Prognostic value of cervical length for spontaneous preterm birth in asymptomatic women with singleton pregnancy: An individual participant data meta-analysis.

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Title: Prognostic value of cervical length for spontaneous preterm birth in asymptomatic women with singleton pregnancy: An individual participant data meta-analysis.
Authors: Hughes K; Department of Obstetrics and Gynaecology, Monash University, Melbourne, Australia., Nguyen D; NHMRC Clinical Trials Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia., Aberoumand M; NHMRC Clinical Trials Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia., Ford H; Pauline Gandel Imaging Centre, Royal Women's Hospital, Melbourne, Australia., Clarke E; Department of Obstetrics and Gynaecology, Monash University, Melbourne, Australia., Banos Lopez N; Department of Maternal-Fetal Medicine, BCNatal, Barcelona Centre for Maternal-Fetal and Neonatal Medicine, Hospital Clínic and Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain., Dziadosz M; RWJ Barnabas Health, Jersey City, New Jersey, United States of America.; New Jersey Perinatal Associates, Livingston, New Jersey, United States of America., Fischer R; Department of Obstetrics and Gynecology, Cooper Medical School of Rowan University, Cooper University Hospital, Camden, New Jersey, United States of America., Souza RT; Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Campinas, Sao Paulo, Brazil., Cecatti JG; Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Campinas, Sao Paulo, Brazil., Orzechowski K; Obstetrics and Gynecology Academic Department, School of Medicine, Georgetown University, Washington, District of Columbia, United States of America., Olson-Chen C; Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York, United States of America., Peixoto AB; Department of Obstetrics and Gynecology, University of Uberaba, Minas Gerais, Brazil., Phupong V; Department of Obstetrics and Gynecology, Chulalongkorn University, Bangkok, Thailand., Rosenbloom J; Department of Obstetrics and Gynecology, The Hebrew University of Jerusalem, Jerusalem, Israel., Son M; Department of Obstetrics and Gynecology, Weill Cornell Medical College, New York, New York, United States of America., Souka A; Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens School of Medicine, Athens, Greece., Du L; Department of Medical Ultrasonics at The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China., Esplin MS; Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, Utah, United States of America., Granese R; Department of Biomedical, Dental, Morphological and Functional Imaging Science, University of Messina, Messina, Italy., Gupta S; Carnegie Imaging for Women, Mount Sinai West, New York, New York, United States of America., Kazemier B; Department of Obstetrics and Gynecology, Amsterdam UMC, Amsterdam, The Netherlands.; Amsterdam Reproduction and Development Research Institute, Amsterdam, The Netherlands., Kindinger L; Obstetrics and Gynaecology, University of Western Australia Medical School, Perth, Western Australia, Australia., Kuusela P; Research Department of Obstetrics and Gynecology, University of Gothenburg, Göteborg, Sweden., Van der Ven J; Department of Obstetrics and Gynecology, Meir Medical Center, Kfar Saba, Israel., Weitzner O; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, United States of America., Minis E; Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Massachusetts General Hospital, Boston, Massachusetts, United States of America.; Department of Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School, Boston, Massachusetts, United States of America., Llobet AF; Maternal and Fetal Medicine, Vall d'Hebron Research Institute, Barcelona, Spain., Frey H; Department of Obstetrics and Gynecology, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America., Bagga R; Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Mishra S; Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India., Patberg E; Department of Obstetrics, Gynecology and Reproductive Services, University of California San Francisco, San Francisco, California, United States of America., Bennett P; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom., Hall M; Division of Women's Health, King's College London, Women's Health Academic Centre, St Thomas' Hospital, London, United Kingdom., Shennan A; Division of Women's Health, King's College London, Women's Health Academic Centre, St Thomas' Hospital, London, United Kingdom., Brennecke S; Pregnancy Research Centre, Royal Women's Hospital, Melbourne, Australia.; Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia., Thangaratinam S; Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom.; Liverpool Women's NHS Foundation Trust, Liverpool, United Kingdom.; NIHR North West Coast Applied Research Collaboration, University of Liverpool, Liverpool, United Kingdom., Seidler AL; Department of Child and Adolescent Psychiatry, University Medical Centre Rostock, Rostock, Germany.; German Center for Child and Adolescent Health (DZKJ), Partner Site Greifswald/Rostock, Rostock, Germany., Mol BW; Department of Obstetrics and Gynaecology, Monash University, Melbourne, Australia.; Department of Obstetrics and Gynaecology, University of Aberdeen, Aberdeen, Scotland, United Kingdom., Wang R; NHMRC Clinical Trials Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.
Source: PLoS medicine [PLoS Med] 2026 Jun 02; Vol. 23 (6), pp. e1004653. Date of Electronic Publication: 2026 Jun 02 (Print Publication: 2026).
