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Methylglyoxal engages aging-associated mechanisms to cause filtration impairment in nephrocytes.

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Title: Methylglyoxal engages aging-associated mechanisms to cause filtration impairment in nephrocytes.
Authors: Cheng L; Graduate Institute of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan., Yeh WJ; Graduate Institute of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Program of Nutrition Science, School of Life Science, National Taiwan Normal University, Taipei, Taiwan., Chang FC; Renal Division, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Tang HW; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore., Chan CC; Graduate Institute of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan., Lin SL; Graduate Institute of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Renal Division, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan., Huang SY; Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan. shuyih@ntuh.gov.tw.
Source: Npj aging [NPJ Aging] 2026 Jun 04. Date of Electronic Publication: 2026 Jun 04.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: England NLM ID: 9918402285106676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2731-6068 (Electronic) Linking ISSN: 27316068 NLM ISO Abbreviation: NPJ Aging
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: <searchLink fieldCode="AU" term="%22Cheng+L%22">Cheng L</searchLink>; Graduate Institute of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+WJ%22">Yeh WJ</searchLink>; Graduate Institute of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Program of Nutrition Science, School of Life Science, National Taiwan Normal University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+FC%22">Chang FC</searchLink>; Renal Division, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tang+HW%22">Tang HW</searchLink>; Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Chan+CC%22">Chan CC</searchLink>; Graduate Institute of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Research Center for Developmental Biology and Regenerative Medicine, National Taiwan University, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+SL%22">Lin SL</searchLink>; Graduate Institute of Physiology, College of Medicine, National Taiwan University, Taipei, Taiwan.; Renal Division, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+SY%22">Huang SY</searchLink>; Department of Medical Research, National Taiwan University Hospital, Taipei, Taiwan. shuyih@ntuh.gov.tw.
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  Data: <searchLink fieldCode="JN" term="%229918402285106676%22">Npj aging</searchLink> [NPJ Aging] 2026 Jun 04. <i>Date of Electronic Publication: </i>2026 Jun 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Nature%22">Springer Nature </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9918402285106676 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2731-6068 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2227316068%22">27316068 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Aging
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      – Type: doi
        Value: 10.1038/s41514-026-00369-7
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              Text: 2026 Jun 04
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              Y: 2026
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