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NeuroPupil: A generalization-first framework for scalable and biologically informative cross-species pupillometry.

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Title: NeuroPupil: A generalization-first framework for scalable and biologically informative cross-species pupillometry.
Authors: Ozdemirli K; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Department of Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, OH 44106., Connor T; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Department of Chemical and Biomedical Engineering, Cleveland State University, Cleveland, OH, 44115., Dinc B; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Department of Computer Sciences, Cleveland State University, Cleveland, OH, 44115., Kim K; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Department of Computer and Data Sciences, Case Western Reserve University, Cleveland, OH 44106., Lacin ME; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195., Maldonado M; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Department of Computer and Data Sciences, Case Western Reserve University, Cleveland, OH 44106., Guha S; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106., Hawk K; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195., Oksuz C; Department of Computer and Data Sciences, Case Western Reserve University, Cleveland, OH 44106., Bell F; Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106., Zhang Z; Department of Computer and Data Sciences, Case Western Reserve University, Cleveland, OH 44106., Leal TP; Department of Genomic Medicine, Cleveland Clinic Research Institute, Cleveland, OH 44195., Sarn N; Department of Genomic Medicine, Cleveland Clinic Research Institute, Cleveland, OH 44195., Sloan A; Department of Cancer Sciences and Translational Oncology, Cleveland Clinic Research, Cleveland, OH 44195., Chomyk A; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195., Ghasia F; Department of Ophthalmology, Cole Eye Institute, Cleveland Clinic, Cleveland, OH 44195., Trapp B; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195., Mata I; Department of Genomic Medicine, Cleveland Clinic Research Institute, Cleveland, OH 44195., Lathia JD; Department of Cancer Sciences and Translational Oncology, Cleveland Clinic Research, Cleveland, OH 44195.; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106.; Rose Ella Burkhardt Brain Tumor & Neuro-Oncology Center, Cleveland Clinic, Cleveland, OH, USA.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Eng C; Department of Genomic Medicine, Cleveland Clinic Research Institute, Cleveland, OH 44195., Yildirim M; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 18. Date of Electronic Publication: 2026 May 18.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Ozdemirli+K%22">Ozdemirli K</searchLink>; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Department of Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, OH 44106.<br /><searchLink fieldCode="AU" term="%22Connor+T%22">Connor T</searchLink>; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Department of Chemical and Biomedical Engineering, Cleveland State University, Cleveland, OH, 44115.<br /><searchLink fieldCode="AU" term="%22Dinc+B%22">Dinc B</searchLink>; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Department of Computer Sciences, Cleveland State University, Cleveland, OH, 44115.<br /><searchLink fieldCode="AU" term="%22Kim+K%22">Kim K</searchLink>; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Department of Computer and Data Sciences, Case Western Reserve University, Cleveland, OH 44106.<br /><searchLink fieldCode="AU" term="%22Lacin+ME%22">Lacin ME</searchLink>; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.<br /><searchLink fieldCode="AU" term="%22Maldonado+M%22">Maldonado M</searchLink>; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Department of Computer and Data Sciences, Case Western Reserve University, Cleveland, OH 44106.<br /><searchLink fieldCode="AU" term="%22Guha+S%22">Guha S</searchLink>; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106.<br /><searchLink fieldCode="AU" term="%22Hawk+K%22">Hawk K</searchLink>; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.<br /><searchLink fieldCode="AU" term="%22Oksuz+C%22">Oksuz C</searchLink>; Department of Computer and Data Sciences, Case Western Reserve University, Cleveland, OH 44106.<br /><searchLink fieldCode="AU" term="%22Bell+F%22">Bell F</searchLink>; Department of Neurosciences, Case Western Reserve University, Cleveland, OH 44106.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; Department of Computer and Data Sciences, Case Western Reserve University, Cleveland, OH 44106.<br /><searchLink fieldCode="AU" term="%22Leal+TP%22">Leal TP</searchLink>; Department of Genomic Medicine, Cleveland Clinic Research Institute, Cleveland, OH 44195.<br /><searchLink fieldCode="AU" term="%22Sarn+N%22">Sarn N</searchLink>; Department of Genomic Medicine, Cleveland Clinic Research Institute, Cleveland, OH 44195.<br /><searchLink fieldCode="AU" term="%22Sloan+A%22">Sloan A</searchLink>; Department of Cancer Sciences and Translational Oncology, Cleveland Clinic Research, Cleveland, OH 44195.<br /><searchLink fieldCode="AU" term="%22Chomyk+A%22">Chomyk A</searchLink>; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.<br /><searchLink fieldCode="AU" term="%22Ghasia+F%22">Ghasia F</searchLink>; Department of Ophthalmology, Cole Eye Institute, Cleveland Clinic, Cleveland, OH 44195.<br /><searchLink fieldCode="AU" term="%22Trapp+B%22">Trapp B</searchLink>; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.<br /><searchLink fieldCode="AU" term="%22Mata+I%22">Mata I</searchLink>; Department of Genomic Medicine, Cleveland Clinic Research Institute, Cleveland, OH 44195.<br /><searchLink fieldCode="AU" term="%22Lathia+JD%22">Lathia JD</searchLink>; Department of Cancer Sciences and Translational Oncology, Cleveland Clinic Research, Cleveland, OH 44195.; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106.; Rose Ella Burkhardt Brain Tumor & Neuro-Oncology Center, Cleveland Clinic, Cleveland, OH, USA.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Eng+C%22">Eng C</searchLink>; Department of Genomic Medicine, Cleveland Clinic Research Institute, Cleveland, OH 44195.<br /><searchLink fieldCode="AU" term="%22Yildirim+M%22">Yildirim M</searchLink>; Department of Neurosciences, Cleveland Clinic Research, Cleveland, OH 44195.; Case Comprehensive Cancer Center, Case Western Reserve University, Cleveland, OH 44106.
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