3D chromatin architecture-related genes orchestrate LUAD evolution and therapy resistance: insights from integrative machine learning and spatial single-cell mapping.
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| Title: | 3D chromatin architecture-related genes orchestrate LUAD evolution and therapy resistance: insights from integrative machine learning and spatial single-cell mapping. |
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| Authors: | Jing Y; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Xing Y; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Liu Y; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Zhang N; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Pan Y; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Zhang W; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Zhu C; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Zhong Z; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China., Zhang G; Department of Thoracic Surgery, The First Affiliated Hospital of Henan University, Kaifeng, 475000, Henan, China. kfzgy315@163.com.; Kaifeng Key Laboratory of Translational Medicine for Thoracic Diseases, Kaifeng, 475000, Henan, China. kfzgy315@163.com., Li JC; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China. zjulijicheng@163.com.; Institute of Cell Biology, Zhejiang University, Hangzhou, 310030, China. zjulijicheng@163.com., Dong X; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China. dongxiaotao@henu.edu.cn.; Department of Thoracic Surgery, The First Affiliated Hospital of Henan University, Kaifeng, 475000, Henan, China. dongxiaotao@henu.edu.cn.; Kaifeng Key Laboratory of Translational Medicine for Thoracic Diseases, Kaifeng, 475000, Henan, China. dongxiaotao@henu.edu.cn.; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China. dongxiaotao@henu.edu.cn. |
| Source: | Functional & integrative genomics [Funct Integr Genomics] 2026 Jun 04; Vol. 26 (1). Date of Electronic Publication: 2026 Jun 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Germany NLM ID: 100939343 Publication Model: Electronic Cited Medium: Internet ISSN: 1438-7948 (Electronic) Linking ISSN: 1438793X NLM ISO Abbreviation: Funct Integr Genomics Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42240917 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: 3D chromatin architecture-related genes orchestrate LUAD evolution and therapy resistance: insights from integrative machine learning and spatial single-cell mapping. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Jing+Y%22">Jing Y</searchLink>; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China.<br /><searchLink fieldCode="AU" term="%22Xing+Y%22">Xing Y</searchLink>; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China.<br /><searchLink fieldCode="AU" term="%22Zhang+N%22">Zhang N</searchLink>; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China.<br /><searchLink fieldCode="AU" term="%22Pan+Y%22">Pan Y</searchLink>; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China.<br /><searchLink fieldCode="AU" term="%22Zhu+C%22">Zhu C</searchLink>; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China.<br /><searchLink fieldCode="AU" term="%22Zhong+Z%22">Zhong Z</searchLink>; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China.<br /><searchLink fieldCode="AU" term="%22Zhang+G%22">Zhang G</searchLink>; Department of Thoracic Surgery, The First Affiliated Hospital of Henan University, Kaifeng, 475000, Henan, China. kfzgy315@163.com.; Kaifeng Key Laboratory of Translational Medicine for Thoracic Diseases, Kaifeng, 475000, Henan, China. kfzgy315@163.com.<br /><searchLink fieldCode="AU" term="%22Li+JC%22">Li JC</searchLink>; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China. zjulijicheng@163.com.; Institute of Cell Biology, Zhejiang University, Hangzhou, 310030, China. zjulijicheng@163.com.<br /><searchLink fieldCode="AU" term="%22Dong+X%22">Dong X</searchLink>; Laboratory of Receptor Gene Regulation and Drug Discovery, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, Henan, China. dongxiaotao@henu.edu.cn.; Department of Thoracic Surgery, The First Affiliated Hospital of Henan University, Kaifeng, 475000, Henan, China. dongxiaotao@henu.edu.cn.; Kaifeng Key Laboratory of Translational Medicine for Thoracic Diseases, Kaifeng, 475000, Henan, China. dongxiaotao@henu.edu.cn.; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, China. dongxiaotao@henu.edu.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22100939343%22">Functional & integrative genomics</searchLink> [Funct Integr Genomics] 2026 Jun 04; Vol. 26 (1). <i>Date of Electronic Publication: </i>2026 Jun 04. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>100939343 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1438-7948 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221438793X%22">1438793X </searchLink><i>NLM ISO Abbreviation: </i>Funct Integr Genomics <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42240917 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10142-026-01914-z Languages: – Code: eng Text: English Titles: – TitleFull: 3D chromatin architecture-related genes orchestrate LUAD evolution and therapy resistance: insights from integrative machine learning and spatial single-cell mapping. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Jing Y – PersonEntity: Name: NameFull: Xing Y – PersonEntity: Name: NameFull: Liu Y – PersonEntity: Name: NameFull: Zhang N – PersonEntity: Name: NameFull: Pan Y – PersonEntity: Name: NameFull: Zhang W – PersonEntity: Name: NameFull: Zhu C – PersonEntity: Name: NameFull: Zhong Z – PersonEntity: Name: NameFull: Zhang G – PersonEntity: Name: NameFull: Li JC – PersonEntity: Name: NameFull: Dong X IsPartOfRelationships: – BibEntity: Dates: – D: 04 M: 06 Text: 2026 Jun 04 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1438-7948 Numbering: – Type: volume Value: 26 – Type: issue Value: 1 Titles: – TitleFull: Functional & integrative genomics Type: main |
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