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Multi-omics integration provides biological insight and prioritizes potential drug targets in multiple sclerosis progression.

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Title: Multi-omics integration provides biological insight and prioritizes potential drug targets in multiple sclerosis progression.
Authors: Jiang Y; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden. yuan.jiang@ki.se., Xiao J; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden.; Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, 610041, Chengdu, China., Kockum I; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden., Stridh P; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden., Liu Q; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden., Olsson T; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden., Alfredsson L; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden.; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 17177, Sweden., Jiang X; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden. xia.jiang@ki.se.; Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, 610041, Chengdu, China. xia.jiang@ki.se.
Source: Journal of neuroinflammation [J Neuroinflammation] 2026 Jun 02; Vol. 23 (1). Date of Electronic Publication: 2026 Jun 02.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multi-omics integration provides biological insight and prioritizes potential drug targets in multiple sclerosis progression.
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  Data: <searchLink fieldCode="AU" term="%22Jiang+Y%22">Jiang Y</searchLink>; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden. yuan.jiang@ki.se.<br /><searchLink fieldCode="AU" term="%22Xiao+J%22">Xiao J</searchLink>; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden.; Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, 610041, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Kockum+I%22">Kockum I</searchLink>; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden.<br /><searchLink fieldCode="AU" term="%22Stridh+P%22">Stridh P</searchLink>; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden.<br /><searchLink fieldCode="AU" term="%22Liu+Q%22">Liu Q</searchLink>; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden.<br /><searchLink fieldCode="AU" term="%22Olsson+T%22">Olsson T</searchLink>; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden.<br /><searchLink fieldCode="AU" term="%22Alfredsson+L%22">Alfredsson L</searchLink>; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden.; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 17177, Sweden.<br /><searchLink fieldCode="AU" term="%22Jiang+X%22">Jiang X</searchLink>; Department of Clinical Neuroscience, The Karolinska Neuroimmunology and Multiple Sclerosis Centre, Centre for Molecular Medicine, Karolinska Institutet, Stockholm, 171 77, Sweden. xia.jiang@ki.se.; Department of Epidemiology and Health Statistics, West China School of Public Health and West China Fourth Hospital, Sichuan University, 610041, Chengdu, China. xia.jiang@ki.se.
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  Data: <searchLink fieldCode="JN" term="%22101222974%22">Journal of neuroinflammation</searchLink> [J Neuroinflammation] 2026 Jun 02; Vol. 23 (1). <i>Date of Electronic Publication: </i>2026 Jun 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101222974 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1742-2094 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217422094%22">17422094 </searchLink><i>NLM ISO Abbreviation: </i>J Neuroinflammation <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s12974-026-03895-z
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              Text: 2026 Jun 02
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