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Dolutegravir as First- or Second-line Treatment for Children With HIV: 240-Week Follow-up of the ODYSSEY Randomized Trial.

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Title: Dolutegravir as First- or Second-line Treatment for Children With HIV: 240-Week Follow-up of the ODYSSEY Randomized Trial.
Authors: Mujuru HA; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe., White E; UCL Innovative Clinical Trials Unit (former MRC CTU at UCL), Institute of Clinical Trials and Methodology, University College London, London, UK., Kekitiinwa AR; Baylor College of Medicine Children's Foundation Uganda, Kampala, Uganda., Lugemwa A; Joint Clinical Research Centre, Mbarara, Uganda., Kityo C; Joint Clinical Research Centre, Kampala, Uganda., Violari A; Faculty of Health Sciences, Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa., Ahimbisibwe GM; Makerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda., Variava E; Faculty of Health Sciences, Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa., Archary M; Department of Paediatrics, Victoria Mxenge Hospital, Enhancing Care Foundation, Durban, South Africa., Cotton M; Department of Paediatrics and Child Health, Family Center for Research With Ubuntu, Stellenbosch University, Cape Town, South Africa., Ounchanum P; Chiangrai Prachanukroh Hospital, Chiangrai, Thailand., Puthanakit T; HIVNAT Thai Red Cross AIDS Research Center and Department of Pediatrics, Chulalongkorn University, Bangkok, Thailand., Kanjanavanit S; Nakornping Hospital, Chiang Mai, Thailand., Ngampiyaskul C; Prapokklao Hospital, Chanthaburi, Thailand., Kobbe R; Institute for Infection Research and Vaccine Development, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Department of Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany., Bandi S; University Hospitals of Leicester NHS Trust, Leicester, UK., Epalza C; Universidad Complutense, Hospital Universitario 12 de Octubre, Madrid, Spain., Bwakura-Dangarembizi M; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe., Bbuye D; Baylor College of Medicine Children's Foundation Uganda, Kampala, Uganda., Kasozi M; Joint Clinical Research Centre, Mbarara, Uganda., Kaudha E; Joint Clinical Research Centre, Kampala, Uganda., Cressey TR; AMS-PHPT Research Collaboration, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand., Giaquinto C; Fondazione Penta ETS, Padua, Italy.; University of Padua, Padua, Italy., Jafta L; Fondazione Penta ETS, Padua, Italy., Bamford A; UCL Innovative Clinical Trials Unit (former MRC CTU at UCL), Institute of Clinical Trials and Methodology, University College London, London, UK.; Department of Paediatric Infectious Diseases, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.; UCL Great Ormond Street Institute of Child Health, London, UK., Rojo P; Universidad Complutense, Hospital Universitario 12 de Octubre, Madrid, Spain., Gibb DM; UCL Innovative Clinical Trials Unit (former MRC CTU at UCL), Institute of Clinical Trials and Methodology, University College London, London, UK., Turkova A; UCL Innovative Clinical Trials Unit (former MRC CTU at UCL), Institute of Clinical Trials and Methodology, University College London, London, UK., Ford D; UCL Innovative Clinical Trials Unit (former MRC CTU at UCL), Institute of Clinical Trials and Methodology, University College London, London, UK.
Source: Open forum infectious diseases [Open Forum Infect Dis] 2026 May 05; Vol. 13 (5), pp. ofag266. Date of Electronic Publication: 2026 May 05 (Print Publication: 2026).
Publication Type: Clinical Trial; Journal Article
Journal Info: Publisher: Published by Oxford University Press on behalf of the Infectious Diseases Society of America Country of Publication: United States NLM ID: 101637045 Publication Model: eCollection Cited Medium: Print ISSN: 2328-8957 (Print) Linking ISSN: 23288957 NLM ISO Abbreviation: Open Forum Infect Dis Subsets: PubMed not MEDLINE
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  Data: Dolutegravir as First- or Second-line Treatment for Children With HIV: 240-Week Follow-up of the ODYSSEY Randomized Trial.
