Hydroxyapatite composite sodium hyaluronate for alveolar ridge preservation: a prospective, randomized, parallel-controlled, single-blind, non-inferiority multicenter clinical trial.

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Title: Hydroxyapatite composite sodium hyaluronate for alveolar ridge preservation: a prospective, randomized, parallel-controlled, single-blind, non-inferiority multicenter clinical trial.
Authors: Xue Y; National Clinical Research Center for Oral Diseases, State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi'an, China., Liu L; Engineering Research Center of Western Resource Innovation Medicine Green Manufacturing, Shaanxi Key Laboratory of Biomaterials and Synthetic Biology, Shaanxi R&D Center of Biomaterials and Fermentation Engineering, Xi'an Innovative R&D Platform for New Biomedical Materials, Biotech. & Biomed. Research Institute, School of Chemical Engineering, Northwest University, Shaanxi Giant Biotechnology Co., Xi'an, China., Xue C; Department of Stomatology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China., Sun Y; Department of Periodontology, Affiliated Stomatological Hospital, Nanjing Medical University, Nanjing, China., Wang B; Department of Oral Mucosal Diseases, Hospital of Stomatology, Xi'an Jiaotong University, Xi'an, China., Meng J; Department of Stomatology, Xuzhou Central Hospital (Southeast University Affiliated Hospital), Xuzhou, China., Zhou H; National Clinical Research Center for Oral Diseases, State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi'an, China. hongzhi.zhou@foxmail.com.
Source: Clinical oral investigations [Clin Oral Investig] 2026 Jun 04; Vol. 30 (6). Date of Electronic Publication: 2026 Jun 04.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Equivalence Trial
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 9707115 Publication Model: Electronic Cited Medium: Internet ISSN: 1436-3771 (Electronic) Linking ISSN: 14326981 NLM ISO Abbreviation: Clin Oral Investig Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Hydroxyapatite composite sodium hyaluronate for alveolar ridge preservation: a prospective, randomized, parallel-controlled, single-blind, non-inferiority multicenter clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Xue+Y%22">Xue Y</searchLink>; National Clinical Research Center for Oral Diseases, State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Liu+L%22">Liu L</searchLink>; Engineering Research Center of Western Resource Innovation Medicine Green Manufacturing, Shaanxi Key Laboratory of Biomaterials and Synthetic Biology, Shaanxi R&D Center of Biomaterials and Fermentation Engineering, Xi'an Innovative R&D Platform for New Biomedical Materials, Biotech. & Biomed. Research Institute, School of Chemical Engineering, Northwest University, Shaanxi Giant Biotechnology Co., Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Xue+C%22">Xue C</searchLink>; Department of Stomatology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; Department of Periodontology, Affiliated Stomatological Hospital, Nanjing Medical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; Department of Oral Mucosal Diseases, Hospital of Stomatology, Xi'an Jiaotong University, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Meng+J%22">Meng J</searchLink>; Department of Stomatology, Xuzhou Central Hospital (Southeast University Affiliated Hospital), Xuzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+H%22">Zhou H</searchLink>; National Clinical Research Center for Oral Diseases, State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Shaanxi Clinical Research Center for Oral Diseases, Department of Oral and Maxillofacial Surgery, School of Stomatology, The Fourth Military Medical University, Xi'an, China. hongzhi.zhou@foxmail.com.
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  Data: <searchLink fieldCode="JN" term="%229707115%22">Clinical oral investigations</searchLink> [Clin Oral Investig] 2026 Jun 04; Vol. 30 (6). <i>Date of Electronic Publication: </i>2026 Jun 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%22">Springer-Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>9707115 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1436-3771 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214326981%22">14326981 </searchLink><i>NLM ISO Abbreviation: </i>Clin Oral Investig <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00784-026-06921-9
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        Text: English
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      – TitleFull: Hydroxyapatite composite sodium hyaluronate for alveolar ridge preservation: a prospective, randomized, parallel-controlled, single-blind, non-inferiority multicenter clinical trial.
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              Text: 2026 Jun 04
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              Y: 2026
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