and Applied Pharmacology (LTAP), Institut de Recherche Expérimentale et Clinique (IREC), UCLouvain, Brussels, Belgium.; Metabolic Research Group, de Duve Institute, UCLouvain, Brussels, Belgium.; Biochemical Genetics and Newborn Screening Laboratory, Department of laboratory medicine & Institut des Maladies Rares, Cliniques Universitaires Saint-Luc, UCLouvain, Brussels, Belgium., Burn J; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Bamforth SD; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Phillips HM; Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom. |
| Source: | JCI insight [JCI Insight] 2026 Jun 02; Vol. 11 (14). Date of Electronic Publication: 2026 Jun 02 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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