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NETosis associates with human TB lung tissue destruction and disease pathogenesis.

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Title: NETosis associates with human TB lung tissue destruction and disease pathogenesis.
Authors: Fisher KL; Africa Health Research Institute, KwaZulu-Natal, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa., Mpotje T; Africa Health Research Institute, KwaZulu-Natal, South Africa., Nargan K; Africa Health Research Institute, KwaZulu-Natal, South Africa., Moodley D; Africa Health Research Institute, KwaZulu-Natal, South Africa., Rajkumar-Bhugeloo K; Africa Health Research Institute, KwaZulu-Natal, South Africa., Baiyegunhi OO; Africa Health Research Institute, KwaZulu-Natal, South Africa.; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa., Naidoo T; Africa Health Research Institute, KwaZulu-Natal, South Africa.; Department of Forensic & Legal Medicine, Walter Sisulu University, Mthatha, Eastern Cape, South Africa., Madansein R; Department of Cardiothoracic Surgery, University of KwaZulu Natal, Inkosi Albert Luthuli Central and King DinuZulu Hospitals, Durban, South Africa., Sathekge M; Nuclear Medicine Research Infrastructure (NuMeRI), Department of Nuclear Medicine, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South Africa., Leslie A; Africa Health Research Institute, KwaZulu-Natal, South Africa.; Division of Infection and Immunity, University College London, London, United Kingdom., Tomlinson G; Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, United Kingdom., Pollara G; Division of Infection and Immunity, University College London, London, United Kingdom., Noursadeghi M; Division of Infection and Immunity, University College London, London, United Kingdom., Steyn AJC; Africa Health Research Institute, KwaZulu-Natal, South Africa.; Department of Microbiology, Centres for AIDS Research and Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, USA., Ndung'u T; Africa Health Research Institute, KwaZulu-Natal, South Africa.; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.; Division of Infection and Immunity, University College London, London, United Kingdom., Marakalala MJ; Africa Health Research Institute, KwaZulu-Natal, South Africa. mjmarakalala@sun.ac.za.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa. mjmarakalala@sun.ac.za.; Division of Infection and Immunity, University College London, London, United Kingdom. mjmarakalala@sun.ac.za.; South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa. mjmarakalala@sun.ac.za.
Source: EMBO molecular medicine [EMBO Mol Med] 2026 Jul; Vol. 18 (7), pp. 2547-2572. Date of Electronic Publication: 2026 Jun 02.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: NETosis associates with human TB lung tissue destruction and disease pathogenesis.
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  Data: <searchLink fieldCode="AU" term="%22Fisher+KL%22">Fisher KL</searchLink>; Africa Health Research Institute, KwaZulu-Natal, South Africa.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Mpotje+T%22">Mpotje T</searchLink>; Africa Health Research Institute, KwaZulu-Natal, South Africa.<br /><searchLink fieldCode="AU" term="%22Nargan+K%22">Nargan K</searchLink>; Africa Health Research Institute, KwaZulu-Natal, South Africa.<br /><searchLink fieldCode="AU" term="%22Moodley+D%22">Moodley D</searchLink>; Africa Health Research Institute, KwaZulu-Natal, South Africa.<br /><searchLink fieldCode="AU" term="%22Rajkumar-Bhugeloo+K%22">Rajkumar-Bhugeloo K</searchLink>; Africa Health Research Institute, KwaZulu-Natal, South Africa.<br /><searchLink fieldCode="AU" term="%22Baiyegunhi+OO%22">Baiyegunhi OO</searchLink>; Africa Health Research Institute, KwaZulu-Natal, South Africa.; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Naidoo+T%22">Naidoo T</searchLink>; Africa Health Research Institute, KwaZulu-Natal, South Africa.; Department of Forensic & Legal Medicine, Walter Sisulu University, Mthatha, Eastern Cape, South Africa.<br /><searchLink fieldCode="AU" term="%22Madansein+R%22">Madansein R</searchLink>; Department of Cardiothoracic Surgery, University of KwaZulu Natal, Inkosi Albert Luthuli Central and King DinuZulu Hospitals, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Sathekge+M%22">Sathekge M</searchLink>; Nuclear Medicine Research Infrastructure (NuMeRI), Department of Nuclear Medicine, University of Pretoria and Steve Biko Academic Hospital, Pretoria, South Africa.<br /><searchLink fieldCode="AU" term="%22Leslie+A%22">Leslie A</searchLink>; Africa Health Research Institute, KwaZulu-Natal, South Africa.; Division of Infection and Immunity, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tomlinson+G%22">Tomlinson G</searchLink>; Clinical Medicine, School of Medicine and Population Health, University of Sheffield, Sheffield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Pollara+G%22">Pollara G</searchLink>; Division of Infection and Immunity, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Noursadeghi+M%22">Noursadeghi M</searchLink>; Division of Infection and Immunity, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Steyn+AJC%22">Steyn AJC</searchLink>; Africa Health Research Institute, KwaZulu-Natal, South Africa.; Department of Microbiology, Centres for AIDS Research and Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, USA.<br /><searchLink fieldCode="AU" term="%22Ndung'u+T%22">Ndung'u T</searchLink>; Africa Health Research Institute, KwaZulu-Natal, South Africa.; HIV Pathogenesis Programme, Doris Duke Medical Research Institute, Nelson R Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa.; Division of Infection and Immunity, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Marakalala+MJ%22">Marakalala MJ</searchLink>; Africa Health Research Institute, KwaZulu-Natal, South Africa. mjmarakalala@sun.ac.za.; School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa. mjmarakalala@sun.ac.za.; Division of Infection and Immunity, University College London, London, United Kingdom. mjmarakalala@sun.ac.za.; South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa. mjmarakalala@sun.ac.za.
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        Text: English
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