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Hedyotis diffusa injection suppresses breast cancer progression and lung metastasis through dual targeting of PTK2B and CCN2.

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Title: Hedyotis diffusa injection suppresses breast cancer progression and lung metastasis through dual targeting of PTK2B and CCN2.
Authors: Ren A; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China., Yang L; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China., Liao Q; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China., Ni S; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China., Li X; School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China., Chen S; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China., Wang X; School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China., Wang Y; School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China., Li J; School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China., Sun R; School of Nursing, Yunnan University of Chinese Medicine, Kunming 650500, China. Electronic address: sunruifen@ynucm.edu.cn., Su X; Scientific Research and Experimental Center, Yunnan University of Chinese Medicine, Kunming 650500, China. Electronic address: suxs163@163.com.
Source: Phytomedicine : international journal of phytotherapy and phytopharmacology [Phytomedicine] 2026 Jul 25; Vol. 157, pp. 158352. Date of Electronic Publication: 2026 May 26.
Publication Type: Journal Article
Journal Info: Publisher: Urban & Fischer Verlag Country of Publication: Germany NLM ID: 9438794 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-095X (Electronic) Linking ISSN: 09447113 NLM ISO Abbreviation: Phytomedicine Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Hedyotis diffusa injection suppresses breast cancer progression and lung metastasis through dual targeting of PTK2B and CCN2.
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  Data: <searchLink fieldCode="AU" term="%22Ren+A%22">Ren A</searchLink>; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.<br /><searchLink fieldCode="AU" term="%22Liao+Q%22">Liao Q</searchLink>; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.<br /><searchLink fieldCode="AU" term="%22Ni+S%22">Ni S</searchLink>; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; School of Basic Medical Sciences, Yunnan University of Chinese Medicine, Kunming 650500, China.<br /><searchLink fieldCode="AU" term="%22Sun+R%22">Sun R</searchLink>; School of Nursing, Yunnan University of Chinese Medicine, Kunming 650500, China. Electronic address: sunruifen@ynucm.edu.cn.<br /><searchLink fieldCode="AU" term="%22Su+X%22">Su X</searchLink>; Scientific Research and Experimental Center, Yunnan University of Chinese Medicine, Kunming 650500, China. Electronic address: suxs163@163.com.
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  Data: <searchLink fieldCode="JN" term="%229438794%22">Phytomedicine : international journal of phytotherapy and phytopharmacology</searchLink> [Phytomedicine] 2026 Jul 25; Vol. 157, pp. 158352. <i>Date of Electronic Publication: </i>2026 May 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Urban+%26+Fischer+Verlag%22">Urban & Fischer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9438794 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1618-095X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209447113%22">09447113 </searchLink><i>NLM ISO Abbreviation: </i>Phytomedicine <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.phymed.2026.158352
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      – TitleFull: Hedyotis diffusa injection suppresses breast cancer progression and lung metastasis through dual targeting of PTK2B and CCN2.
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              Text: 2026 Jul 25
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