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Target RNA-triggered CRISPR-Cas12a2 Preferentially Cleaves Collateral DNA over RNA.

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Title: Target RNA-triggered CRISPR-Cas12a2 Preferentially Cleaves Collateral DNA over RNA.
Authors: Kunwar S; Department of Chemistry and Biochemistry, Utah State University, Logan, UT, USA.; These authors contributed equally., Hallmark T; Department of Chemistry and Biochemistry, Utah State University, Logan, UT, USA.; These authors contributed equally., Manna S; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), Würzburg, Germany., Keiser D; Department of Chemistry and Biochemistry, Utah State University, Logan, UT, USA., Naegle B; Department of Chemistry and Biochemistry, Utah State University, Logan, UT, USA., Thomas A; College of Agriculture and Applied Sciences, Utah State University, Logan, UT, USA., Beisel CL; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), Würzburg, Germany.; Medical Faculty, University of Würzburg, Würzburg, Germany., Jackson RN; Department of Chemistry and Biochemistry, Utah State University, Logan, UT, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 30. Date of Electronic Publication: 2026 May 30.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kunwar+S%22">Kunwar S</searchLink>; Department of Chemistry and Biochemistry, Utah State University, Logan, UT, USA.; These authors contributed equally.<br /><searchLink fieldCode="AU" term="%22Hallmark+T%22">Hallmark T</searchLink>; Department of Chemistry and Biochemistry, Utah State University, Logan, UT, USA.; These authors contributed equally.<br /><searchLink fieldCode="AU" term="%22Manna+S%22">Manna S</searchLink>; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Keiser+D%22">Keiser D</searchLink>; Department of Chemistry and Biochemistry, Utah State University, Logan, UT, USA.<br /><searchLink fieldCode="AU" term="%22Naegle+B%22">Naegle B</searchLink>; Department of Chemistry and Biochemistry, Utah State University, Logan, UT, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+A%22">Thomas A</searchLink>; College of Agriculture and Applied Sciences, Utah State University, Logan, UT, USA.<br /><searchLink fieldCode="AU" term="%22Beisel+CL%22">Beisel CL</searchLink>; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Centre for Infection Research (HZI), Würzburg, Germany.; Medical Faculty, University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Jackson+RN%22">Jackson RN</searchLink>; Department of Chemistry and Biochemistry, Utah State University, Logan, UT, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 May 30. <i>Date of Electronic Publication: </i>2026 May 30.
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        Value: 10.1101/2025.01.05.631166
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