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Polymeric lysosome-targeting chimeras for extracellular α-synuclein degradation in Parkinson's disease.

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Title: Polymeric lysosome-targeting chimeras for extracellular α-synuclein degradation in Parkinson's disease.
Authors: Bhattacharya A; Department of Pharmacology, Bengal School of Technology, Sugandha, Delhi Road, Near Chuchura Railway Station, Hooghly, 712102, West Bengal, India. abhattacharya031997@gmail.com., Almohaimeed HM; Department of Basic Science, College of Medicine, Princess Nourah Bint Abdulrahman University, P.O.Box 84428, 11671, Riyadh, Saudi Arabia., Aggad WS; Division of Anatomy, Department of Basic Medical Sciences, College of Medicine, University of Jeddah, 23890, Jeddah, Saudi Arabia., Almars AI; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, 21589, Jeddah, Saudi Arabia.; Editome: Precision Gene Editing Unit, King Fahad Medical Research Center, King Abdulaziz University, 21589, Jeddah, Saudi Arabia., Altowaijri OMA; Department of Obstetrics & Gynecology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia., Waggas HA; Department of Obstetrics & Gynecology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia., Bauthman NM; Department of Obstetrician and Gynecologist, Prince Sultan Medical City (Psmmc), Riyadh, Saudi Arabia., Mohammedsaleh ZM; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, 71491, Tabuk, Saudi Arabia., ALMatrafi TA; Department of Anatomy, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Saleh FM; Department of Medical Microbiology, Faculty of Medicine, University of Tabuk, 71491, Tabuk, Saudi Arabia.; Molecular Microbiology and Infectious Diseases Research Unit, University of Tabuk, 71491, Tabuk, Saudi Arabia., Uti DE; Department of Biochemistry, Research and Publications, Kampala International University, P.O. Box 20000, Kampala, Uganda. dan4uti@gmail.com.; Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, Federal University of Health Sciences, Otukpo, Benue State, Nigeria. dan4uti@gmail.com.
Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2026 Jun 02. Date of Electronic Publication: 2026 Jun 02.
Publication Type: Journal Article; Review
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Polymeric lysosome-targeting chimeras for extracellular α-synuclein degradation in Parkinson's disease.
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  Data: <searchLink fieldCode="AU" term="%22Bhattacharya+A%22">Bhattacharya A</searchLink>; Department of Pharmacology, Bengal School of Technology, Sugandha, Delhi Road, Near Chuchura Railway Station, Hooghly, 712102, West Bengal, India. abhattacharya031997@gmail.com.<br /><searchLink fieldCode="AU" term="%22Almohaimeed+HM%22">Almohaimeed HM</searchLink>; Department of Basic Science, College of Medicine, Princess Nourah Bint Abdulrahman University, P.O.Box 84428, 11671, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Aggad+WS%22">Aggad WS</searchLink>; Division of Anatomy, Department of Basic Medical Sciences, College of Medicine, University of Jeddah, 23890, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Almars+AI%22">Almars AI</searchLink>; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, 21589, Jeddah, Saudi Arabia.; Editome: Precision Gene Editing Unit, King Fahad Medical Research Center, King Abdulaziz University, 21589, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Altowaijri+OMA%22">Altowaijri OMA</searchLink>; Department of Obstetrics & Gynecology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Waggas+HA%22">Waggas HA</searchLink>; Department of Obstetrics & Gynecology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Bauthman+NM%22">Bauthman NM</searchLink>; Department of Obstetrician and Gynecologist, Prince Sultan Medical City (Psmmc), Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Mohammedsaleh+ZM%22">Mohammedsaleh ZM</searchLink>; Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, 71491, Tabuk, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22ALMatrafi+TA%22">ALMatrafi TA</searchLink>; Department of Anatomy, College of Medicine, King Saud University, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Saleh+FM%22">Saleh FM</searchLink>; Department of Medical Microbiology, Faculty of Medicine, University of Tabuk, 71491, Tabuk, Saudi Arabia.; Molecular Microbiology and Infectious Diseases Research Unit, University of Tabuk, 71491, Tabuk, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Uti+DE%22">Uti DE</searchLink>; Department of Biochemistry, Research and Publications, Kampala International University, P.O. Box 20000, Kampala, Uganda. dan4uti@gmail.com.; Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medicine, Federal University of Health Sciences, Otukpo, Benue State, Nigeria. dan4uti@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101610673%22">Acta neuropathologica communications</searchLink> [Acta Neuropathol Commun] 2026 Jun 02. <i>Date of Electronic Publication: </i>2026 Jun 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101610673 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2051-5960 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220515960%22">20515960 </searchLink><i>NLM ISO Abbreviation: </i>Acta Neuropathol Commun <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 02
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