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Genetics of major depressive disorder in a homogeneous population with uniform phenotyping.

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Title: Genetics of major depressive disorder in a homogeneous population with uniform phenotyping.
Authors: Huider F; Department of Complex Trait Genetics, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands. f.huider@vu.nl.; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands. f.huider@vu.nl.; Department of Biological Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands. f.huider@vu.nl., Milaneschi Y; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Psychiatry, Amsterdam UMC location Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Complex Trait Genetics, 1081, Amsterdam, The Netherlands., Pool R; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Biological Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands., Maciel BAPC; Department of Complex Trait Genetics, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands., Gordon SD; Brain and Mental Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Han J; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Rietman ML; Center for Prevention, Lifestyle and Health, Dutch National Institute for Public Health and the Environment, 3721, Bilthoven, The Netherlands., Kok AAL; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Psychiatry, Amsterdam UMC location Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.; Department of Epidemiology and Data Science, Amsterdam UMC, 1081, Amsterdam, The Netherlands., Galesloot TE; IQ Health Science Department, Radboud University Medical Center, 6525, Nijmegen, The Netherlands., Mitchell BL; Brain and Mental Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Australia., 't Hart LM; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Epidemiology and Data Science, Amsterdam UMC, 1081, Amsterdam, The Netherlands.; Department of Cell and Chemical Biology, Leiden University Medical Center, 2333, Leiden, The Netherlands.; Department of Biomedical Data Sciences, Section Molecular Epidemiology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands., Rutters F; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Epidemiology and Data Science, Amsterdam UMC, 1081, Amsterdam, The Netherlands., Blom MT; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of General Practice, Amsterdam UMC, 1081, Amsterdam, The Netherlands., Rhebergen D; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Psychiatry, Amsterdam UMC location Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Complex Trait Genetics, 1081, Amsterdam, The Netherlands., Visser M; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands., Brouwer IA; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands., Feskens E; Division of Human Nutrition and Health, Wageningen University & Research, 6700, Wageningen, The Netherlands., Hartman CA; Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9713, Groningen, The Netherlands., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9713, Groningen, The Netherlands., Bot M; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Psychiatry, Amsterdam UMC location Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Complex Trait Genetics, 1081, Amsterdam, The Netherlands., de Geus EJC; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Biological Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands., Kiemeney LA; IQ Health Science Department, Radboud University Medical Center, 6525, Nijmegen, The Netherlands.; Department of Urology and Department for Health Evidence, Radboud University Medical Center, 6525, Nijmegen, The Netherlands., Huisman M; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Epidemiology and Data Science, Amsterdam UMC, 1081, Amsterdam, The Netherlands.; Department of Sociology, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands., Picavet HSJ; Center for Prevention, Lifestyle and Health, Dutch National Institute for Public Health and the Environment, 3721, Bilthoven, The Netherlands., Verschuren WMM; Center for Prevention, Lifestyle and Health, Dutch National Institute for Public Health and the Environment, 3721, Bilthoven, The Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3584, Utrecht, The Netherlands., Martin NG; Brain and Mental Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Australia., Dolan CV; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Biological Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands., van Loo HM; Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9713, Groningen, The Netherlands., Penninx BWJH; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Psychiatry, Amsterdam UMC location Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Complex Trait Genetics, 1081, Amsterdam, The Netherlands., Hottenga JJ; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands. jhottenga@hbku.edu.qa.; Department of Biological Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands. jhottenga@hbku.edu.qa.; Neurological Disorder Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation, Doha, P.O. Box 5825, Qatar. jhottenga@hbku.edu.qa., Boomsma DI; Department of Complex Trait Genetics, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Jun 02. Date of Electronic Publication: 2026 Jun 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
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  Data: Genetics of major depressive disorder in a homogeneous population with uniform phenotyping.
