Progression-free survival as a potential surrogate endpoint for overall survival after conversion therapy for unresectable hepatocellular carcinoma (GUIDANCE008).
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| Title: | Progression-free survival as a potential surrogate endpoint for overall survival after conversion therapy for unresectable hepatocellular carcinoma (GUIDANCE008). |
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| Authors: | Wu JW; Infectious Disease Laboratory, Guangxi AlDs Clinical Treatment Center (Nanning), The Fourth People's Hospital of Nanning, Chang Gang Rd ErLi 1, Nanning, 530023, China., Yang DL; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, He Di Rd 71, Nanning, 530021, China., Chen SC; Department of Hepatobiliary Surgery, Wuzhou People's Hospital, Wuzhou, 543001, China., Li MJ; Department of Hepatobiliary Pancreatic Surgery, Guilin People's Hospital, Guilin, 542001, China., Liang YR; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Qinzhou, Qinzhou, 535000, China., Wang XY; Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Guilin Medical University, Guilin, 541199, China., Yao HB; Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Guilin Medical University, Guilin, 541199, China., Liu J; Department of Hepatobiliary Pancreatic Surgery, Guilin People's Hospital, Guilin, 542001, China., Wu PS; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Qinzhou, Qinzhou, 535000, China., Peng N; Department of Hepatobiliary Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China., Nong JL; Department of Hepatobiliary Surgery, Hengzhou City People's Hospital, Hengzhou, 530300, China., Yu YQ; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541002, China., Ye L; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541002, China., Su Z; Department of Hepatobiliary Pancreatic Surgery, First People's Hospital of Nanning, Nanning, 530016, China., Qin C; Department of Hepatobiliary Surgery, Liuzhou People's Hospital, Liuzhou, 545006, China., Chen K; Department of General Surgery, Second Affiliated Hospital of Guangxi Medical University, Nanning, 530007, China., Yan YH; Department of General Surgery, Second Affiliated Hospital of Guangxi Medical University, Nanning, 530007, China., Zeng FJ; Department of Hepatobiliary Surgery, Wuzhou Red Cross Hospital, Wuzhou, 543002, China., Liu SP; Department of Hepatobiliary and Pancreatic Surgery, Eighth Affiliated Hospital of the Guangxi Medical University, Guigang, 537100, China., Wu MS; Department of Oncology, People's Hospital of Beiliu, Beiliu, 537400, China., Yang FQ; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Yulin, Yulin, 537800, China., Lai YC; Department of Hepatobiliary Gland Surgery, Beihai People's Hospital, Beihai, 536000, China., Dong XF; Department of Hepatobiliary, Pancreatic and Spleen Surgery, People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, 530021, China., Zhong TM; Hepatobiliary Surgery Department, Baise People's Hospital, Baise, 533000, China., Pang QQ; Department of Oncology, Liuzhou Workers Hospital, Liuzhou, 545005, China., Li FX; Department of Hepatobiliary, Pancreatic and Spleen Surgery, People's Hospital of Hezhou, Hezhou, 532800, China., Liu AQ; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, He Di Rd 71, Nanning, 530021, China., Ma L; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, He Di Rd 71, Nanning, 530021, China., Zhong JH; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, He Di Rd 71, Nanning, 530021, China. zhongjianhong@gxmu.edu.cn., Cen P; Infectious Disease Laboratory, Guangxi AlDs Clinical Treatment Center (Nanning), The Fourth People's Hospital of Nanning, Chang Gang Rd ErLi 1, Nanning, 530023, China. cenping877@163.com. |
