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Cefepime pharmacokinetics in critically ill children with multiple organ dysfunction syndrome using volumetric absorptive microsampling.

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Title: Cefepime pharmacokinetics in critically ill children with multiple organ dysfunction syndrome using volumetric absorptive microsampling.
Authors: Amajor V; Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Bwint A; Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA., Shein SL; Division of Critical Care Medicine, Rainbow Babies and Children's Hospital, Cleveland, Ohio, USA., Hume J; Division of Critical Care Medicine, University of Minnesota Masonic Children's Hospital, Minneapolis, Minnesota, USA., Rowan CM; Division of Critical Care Medicine, Indiana University School of Medicine at Riley Children's Health, Indianapolis, Indiana, USA., Flygt LP; Division of Critical Care Medicine, University of Iowa Stead Family Children's Hospital, Iowa City, Iowa, USA., Malone MP; Division of Critical Care Medicine, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, Arkansas, USA., Stenson EK; Division of Critical Care Medicine, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado, USA., Weiss SL; Division of Critical Care Medicine, Department of Pediatrics, Nemours Children's Hospital, Wilmington, Delaware, USA.; Department of Pediatrics and Pathology & Genomic Medicine, Sidney Kimmel Medical Center at Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Zinter MS; Division of Critical Care Medicine, University of California-San Francisco Benioff Children's Hospitals, San Francisco, California, USA., Kannan S; Division of Pediatric Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Dahmer MK; Division of Pediatric Critical Care Medicine, University of Michigan C.S. Mott Children's Hospital, Ann Arbor, Michigan, USA., Nofziger RA; Division of Critical Care Medicine, Akron Children's Hospital, Akron, Ohio, USA., Pai MP; PK Core Laboratory, College of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA., Zuppa AF; Department of Pediatrics, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Rhodes NJ; Pharmacometric Center of Excellence, Midwestern University, Downers Grove, Illinois, USA., Hall MW; Division of Critical Care Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA., Scheetz MH; Pharmacometric Center of Excellence, Midwestern University, Downers Grove, Illinois, USA., Downes KJ; Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Pediatrics, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Corporate Authors: Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network
Source: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2026 Jul; Vol. 70 (7), pp. e0173625. Date of Electronic Publication: 2026 Jun 04.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: American Society for Microbiology Country of Publication: United States NLM ID: 0315061 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-6596 (Electronic) Linking ISSN: 00664804 NLM ISO Abbreviation: Antimicrob Agents Chemother Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cefepime pharmacokinetics in critically ill children with multiple organ dysfunction syndrome using volumetric absorptive microsampling.
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  Data: <searchLink fieldCode="AU" term="%22Amajor+V%22">Amajor V</searchLink>; Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Bwint+A%22">Bwint A</searchLink>; Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Shein+SL%22">Shein SL</searchLink>; Division of Critical Care Medicine, Rainbow Babies and Children's Hospital, Cleveland, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Hume+J%22">Hume J</searchLink>; Division of Critical Care Medicine, University of Minnesota Masonic Children's Hospital, Minneapolis, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Rowan+CM%22">Rowan CM</searchLink>; Division of Critical Care Medicine, Indiana University School of Medicine at Riley Children's Health, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Flygt+LP%22">Flygt LP</searchLink>; Division of Critical Care Medicine, University of Iowa Stead Family Children's Hospital, Iowa City, Iowa, USA.<br /><searchLink fieldCode="AU" term="%22Malone+MP%22">Malone MP</searchLink>; Division of Critical Care Medicine, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, Arkansas, USA.<br /><searchLink fieldCode="AU" term="%22Stenson+EK%22">Stenson EK</searchLink>; Division of Critical Care Medicine, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado, USA.<br /><searchLink fieldCode="AU" term="%22Weiss+SL%22">Weiss SL</searchLink>; Division of Critical Care Medicine, Department of Pediatrics, Nemours Children's Hospital, Wilmington, Delaware, USA.; Department of Pediatrics and Pathology & Genomic Medicine, Sidney Kimmel Medical Center at Thomas Jefferson University, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Zinter+MS%22">Zinter MS</searchLink>; Division of Critical Care Medicine, University of California-San Francisco Benioff Children's Hospitals, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Kannan+S%22">Kannan S</searchLink>; Division of Pediatric Critical Care Medicine, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Dahmer+MK%22">Dahmer MK</searchLink>; Division of Pediatric Critical Care Medicine, University of Michigan C.S. Mott Children's Hospital, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Nofziger+RA%22">Nofziger RA</searchLink>; Division of Critical Care Medicine, Akron Children's Hospital, Akron, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Pai+MP%22">Pai MP</searchLink>; PK Core Laboratory, College of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Zuppa+AF%22">Zuppa AF</searchLink>; Department of Pediatrics, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Rhodes+NJ%22">Rhodes NJ</searchLink>; Pharmacometric Center of Excellence, Midwestern University, Downers Grove, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Hall+MW%22">Hall MW</searchLink>; Division of Critical Care Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA.<br /><searchLink fieldCode="AU" term="%22Scheetz+MH%22">Scheetz MH</searchLink>; Pharmacometric Center of Excellence, Midwestern University, Downers Grove, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Downes+KJ%22">Downes KJ</searchLink>; Division of Infectious Diseases, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.; Department of Pediatrics, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
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  Data: <searchLink fieldCode="CA" term="%22Pediatric+Acute+Lung+Injury+and+Sepsis+Investigators+%28PALISI%29+Network%22">Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network</searchLink>
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  Data: <searchLink fieldCode="JN" term="%220315061%22">Antimicrobial agents and chemotherapy</searchLink> [Antimicrob Agents Chemother] 2026 Jul; Vol. 70 (7), pp. e0173625. <i>Date of Electronic Publication: </i>2026 Jun 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Microbiology%22">American Society for Microbiology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0315061 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1098-6596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200664804%22">00664804 </searchLink><i>NLM ISO Abbreviation: </i>Antimicrob Agents Chemother <i>Subsets: </i>MEDLINE
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              Text: 2026 Jul
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