A multimodal evaluation of transcranial photobiomodulation in mild cognitive impairment: Cognitive, metabolic, and neuroimaging outcomes of a pilot randomized controlled trial.

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Title: A multimodal evaluation of transcranial photobiomodulation in mild cognitive impairment: Cognitive, metabolic, and neuroimaging outcomes of a pilot randomized controlled trial.
Authors: Rashidi-Ranjbar N; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada., Churchill NW; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada., Jerkic M; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada., Zomorrodi R; Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto, ON, Canada., Rotstein O; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.; Temerty Faculty of Medicine, Department of Surgery, University of Toronto, Toronto, ON, Canada., Schneider R; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.; Temerty Faculty of Medicine, Division of Neurology, University of Toronto, Toronto, ON, Canada., Andreazza AC; Temerty Faculty of Medicine, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.; Department of Pharmacology & Toxicology, Mitochondrial Innovation Initiative, University of Toronto, Toronto, ON, Canada., Rajji TK; Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, USA., Graham SJ; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Physical Sciences Platform, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada., Munoz DG; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.; Temerty Faculty of Medicine, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Fornazzari L; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada., Lim L; Vielight Inc., Toronto, ON, Canada., Norris M; Temerty Faculty of Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada., Schweizer TA; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.; Temerty Faculty of Medicine, Department of Neurosurgery, University of Toronto, Toronto, ON, Canada., Fischer CE; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.; Temerty Faculty of Medicine, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
Source: Journal of Alzheimer's disease : JAD [J Alzheimers Dis] 2026 Jun 03, pp. 13872877261453911. Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 9814863 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8908 (Electronic) Linking ISSN: 13872877 NLM ISO Abbreviation: J Alzheimers Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Rashidi-Ranjbar+N%22">Rashidi-Ranjbar N</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Churchill+NW%22">Churchill NW</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Jerkic+M%22">Jerkic M</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Zomorrodi+R%22">Zomorrodi R</searchLink>; Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Rotstein+O%22">Rotstein O</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.; Temerty Faculty of Medicine, Department of Surgery, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Schneider+R%22">Schneider R</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.; Temerty Faculty of Medicine, Division of Neurology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Andreazza+AC%22">Andreazza AC</searchLink>; Temerty Faculty of Medicine, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.; Department of Pharmacology & Toxicology, Mitochondrial Innovation Initiative, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Rajji+TK%22">Rajji TK</searchLink>; Temerty Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto, ON, Canada.; Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Graham+SJ%22">Graham SJ</searchLink>; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.; Physical Sciences Platform, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Munoz+DG%22">Munoz DG</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.; Temerty Faculty of Medicine, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Fornazzari+L%22">Fornazzari L</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Lim+L%22">Lim L</searchLink>; Vielight Inc., Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Norris+M%22">Norris M</searchLink>; Temerty Faculty of Medicine, Department of Medicine, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Schweizer+TA%22">Schweizer TA</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.; Temerty Faculty of Medicine, Department of Neurosurgery, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Fischer+CE%22">Fischer CE</searchLink>; Keenan Research Centre for Biomedical Science, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada.; Temerty Faculty of Medicine, Department of Psychiatry, University of Toronto, Toronto, ON, Canada.
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  Data: <searchLink fieldCode="JN" term="%229814863%22">Journal of Alzheimer's disease : JAD</searchLink> [J Alzheimers Dis] 2026 Jun 03, pp. 13872877261453911. <i>Date of Electronic Publication: </i>2026 Jun 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22SAGE+Publications%22">SAGE Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9814863 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1875-8908 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213872877%22">13872877 </searchLink><i>NLM ISO Abbreviation: </i>J Alzheimers Dis <i>Subsets: </i>MEDLINE
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