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The Comrades Marathon: a narrative review of physiological responses and health implications in the world's oldest ultra-marathon.

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Title: The Comrades Marathon: a narrative review of physiological responses and health implications in the world's oldest ultra-marathon.
Authors: Knechtle B; Medbase St. Gallen Am Vadianplatz, St. Gallen, Switzerland.; Institute of Primary Care, University Hospital Zurich, Zurich, Switzerland., Scheer V; Ultra Sports Science Foundation, Pierre-Bénite, Auvergne-Rhône-Alpes, France., Nikolaidis PT; School of Health and Caring Sciences, University of West Attica, Athens, Greece., Thuany M; Ultra Sports Science Foundation, Pierre-Bénite, Auvergne-Rhône-Alpes, France.; Department of Sports, State University of Pará, Belém, Brazil., Chlíbková D; Centre of Sports Activities, Brno University of Technology, Brno, Czechia., Forte P; Department of Sports, Higher Institute of Educational Sciences of the Douro, Penafiel, Portugal.; Department of Sports Sciences, Instituto Politécnico de Bragança, Bragança, Portugal.; Research Center for Active Living and Wellbeing (Livewell), Instituto Politécnico de Bragança, Bragança, Portugal., Leite LB; Department of Physical Education, Federal University of Viçosa, Viçosa, Brazil., Weiss K; Institute of Primary Care, University Hospital Zurich, Zurich, Switzerland., Rosemann T; Institute of Primary Care, University Hospital Zurich, Zurich, Switzerland., Duric S; American University of the Middle East, Egaila, Kuwait.
Source: Frontiers in physiology [Front Physiol] 2026 May 18; Vol. 17, pp. 1811456. Date of Electronic Publication: 2026 May 18 (Print Publication: 2026).
Publication Type: Journal Article; Systematic Review
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101549006 Publication Model: eCollection Cited Medium: Print ISSN: 1664-042X (Print) Linking ISSN: 1664042X NLM ISO Abbreviation: Front Physiol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: The Comrades Marathon: a narrative review of physiological responses and health implications in the world's oldest ultra-marathon.
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  Data: <searchLink fieldCode="AU" term="%22Knechtle+B%22">Knechtle B</searchLink>; Medbase St. Gallen Am Vadianplatz, St. Gallen, Switzerland.; Institute of Primary Care, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Scheer+V%22">Scheer V</searchLink>; Ultra Sports Science Foundation, Pierre-Bénite, Auvergne-Rhône-Alpes, France.<br /><searchLink fieldCode="AU" term="%22Nikolaidis+PT%22">Nikolaidis PT</searchLink>; School of Health and Caring Sciences, University of West Attica, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Thuany+M%22">Thuany M</searchLink>; Ultra Sports Science Foundation, Pierre-Bénite, Auvergne-Rhône-Alpes, France.; Department of Sports, State University of Pará, Belém, Brazil.<br /><searchLink fieldCode="AU" term="%22Chlíbková+D%22">Chlíbková D</searchLink>; Centre of Sports Activities, Brno University of Technology, Brno, Czechia.<br /><searchLink fieldCode="AU" term="%22Forte+P%22">Forte P</searchLink>; Department of Sports, Higher Institute of Educational Sciences of the Douro, Penafiel, Portugal.; Department of Sports Sciences, Instituto Politécnico de Bragança, Bragança, Portugal.; Research Center for Active Living and Wellbeing (Livewell), Instituto Politécnico de Bragança, Bragança, Portugal.<br /><searchLink fieldCode="AU" term="%22Leite+LB%22">Leite LB</searchLink>; Department of Physical Education, Federal University of Viçosa, Viçosa, Brazil.<br /><searchLink fieldCode="AU" term="%22Weiss+K%22">Weiss K</searchLink>; Institute of Primary Care, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rosemann+T%22">Rosemann T</searchLink>; Institute of Primary Care, University Hospital Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Duric+S%22">Duric S</searchLink>; American University of the Middle East, Egaila, Kuwait.
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  Data: <searchLink fieldCode="JN" term="%22101549006%22">Frontiers in physiology</searchLink> [Front Physiol] 2026 May 18; Vol. 17, pp. 1811456. <i>Date of Electronic Publication: </i>2026 May 18 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation%22">Frontiers Research Foundation </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101549006 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1664-042X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221664042X%22">1664042X </searchLink><i>NLM ISO Abbreviation: </i>Front Physiol <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 May 18
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