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101231360 Publication Model: eCollection Cited Medium: Internet ISSN: 1549-1676 (Electronic) Linking ISSN: 15491277 NLM ISO Abbreviation: PLoS Med Subsets: MEDLINE
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  Data: Prognostic value of cervical length for spontaneous preterm birth in asymptomatic women with singleton pregnancy: An individual participant data meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Hughes+K%22">Hughes K</searchLink>; Department of Obstetrics and Gynaecology, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Nguyen+D%22">Nguyen D</searchLink>; NHMRC Clinical Trials Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Aberoumand+M%22">Aberoumand M</searchLink>; NHMRC Clinical Trials Centre, Faculty of Medicine and Health, University of Sydney, Sydney, Australia.<br /><searchLink fieldCode="AU" term="%22Ford+H%22">Ford H</searchLink>; Pauline Gandel Imaging Centre, Royal Women's Hospital, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Clarke+E%22">Clarke E</searchLink>; Department of Obstetrics and Gynaecology, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Banos+Lopez+N%22">Banos Lopez N</searchLink>; Department of Maternal-Fetal Medicine, BCNatal, Barcelona Centre for Maternal-Fetal and Neonatal Medicine, Hospital Clínic and Hospital Sant Joan de Déu, University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Dziadosz+M%22">Dziadosz M</searchLink>; RWJ Barnabas Health, Jersey City, New Jersey, United States of America.; New Jersey Perinatal Associates, Livingston, New Jersey, United States of America.<br /><searchLink fieldCode="AU" term="%22Fischer+R%22">Fischer R</searchLink>; Department of Obstetrics and Gynecology, Cooper Medical School of Rowan University, Cooper University Hospital, Camden, New Jersey, United States of America.<br /><searchLink fieldCode="AU" term="%22Souza+RT%22">Souza RT</searchLink>; Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Campinas, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Cecatti+JG%22">Cecatti JG</searchLink>; Department of Obstetrics and Gynecology, Faculty of Medical Sciences, University of Campinas, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Orzechowski+K%22">Orzechowski K</searchLink>; Obstetrics and Gynecology Academic Department, School of Medicine, Georgetown University, Washington, District of Columbia, United States of America.<br /><searchLink fieldCode="AU" term="%22Olson-Chen+C%22">Olson-Chen C</searchLink>; Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Peixoto+AB%22">Peixoto AB</searchLink>; Department of Obstetrics and Gynecology, University of Uberaba, Minas Gerais, Brazil.<br /><searchLink fieldCode="AU" term="%22Phupong+V%22">Phupong V</searchLink>; Department of Obstetrics and Gynecology, Chulalongkorn University, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Rosenbloom+J%22">Rosenbloom J</searchLink>; Department of Obstetrics and Gynecology, The Hebrew University of Jerusalem, Jerusalem, Israel.<br /><searchLink fieldCode="AU" term="%22Son+M%22">Son M</searchLink>; Department of Obstetrics and Gynecology, Weill Cornell Medical College, New York, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Souka+A%22">Souka A</searchLink>; Department of Obstetrics and Gynecology, National and Kapodistrian University of Athens School of Medicine, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Du+L%22">Du L</searchLink>; Department of Medical Ultrasonics at The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Esplin+MS%22">Esplin MS</searchLink>; Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, Utah, United States of America.<br /><searchLink fieldCode="AU" term="%22Granese+R%22">Granese R</searchLink>; Department of Biomedical, Dental, Morphological and Functional Imaging Science, University of Messina, Messina, Italy.<br /><searchLink fieldCode="AU" term="%22Gupta+S%22">Gupta S</searchLink>; Carnegie Imaging for Women, Mount Sinai West, New York, New York, United States of America.<br /><searchLink fieldCode="AU" term="%22Kazemier+B%22">Kazemier B</searchLink>; Department of Obstetrics and Gynecology, Amsterdam UMC, Amsterdam, The Netherlands.; Amsterdam Reproduction and Development Research Institute, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kindinger+L%22">Kindinger L</searchLink>; 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Department of Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School, Boston, Massachusetts, United States of America.<br /><searchLink fieldCode="AU" term="%22Llobet+AF%22">Llobet AF</searchLink>; Maternal and Fetal Medicine, Vall d'Hebron Research Institute, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Frey+H%22">Frey H</searchLink>; Department of Obstetrics and Gynecology, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States of America.<br /><searchLink fieldCode="AU" term="%22Bagga+R%22">Bagga R</searchLink>; Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.<br /><searchLink fieldCode="AU" term="%22Mishra+S%22">Mishra S</searchLink>; Department of Obstetrics and Gynaecology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.<br /><searchLink fieldCode="AU" term="%22Patberg+E%22">Patberg E</searchLink>; Department of Obstetrics, Gynecology and Reproductive Services, University of California San Francisco, San Francisco, California, United States of America.<br /><searchLink fieldCode="AU" term="%22Bennett+P%22">Bennett P</searchLink>; Department of Metabolism, Digestion and Reproduction, Imperial College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hall+M%22">Hall M</searchLink>; Division of Women's Health, King's College London, Women's Health Academic Centre, St Thomas' Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Shennan+A%22">Shennan A</searchLink>; Division of Women's Health, King's College London, Women's Health Academic Centre, St Thomas' Hospital, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Brennecke+S%22">Brennecke S</searchLink>; Pregnancy Research Centre, Royal Women's Hospital, Melbourne, Australia.; Department of Obstetrics, Gynaecology and Newborn Health, The University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Thangaratinam+S%22">Thangaratinam S</searchLink>; Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, United Kingdom.; Liverpool Women's NHS Foundation Trust, Liverpool, United Kingdom.; 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