CIDEB and CGI-58 differentially regulate liver lipid-droplet cholesterol to modulate metabolic dysfunction-associated steatohepatitis severity.
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| Title: | CIDEB and CGI-58 differentially regulate liver lipid-droplet cholesterol to modulate metabolic dysfunction-associated steatohepatitis severity. |
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| Authors: | Sakuma I; Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA; Departments of Molecular Diagnosis, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan. Electronic address: ikki.sakuma@yale.edu., Gaspar RC; Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA., Morgan HN; Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA., Zheng J; Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA., Nasiri AR; Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA., Dufour S; Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA., Kahn M; Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA., Guerra MT; Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA., Taki Y; Departments of Molecular Diagnosis, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan., Kawashima Y; Kazusa DNA Research Institute, Chiba 292-0818, Japan., Yimlamai D; Departments of Pediatrics, Yale School of Medicine, New Haven, CT 06520, USA., Perelis M; Ionis Pharmaceuticals, Carlsbad, CA, USA., Vatner DF; Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA., Petersen KF; Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA., Samuel VT; Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA; West Haven VA Medical Center, West Haven, CT, USA., Tanaka T; Departments of Molecular Diagnosis, Chiba University Graduate School of Medicine, Chiba 260-8670, Japan., Shulman GI; Departments of Internal Medicine, Yale School of Medicine, New Haven, CT 06520, USA; Departments of Cellular & Molecular Physiology, Yale School of Medicine, New Haven, CT 06520, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA. Electronic address: gerald.shulman@yale.edu. |
| Source: | Cell reports [Cell Rep] 2026 Jun 23; Vol. 45 (6), pp. 117369. Date of Electronic Publication: 2026 Jun 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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