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Targeting GSTZ1 Sensitizes KRASG12C-Mutant Lung Cancer Cells by Overcoming Glutathione and Glycolysis Pathway Rewiring.

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Title: Targeting GSTZ1 Sensitizes KRASG12C-Mutant Lung Cancer Cells by Overcoming Glutathione and Glycolysis Pathway Rewiring.
Authors: Liao Y; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida., Li X; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida., Liu M; Proteomics and Metabolomics Core, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida., Fernandes VC; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida., Duckett D; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida., Haura EB; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida., Monastyrskyi A; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida., Rix U; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.; Department of Molecular Biosciences, University of South Florida, Tampa, Florida.
Source: Cancer research communications [Cancer Res Commun] 2026 Jun 01; Vol. 6 (6), pp. 1376-1387.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Liao+Y%22">Liao Y</searchLink>; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Proteomics and Metabolomics Core, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Fernandes+VC%22">Fernandes VC</searchLink>; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Duckett+D%22">Duckett D</searchLink>; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Haura+EB%22">Haura EB</searchLink>; Department of Thoracic Oncology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Monastyrskyi+A%22">Monastyrskyi A</searchLink>; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.<br /><searchLink fieldCode="AU" term="%22Rix+U%22">Rix U</searchLink>; Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida.; Department of Molecular Biosciences, University of South Florida, Tampa, Florida.
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  Data: <searchLink fieldCode="JN" term="%229918281580506676%22">Cancer research communications</searchLink> [Cancer Res Commun] 2026 Jun 01; Vol. 6 (6), pp. 1376-1387.
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        Value: 10.1158/2767-9764.CRC-25-0698
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        Text: English
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      – TitleFull: Targeting GSTZ1 Sensitizes KRASG12C-Mutant Lung Cancer Cells by Overcoming Glutathione and Glycolysis Pathway Rewiring.
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              Text: 2026 Jun 01
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              Y: 2026
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