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Immune Checkpoint Inhibitor Rechallenge in Unresectable Hepatocellular Carcinoma: A Multicenter Efficacy and Safety Study.

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Title: Immune Checkpoint Inhibitor Rechallenge in Unresectable Hepatocellular Carcinoma: A Multicenter Efficacy and Safety Study.
Authors: Chen JK; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Wei JL; Department of Oncology, First Affiliated Hospital of Guangxi Medical University, Nanning, China., Yang ZD; Department of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China., Liu SP; Department of Hepatobiliary Surgery, Guigang People's Hospital, Guigang, China., Li ZC; Department of Hepatobiliary Surgery, First Clinical Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China., Chen K; Department of Hepatobiliary Surgery, Second Affiliated Hospital of Guangxi Medical University, Nanning, China., Qin C; Department of Hepatobiliary Surgery, Liuzhou People's Hospital, Liuzhou, China., Su Z; Department of Hepatobiliary Surgery, First People's Hospital of Nanning, Nanning, China., Ye L; Department of Hepatobiliary Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China., Li SQ; Department of Hepatobiliary Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China., Liu GX; Department of Hepatobiliary Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China., Meng JY; Department of Hepatobiliary Surgery, Wuzhou Workers' Hospital, Wuzhou, China., Wu YH; Department of Oncology, Wuzhou People's Hospital, Wuzhou, China., Quan T; Department of Oncology, Guidong People's Hospital, Wuzhou, China., Li J; Department of Oncology, Wuzhou Red Cross Hospital, Wuzhou, China., Deng ZJ; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Yang DL; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Su JY; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Chen GL; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Dong CY; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Gu BY; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Li WY; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Qin XS; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Long XQ; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Ma L; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China., Zhong JH; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.; Key Laboratory of Early Prevention and Treatment for Regional High-Frequency Tumors (Guangxi Medical University), Ministry of Education, Nanning, China.; Guangxi Key Laboratory of Early Prevention and Treatment for Regional High-Frequency Tumors, Nanning, China.
Corporate Authors: GUIDANCE investigators
Source: Liver cancer [Liver Cancer] 2026 Mar 20. Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: S. Karger Country of Publication: Switzerland NLM ID: 101597993 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2235-1795 (Print) Linking ISSN: 16645553 NLM ISO Abbreviation: Liver Cancer
Database: MEDLINE Ultimate
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  Data: Immune Checkpoint Inhibitor Rechallenge in Unresectable Hepatocellular Carcinoma: A Multicenter Efficacy and Safety Study.
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  Data: <searchLink fieldCode="AU" term="%22Chen+JK%22">Chen JK</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Wei+JL%22">Wei JL</searchLink>; Department of Oncology, First Affiliated Hospital of Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Yang+ZD%22">Yang ZD</searchLink>; Department of Radiation Oncology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Liu+SP%22">Liu SP</searchLink>; Department of Hepatobiliary Surgery, Guigang People's Hospital, Guigang, China.<br /><searchLink fieldCode="AU" term="%22Li+ZC%22">Li ZC</searchLink>; Department of Hepatobiliary Surgery, First Clinical Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Chen+K%22">Chen K</searchLink>; Department of Hepatobiliary Surgery, Second Affiliated Hospital of Guangxi Medical University, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Qin+C%22">Qin C</searchLink>; Department of Hepatobiliary Surgery, Liuzhou People's Hospital, Liuzhou, China.<br /><searchLink fieldCode="AU" term="%22Su+Z%22">Su Z</searchLink>; Department of Hepatobiliary Surgery, First People's Hospital of Nanning, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Ye+L%22">Ye L</searchLink>; Department of Hepatobiliary Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.<br /><searchLink fieldCode="AU" term="%22Li+SQ%22">Li SQ</searchLink>; Department of Hepatobiliary Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.<br /><searchLink fieldCode="AU" term="%22Liu+GX%22">Liu GX</searchLink>; Department of Hepatobiliary Surgery, Affiliated Hospital of Guilin Medical University, Guilin, China.<br /><searchLink fieldCode="AU" term="%22Meng+JY%22">Meng JY</searchLink>; Department of Hepatobiliary Surgery, Wuzhou Workers' Hospital, Wuzhou, China.<br /><searchLink fieldCode="AU" term="%22Wu+YH%22">Wu YH</searchLink>; Department of Oncology, Wuzhou People's Hospital, Wuzhou, China.<br /><searchLink fieldCode="AU" term="%22Quan+T%22">Quan T</searchLink>; Department of Oncology, Guidong People's Hospital, Wuzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; Department of Oncology, Wuzhou Red Cross Hospital, Wuzhou, China.<br /><searchLink fieldCode="AU" term="%22Deng+ZJ%22">Deng ZJ</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Yang+DL%22">Yang DL</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Su+JY%22">Su JY</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Chen+GL%22">Chen GL</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Dong+CY%22">Dong CY</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Gu+BY%22">Gu BY</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Li+WY%22">Li WY</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Qin+XS%22">Qin XS</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Long+XQ%22">Long XQ</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Ma+L%22">Ma L</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.<br /><searchLink fieldCode="AU" term="%22Zhong+JH%22">Zhong JH</searchLink>; Department of Hepatobiliary Surgery, Guangxi Medical University Cancer Hospital, Nanning, China.; Key Laboratory of Early Prevention and Treatment for Regional High-Frequency Tumors (Guangxi Medical University), Ministry of Education, Nanning, China.; Guangxi Key Laboratory of Early Prevention and Treatment for Regional High-Frequency Tumors, Nanning, China.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22S%2E+Karger%22">S. Karger </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101597993 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2235-1795 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216645553%22">16645553 </searchLink><i>NLM ISO Abbreviation: </i>Liver Cancer
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