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Serum neurofilaments for motoneuron and dementia diseases: a German multicenter cohort study.

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Title: Serum neurofilaments for motoneuron and dementia diseases: a German multicenter cohort study.
Authors: Barba L; Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany., Steinacker P; Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany., Halbgebauer S; Department of Neurology, Ulm University Hospital, Ulm, Germany., Oeckl P; Department of Neurology, Ulm University Hospital, Ulm, Germany.; German Center for Neurodegenerative Diseases (DZNE) Ulm, Ulm, Germany., Landwehrmeyer B; Department of Neurology, Ulm University Hospital, Ulm, Germany., Weishaupt J; Department of Neurology, Ulm University Hospital, Ulm, Germany., Verde F; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy., Ticozzi N; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Pathophysiology and Transplantation, Dino Ferrari' Center, Università Degli Studi Di Milano, Milan, Italy., Silani V; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Pathophysiology and Transplantation, Dino Ferrari' Center, Università Degli Studi Di Milano, Milan, Italy., Levin J; Department of Neurology, LMU University Hospital, LMU Munich, Munich, Germany., Schönecker S; Department of Neurology, LMU University Hospital, LMU Munich, Munich, Germany., Kornhuber J; Department of Psychiatry, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany., Prudlo J; Department of Neurology, University of Rostock, and German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany., Schroeter ML; Clinic for Cognitive Neurology, University Clinic Leipzig, and Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany., Fassbender K; Department of Neurology, Saarland University, Homburg, Germany., Fliessbach K; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn and DZNE Bonn, Bonn, Germany., Diehl-Schmid J; Department of Psychiatry and Psychotherapy, Technical University of Munich, School of Medicine and Health, TUM University Hospital, Munich, Germany.; Clinical Center for Psychiatry, Psychotherapy, Psychosomatic Medicine, Geriatrics and Neurology, Kbo-Inn-Salzach-Klinikum, Wasserburg/Inn, Germany., Jahn H; Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Lauer M; Department of Psychiatry and Psychotherapy, University Hospital Würzburg, Würzburg, Germany., Dorst J; Department of Neurology, Ulm University Hospital, Ulm, Germany., Rosenbohm A; Department of Neurology, Ulm University Hospital, Ulm, Germany., Abu-Rumeileh S; Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany., Anderl-Straub S; Department of Neurology, Ulm University Hospital, Ulm, Germany., Söntgerth M; Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany., Böhm F; Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany., Wiltfang J; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, and DZNE, Goettingen, Germany., Otto M; Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany. markus.otto@uk-halle.de.
Source: Journal of neurology [J Neurol] 2026 Jun 02; Vol. 273 (6). Date of Electronic Publication: 2026 Jun 02.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Serum neurofilaments for motoneuron and dementia diseases: a German multicenter cohort study.
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  Data: <searchLink fieldCode="AU" term="%22Barba+L%22">Barba L</searchLink>; Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany.<br /><searchLink fieldCode="AU" term="%22Steinacker+P%22">Steinacker P</searchLink>; Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany.<br /><searchLink fieldCode="AU" term="%22Halbgebauer+S%22">Halbgebauer S</searchLink>; Department of Neurology, Ulm University Hospital, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Oeckl+P%22">Oeckl P</searchLink>; Department of Neurology, Ulm University Hospital, Ulm, Germany.; German Center for Neurodegenerative Diseases (DZNE) Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Landwehrmeyer+B%22">Landwehrmeyer B</searchLink>; Department of Neurology, Ulm University Hospital, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Weishaupt+J%22">Weishaupt J</searchLink>; Department of Neurology, Ulm University Hospital, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Verde+F%22">Verde F</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ticozzi+N%22">Ticozzi N</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Pathophysiology and Transplantation, Dino Ferrari' Center, Università Degli Studi Di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Silani+V%22">Silani V</searchLink>; Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Pathophysiology and Transplantation, Dino Ferrari' Center, Università Degli Studi Di Milano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Levin+J%22">Levin J</searchLink>; Department of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schönecker+S%22">Schönecker S</searchLink>; Department of Neurology, LMU University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kornhuber+J%22">Kornhuber J</searchLink>; Department of Psychiatry, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Prudlo+J%22">Prudlo J</searchLink>; Department of Neurology, University of Rostock, and German Center for Neurodegenerative Diseases (DZNE), Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Schroeter+ML%22">Schroeter ML</searchLink>; Clinic for Cognitive Neurology, University Clinic Leipzig, and Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Fassbender+K%22">Fassbender K</searchLink>; Department of Neurology, Saarland University, Homburg, Germany.<br /><searchLink fieldCode="AU" term="%22Fliessbach+K%22">Fliessbach K</searchLink>; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn and DZNE Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Diehl-Schmid+J%22">Diehl-Schmid J</searchLink>; Department of Psychiatry and Psychotherapy, Technical University of Munich, School of Medicine and Health, TUM University Hospital, Munich, Germany.; Clinical Center for Psychiatry, Psychotherapy, Psychosomatic Medicine, Geriatrics and Neurology, Kbo-Inn-Salzach-Klinikum, Wasserburg/Inn, Germany.<br /><searchLink fieldCode="AU" term="%22Jahn+H%22">Jahn H</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lauer+M%22">Lauer M</searchLink>; Department of Psychiatry and Psychotherapy, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Dorst+J%22">Dorst J</searchLink>; Department of Neurology, Ulm University Hospital, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Rosenbohm+A%22">Rosenbohm A</searchLink>; Department of Neurology, Ulm University Hospital, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Abu-Rumeileh+S%22">Abu-Rumeileh S</searchLink>; Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany.<br /><searchLink fieldCode="AU" term="%22Anderl-Straub+S%22">Anderl-Straub S</searchLink>; Department of Neurology, Ulm University Hospital, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Söntgerth+M%22">Söntgerth M</searchLink>; Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany.<br /><searchLink fieldCode="AU" term="%22Böhm+F%22">Böhm F</searchLink>; Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany.<br /><searchLink fieldCode="AU" term="%22Wiltfang+J%22">Wiltfang J</searchLink>; Department of Psychiatry and Psychotherapy, University Medical Center Goettingen, and DZNE, Goettingen, Germany.<br /><searchLink fieldCode="AU" term="%22Otto+M%22">Otto M</searchLink>; Department of Neurology, Martin-Luther-University of Halle-Wittenberg, Ernst-Grube-Strasse 40, 06120, Halle (Saale), Germany. markus.otto@uk-halle.de.
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