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Emergency Department-initiated standard versus high-dose buprenorphine induction (ENVISION): a randomised clinical trial protocol.

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Title: Emergency Department-initiated standard versus high-dose buprenorphine induction (ENVISION): a randomised clinical trial protocol.
Authors: Hawk K; Department of Emerency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA kathryn.hawk@yale.edu., Herring A; Department of Emergency Medicine, Highland Hospital, Oakland, California, USA., Chawarski M; Department of Emerency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA., Anderson ES; Department of Emergency Medicine, Highland Hospital, Oakland, California, USA., Baumann M; Department of Emergency Medicine, Maine Medical Center, Portland, Maine, USA., Dorey A; Department of Emergency Medicine, The University of Utah School of Medicine, Salt Lake City, Utah, USA., Holtyn AF; National Institute on Drug Abuse Clinical Trials Network, Gaithersburg, Maryland, USA., Jones C; Department of Emergency Medicine, Cooper Medical School of Rowan University, Camden, New Jersey, USA., Martel S; Department of Emerency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Owens P; Department of Emerency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA., Kmiecik K; The Emmes Corporation, Rockville, Maryland, USA., Strout TD; Department of Emergency Medicine, Maine Medical Center, Portland, Maine, USA., Taillac P; Department of Emergency Medicine, The University of Utah School of Medicine, Salt Lake City, Utah, USA., Lofwall M; Center on Drug and Alcohol Research, University of Kentucky, Lexington, Kentucky, USA., Walsh SL; Center on Drug and Alcohol Research, University of Kentucky, Lexington, Kentucky, USA., D'Onofrio G; Department of Emerency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
Source: BMJ open [BMJ Open] 2026 Jun 03; Vol. 16 (6), pp. e113762. Date of Electronic Publication: 2026 Jun 03.
Publication Type: Journal Article
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
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  Data: Emergency Department-initiated standard versus high-dose buprenorphine induction (ENVISION): a randomised clinical trial protocol.
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  Data: <searchLink fieldCode="AU" term="%22Hawk+K%22">Hawk K</searchLink>; Department of Emerency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA kathryn.hawk@yale.edu.<br /><searchLink fieldCode="AU" term="%22Herring+A%22">Herring A</searchLink>; Department of Emergency Medicine, Highland Hospital, Oakland, California, USA.<br /><searchLink fieldCode="AU" term="%22Chawarski+M%22">Chawarski M</searchLink>; Department of Emerency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.; Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+ES%22">Anderson ES</searchLink>; Department of Emergency Medicine, Highland Hospital, Oakland, California, USA.<br /><searchLink fieldCode="AU" term="%22Baumann+M%22">Baumann M</searchLink>; Department of Emergency Medicine, Maine Medical Center, Portland, Maine, USA.<br /><searchLink fieldCode="AU" term="%22Dorey+A%22">Dorey A</searchLink>; Department of Emergency Medicine, The University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Holtyn+AF%22">Holtyn AF</searchLink>; National Institute on Drug Abuse Clinical Trials Network, Gaithersburg, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Jones+C%22">Jones C</searchLink>; Department of Emergency Medicine, Cooper Medical School of Rowan University, Camden, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Martel+S%22">Martel S</searchLink>; Department of Emerency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Owens+P%22">Owens P</searchLink>; Department of Emerency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Kmiecik+K%22">Kmiecik K</searchLink>; The Emmes Corporation, Rockville, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Strout+TD%22">Strout TD</searchLink>; Department of Emergency Medicine, Maine Medical Center, Portland, Maine, USA.<br /><searchLink fieldCode="AU" term="%22Taillac+P%22">Taillac P</searchLink>; Department of Emergency Medicine, The University of Utah School of Medicine, Salt Lake City, Utah, USA.<br /><searchLink fieldCode="AU" term="%22Lofwall+M%22">Lofwall M</searchLink>; Center on Drug and Alcohol Research, University of Kentucky, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Walsh+SL%22">Walsh SL</searchLink>; Center on Drug and Alcohol Research, University of Kentucky, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22D'Onofrio+G%22">D'Onofrio G</searchLink>; Department of Emerency Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
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