| Corporate Authors: | GUIDANCE investigators |
| Source: | Scientific reports [Sci Rep] 2026 Jun 03. Date of Electronic Publication: 2026 Jun 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42230684 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Progression-free survival as a potential surrogate endpoint for overall survival after conversion therapy for unresectable hepatocellular carcinoma (GUIDANCE008). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Wu+JW%22">Wu JW</searchLink>; Infectious Disease Laboratory, Guangxi AlDs Clinical Treatment Center (Nanning), The Fourth People's Hospital of Nanning, Chang Gang Rd ErLi 1, Nanning, 530023, China.<br /><searchLink fieldCode="AU" term="%22Yang+DL%22">Yang DL</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, He Di Rd 71, Nanning, 530021, China.<br /><searchLink fieldCode="AU" term="%22Chen+SC%22">Chen SC</searchLink>; Department of Hepatobiliary Surgery, Wuzhou People's Hospital, Wuzhou, 543001, China.<br /><searchLink fieldCode="AU" term="%22Li+MJ%22">Li MJ</searchLink>; Department of Hepatobiliary Pancreatic Surgery, Guilin People's Hospital, Guilin, 542001, China.<br /><searchLink fieldCode="AU" term="%22Liang+YR%22">Liang YR</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Qinzhou, Qinzhou, 535000, China.<br /><searchLink fieldCode="AU" term="%22Wang+XY%22">Wang XY</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Guilin Medical University, Guilin, 541199, China.<br /><searchLink fieldCode="AU" term="%22Yao+HB%22">Yao HB</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Second Affiliated Hospital of Guilin Medical University, Guilin, 541199, China.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Department of Hepatobiliary Pancreatic Surgery, Guilin People's Hospital, Guilin, 542001, China.<br /><searchLink fieldCode="AU" term="%22Wu+PS%22">Wu PS</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Qinzhou, Qinzhou, 535000, China.<br /><searchLink fieldCode="AU" term="%22Peng+N%22">Peng N</searchLink>; Department of Hepatobiliary Surgery, First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.<br /><searchLink fieldCode="AU" term="%22Nong+JL%22">Nong JL</searchLink>; Department of Hepatobiliary Surgery, Hengzhou City People's Hospital, Hengzhou, 530300, China.<br /><searchLink fieldCode="AU" term="%22Yu+YQ%22">Yu YQ</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541002, China.<br /><searchLink fieldCode="AU" term="%22Ye+L%22">Ye L</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guilin Medical University, Guilin, 541002, China.<br /><searchLink fieldCode="AU" term="%22Su+Z%22">Su Z</searchLink>; Department of Hepatobiliary Pancreatic Surgery, First People's Hospital of Nanning, Nanning, 530016, China.<br /><searchLink fieldCode="AU" term="%22Qin+C%22">Qin C</searchLink>; Department of Hepatobiliary Surgery, Liuzhou People's Hospital, Liuzhou, 545006, China.<br /><searchLink fieldCode="AU" term="%22Chen+K%22">Chen K</searchLink>; Department of General Surgery, Second Affiliated Hospital of Guangxi Medical University, Nanning, 530007, China.<br /><searchLink fieldCode="AU" term="%22Yan+YH%22">Yan YH</searchLink>; Department of General Surgery, Second Affiliated Hospital of Guangxi Medical University, Nanning, 530007, China.<br /><searchLink fieldCode="AU" term="%22Zeng+FJ%22">Zeng FJ</searchLink>; Department of Hepatobiliary Surgery, Wuzhou Red Cross Hospital, Wuzhou, 543002, China.<br /><searchLink fieldCode="AU" term="%22Liu+SP%22">Liu SP</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Eighth Affiliated Hospital of the Guangxi Medical University, Guigang, 537100, China.<br /><searchLink fieldCode="AU" term="%22Wu+MS%22">Wu MS</searchLink>; Department of Oncology, People's Hospital of Beiliu, Beiliu, 537400, China.