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Type I interferon signaling in hematopoietic cells impairs neutrophil antibacterial function in the middle ear during viral co-infection.

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Title: Type I interferon signaling in hematopoietic cells impairs neutrophil antibacterial function in the middle ear during viral co-infection.
Authors: Shaw SC; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA., Jamil TL; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA., Heslop G; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA., Fleck JT; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA., Johnson W; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA., Lorenz BP; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA., Drigot Z; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA., Harris JK; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA., Gitomer SA; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA; Children's Hospital Colorado, Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA., Clark SE; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address: sarah.e.clark@cuanschutz.edu.
Source: Cell reports. Medicine [Cell Rep Med] 2026 Jun 16; Vol. 7 (6), pp. 102846. Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE
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  Data: Type I interferon signaling in hematopoietic cells impairs neutrophil antibacterial function in the middle ear during viral co-infection.
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  Data: <searchLink fieldCode="AU" term="%22Shaw+SC%22">Shaw SC</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Jamil+TL%22">Jamil TL</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Heslop+G%22">Heslop G</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Fleck+JT%22">Fleck JT</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+W%22">Johnson W</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Lorenz+BP%22">Lorenz BP</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Drigot+Z%22">Drigot Z</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Harris+JK%22">Harris JK</searchLink>; Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Gitomer+SA%22">Gitomer SA</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA; Children's Hospital Colorado, Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA.<br /><searchLink fieldCode="AU" term="%22Clark+SE%22">Clark SE</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Colorado School of Medicine, Aurora, CO 80045, USA. Electronic address: sarah.e.clark@cuanschutz.edu.
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  Data: <searchLink fieldCode="JN" term="%22101766894%22">Cell reports. Medicine</searchLink> [Cell Rep Med] 2026 Jun 16; Vol. 7 (6), pp. 102846. <i>Date of Electronic Publication: </i>2026 Jun 03.
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              Text: 2026 Jun 16
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