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  Data: <searchLink fieldCode="AU" term="%22Huider+F%22">Huider F</searchLink>; Department of Complex Trait Genetics, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands. f.huider@vu.nl.; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands. f.huider@vu.nl.; Department of Biological Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands. f.huider@vu.nl.<br /><searchLink fieldCode="AU" term="%22Milaneschi+Y%22">Milaneschi Y</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Psychiatry, Amsterdam UMC location Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Complex Trait Genetics, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pool+R%22">Pool R</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Biological Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Maciel+BAPC%22">Maciel BAPC</searchLink>; Department of Complex Trait Genetics, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gordon+SD%22">Gordon SD</searchLink>; Brain and Mental Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Han+J%22">Han J</searchLink>; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rietman+ML%22">Rietman ML</searchLink>; Center for Prevention, Lifestyle and Health, Dutch National Institute for Public Health and the Environment, 3721, Bilthoven, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kok+AAL%22">Kok AAL</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Psychiatry, Amsterdam UMC location Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.; Department of Epidemiology and Data Science, Amsterdam UMC, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Galesloot+TE%22">Galesloot TE</searchLink>; IQ Health Science Department, Radboud University Medical Center, 6525, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Mitchell+BL%22">Mitchell BL</searchLink>; Brain and Mental Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22't+Hart+LM%22">'t Hart LM</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Epidemiology and Data Science, Amsterdam UMC, 1081, Amsterdam, The Netherlands.; Department of Cell and Chemical Biology, Leiden University Medical Center, 2333, Leiden, The Netherlands.; Department of Biomedical Data Sciences, Section Molecular Epidemiology, Leiden University Medical Center, 2333 ZA, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rutters+F%22">Rutters F</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Epidemiology and Data Science, Amsterdam UMC, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Blom+MT%22">Blom MT</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of General Practice, Amsterdam UMC, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rhebergen+D%22">Rhebergen D</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Psychiatry, Amsterdam UMC location Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Complex Trait Genetics, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Visser+M%22">Visser M</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Brouwer+IA%22">Brouwer IA</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Health Sciences, Faculty of Science, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Feskens+E%22">Feskens E</searchLink>; Division of Human Nutrition and Health, Wageningen University & Research, 6700, Wageningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hartman+CA%22">Hartman CA</searchLink>; Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9713, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Oldehinkel+AJ%22">Oldehinkel AJ</searchLink>; Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9713, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bot+M%22">Bot M</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Psychiatry, Amsterdam UMC location Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Complex Trait Genetics, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Geus+EJC%22">de Geus EJC</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Biological Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kiemeney+LA%22">Kiemeney LA</searchLink>; IQ Health Science Department, Radboud University Medical Center, 6525, Nijmegen, The Netherlands.; Department of Urology and Department for Health Evidence, Radboud University Medical Center, 6525, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Huisman+M%22">Huisman M</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Epidemiology and Data Science, Amsterdam UMC, 1081, Amsterdam, The Netherlands.; Department of Sociology, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Picavet+HSJ%22">Picavet HSJ</searchLink>; Center for Prevention, Lifestyle and Health, Dutch National Institute for Public Health and the Environment, 3721, Bilthoven, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Verschuren+WMM%22">Verschuren WMM</searchLink>; Center for Prevention, Lifestyle and Health, Dutch National Institute for Public Health and the Environment, 3721, Bilthoven, The Netherlands.; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, 3584, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Martin+NG%22">Martin NG</searchLink>; Brain and Mental Health Program, QIMR Berghofer Medical Research Institute, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Dolan+CV%22">Dolan CV</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Biological Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Loo+HM%22">van Loo HM</searchLink>; Department of Psychiatry, University of Groningen, University Medical Center Groningen, 9713, Groningen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Penninx+BWJH%22">Penninx BWJH</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.; Department of Psychiatry, Amsterdam UMC location Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.; Amsterdam Neuroscience, Complex Trait Genetics, 1081, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hottenga+JJ%22">Hottenga JJ</searchLink>; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands. jhottenga@hbku.edu.qa.; Department of Biological Psychology, Faculty of Behavioral and Movement Sciences, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands. jhottenga@hbku.edu.qa.; Neurological Disorder Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Qatar Foundation, Doha, P.O. Box 5825, Qatar. jhottenga@hbku.edu.qa.<br /><searchLink fieldCode="AU" term="%22Boomsma+DI%22">Boomsma DI</searchLink>; Department of Complex Trait Genetics, Vrije Universiteit Amsterdam, 1081, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
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