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  Data: <searchLink fieldCode="AU" term="%22Mujuru+HA%22">Mujuru HA</searchLink>; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe.<br /><searchLink fieldCode="AU" term="%22White+E%22">White E</searchLink>; UCL Innovative Clinical Trials Unit (former MRC CTU at UCL), Institute of Clinical Trials and Methodology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kekitiinwa+AR%22">Kekitiinwa AR</searchLink>; Baylor College of Medicine Children's Foundation Uganda, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Lugemwa+A%22">Lugemwa A</searchLink>; Joint Clinical Research Centre, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Kityo+C%22">Kityo C</searchLink>; Joint Clinical Research Centre, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Violari+A%22">Violari A</searchLink>; Faculty of Health Sciences, Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Ahimbisibwe+GM%22">Ahimbisibwe GM</searchLink>; Makerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Variava+E%22">Variava E</searchLink>; Faculty of Health Sciences, Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa.<br /><searchLink fieldCode="AU" term="%22Archary+M%22">Archary M</searchLink>; Department of Paediatrics, Victoria Mxenge Hospital, Enhancing Care Foundation, Durban, South Africa.<br /><searchLink fieldCode="AU" term="%22Cotton+M%22">Cotton M</searchLink>; Department of Paediatrics and Child Health, Family Center for Research With Ubuntu, Stellenbosch University, Cape Town, South Africa.<br /><searchLink fieldCode="AU" term="%22Ounchanum+P%22">Ounchanum P</searchLink>; Chiangrai Prachanukroh Hospital, Chiangrai, Thailand.<br /><searchLink fieldCode="AU" term="%22Puthanakit+T%22">Puthanakit T</searchLink>; HIVNAT Thai Red Cross AIDS Research Center and Department of Pediatrics, Chulalongkorn University, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Kanjanavanit+S%22">Kanjanavanit S</searchLink>; Nakornping Hospital, Chiang Mai, Thailand.<br /><searchLink fieldCode="AU" term="%22Ngampiyaskul+C%22">Ngampiyaskul C</searchLink>; Prapokklao Hospital, Chanthaburi, Thailand.<br /><searchLink fieldCode="AU" term="%22Kobbe+R%22">Kobbe R</searchLink>; Institute for Infection Research and Vaccine Development, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.; Department of Infectious Disease Epidemiology, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bandi+S%22">Bandi S</searchLink>; University Hospitals of Leicester NHS Trust, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Epalza+C%22">Epalza C</searchLink>; Universidad Complutense, Hospital Universitario 12 de Octubre, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Bwakura-Dangarembizi+M%22">Bwakura-Dangarembizi M</searchLink>; University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe.<br /><searchLink fieldCode="AU" term="%22Bbuye+D%22">Bbuye D</searchLink>; Baylor College of Medicine Children's Foundation Uganda, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Kasozi+M%22">Kasozi M</searchLink>; Joint Clinical Research Centre, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Kaudha+E%22">Kaudha E</searchLink>; Joint Clinical Research Centre, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Cressey+TR%22">Cressey TR</searchLink>; AMS-PHPT Research Collaboration, Department of Medical Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand.<br /><searchLink fieldCode="AU" term="%22Giaquinto+C%22">Giaquinto C</searchLink>; Fondazione Penta ETS, Padua, Italy.; University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Jafta+L%22">Jafta L</searchLink>; Fondazione Penta ETS, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Bamford+A%22">Bamford A</searchLink>; UCL Innovative Clinical Trials Unit (former MRC CTU at UCL), Institute of Clinical Trials and Methodology, University College London, London, UK.; Department of Paediatric Infectious Diseases, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK.; UCL Great Ormond Street Institute of Child Health, London, UK.<br /><searchLink fieldCode="AU" term="%22Rojo+P%22">Rojo P</searchLink>; Universidad Complutense, Hospital Universitario 12 de Octubre, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gibb+DM%22">Gibb DM</searchLink>; UCL Innovative Clinical Trials Unit (former MRC CTU at UCL), Institute of Clinical Trials and Methodology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Turkova+A%22">Turkova A</searchLink>; UCL Innovative Clinical Trials Unit (former MRC CTU at UCL), Institute of Clinical Trials and Methodology, University College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Ford+D%22">Ford D</searchLink>; UCL Innovative Clinical Trials Unit (former MRC CTU at UCL), Institute of Clinical Trials and Methodology, University College London, London, UK.
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  Data: <searchLink fieldCode="JN" term="%22101637045%22">Open forum infectious diseases</searchLink> [Open Forum Infect Dis] 2026 May 05; Vol. 13 (5), pp. ofag266. <i>Date of Electronic Publication: </i>2026 May 05 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Published+by+Oxford+University+Press+on+behalf+of+the+Infectious+Diseases+Society+of+America%22">Published by Oxford University Press on behalf of the Infectious Diseases Society of America </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101637045 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2328-8957 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223288957%22">23288957 </searchLink><i>NLM ISO Abbreviation: </i>Open Forum Infect Dis <i>Subsets: </i>PubMed not MEDLINE
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