<br /><searchLink fieldCode="AU" term="%22Yang+FQ%22">Yang FQ</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, First People's Hospital of Yulin, Yulin, 537800, China.<br /><searchLink fieldCode="AU" term="%22Lai+YC%22">Lai YC</searchLink>; Department of Hepatobiliary Gland Surgery, Beihai People's Hospital, Beihai, 536000, China.<br /><searchLink fieldCode="AU" term="%22Dong+XF%22">Dong XF</searchLink>; Department of Hepatobiliary, Pancreatic and Spleen Surgery, People's Hospital of Guangxi Zhuang Autonomous Region, Guangxi Academy of Medical Sciences, Nanning, 530021, China.<br /><searchLink fieldCode="AU" term="%22Zhong+TM%22">Zhong TM</searchLink>; Hepatobiliary Surgery Department, Baise People's Hospital, Baise, 533000, China.<br /><searchLink fieldCode="AU" term="%22Pang+QQ%22">Pang QQ</searchLink>; Department of Oncology, Liuzhou Workers Hospital, Liuzhou, 545005, China.<br /><searchLink fieldCode="AU" term="%22Li+FX%22">Li FX</searchLink>; Department of Hepatobiliary, Pancreatic and Spleen Surgery, People's Hospital of Hezhou, Hezhou, 532800, China.<br /><searchLink fieldCode="AU" term="%22Liu+AQ%22">Liu AQ</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, He Di Rd 71, Nanning, 530021, China.<br /><searchLink fieldCode="AU" term="%22Ma+L%22">Ma L</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, He Di Rd 71, Nanning, 530021, China.<br /><searchLink fieldCode="AU" term="%22Zhong+JH%22">Zhong JH</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, He Di Rd 71, Nanning, 530021, China. zhongjianhong@gxmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Cen+P%22">Cen P</searchLink>; Infectious Disease Laboratory, Guangxi AlDs Clinical Treatment Center (Nanning), The Fourth People's Hospital of Nanning, Chang Gang Rd ErLi 1, Nanning, 530023, China. cenping877@163.com. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22GUIDANCE+investigators%22">GUIDANCE investigators</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Jun 03. <i>Date of Electronic Publication: </i>2026 Jun 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41598-026-53344-3 Languages: – Code: eng Text: English Titles: – TitleFull: Progression-free survival as a potential surrogate endpoint for overall survival after conversion therapy for unresectable hepatocellular carcinoma (GUIDANCE008). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Wu JW – PersonEntity: Name: NameFull: Yang DL – PersonEntity: Name: NameFull: Chen SC – PersonEntity: Name: NameFull: Li MJ – PersonEntity: Name: NameFull: Liang YR – PersonEntity: Name: NameFull: Wang XY – PersonEntity: Name: NameFull: Yao HB – PersonEntity: Name: NameFull: Liu J – PersonEntity: Name: NameFull: Wu PS – PersonEntity: Name: NameFull: Peng N – PersonEntity: Name: NameFull: Nong JL – PersonEntity: Name: NameFull: Yu YQ – PersonEntity: Name: NameFull: Ye L – PersonEntity: Name: NameFull: Su Z – PersonEntity: Name: NameFull: Qin C – PersonEntity: Name: NameFull: Chen K – PersonEntity: Name: NameFull: Yan YH – PersonEntity: Name: NameFull: Zeng FJ – PersonEntity: Name: NameFull: Liu SP – PersonEntity: Name: NameFull: Wu MS – PersonEntity: Name: NameFull: Yang FQ – PersonEntity: Name: NameFull: Lai YC – PersonEntity: Name: NameFull: Dong XF – PersonEntity: Name: NameFull: Zhong TM – PersonEntity: Name: NameFull: Pang QQ – PersonEntity: Name: NameFull: Li FX – PersonEntity: Name: NameFull: Liu AQ – PersonEntity: Name: NameFull: Ma L – PersonEntity: Name: NameFull: Zhong JH – PersonEntity: Name: NameFull: Cen P IsPartOfRelationships: – BibEntity: Dates: – D: 03 M: 06 Text: 2026 Jun 03 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2045-2322 Titles: – TitleFull: Scientific reports Type: main |
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