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Human neurons stimulated with IFNγ present HLA class I-restricted autoantigens to cytotoxic CD8+ T cells.

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Title: Human neurons stimulated with IFNγ present HLA class I-restricted autoantigens to cytotoxic CD8+ T cells.
Authors: Clarkson BD; Translational Neuroimmunology Laboratory, Mayo Clinic, Rochester, Minnesota, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.; Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, Rochester, Minnesota, USA., Pucci S; Translational Neuroimmunology Laboratory, Mayo Clinic, Rochester, Minnesota, USA., Shrestha RB; Translational Neuroimmunology Laboratory, Mayo Clinic, Rochester, Minnesota, USA., Mangalaparthi KK; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Raja R; Department of Immunology, Mayo Clinic, Phoenix, Arizona, USA., Curtis M; Department of Immunology, Mayo Clinic, Phoenix, Arizona, USA.; Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Phoenix, Arizona, USA., Pandey A; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.; Manipal Academy of Higher Education, Manipal, Karnataka, India.; Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA., Howe CL; Translational Neuroimmunology Laboratory, Mayo Clinic, Rochester, Minnesota, USA.; Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, Rochester, Minnesota, USA.; Division of Experimental Neurology, Mayo Clinic, Rochester, Minnesota, USA.; Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.; Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 May 26. Date of Electronic Publication: 2026 May 26.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Human neurons stimulated with IFNγ present HLA class I-restricted autoantigens to cytotoxic CD8<superscript>+</superscript> T cells.
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  Data: <searchLink fieldCode="AU" term="%22Clarkson+BD%22">Clarkson BD</searchLink>; Translational Neuroimmunology Laboratory, Mayo Clinic, Rochester, Minnesota, USA.; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.; Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Pucci+S%22">Pucci S</searchLink>; Translational Neuroimmunology Laboratory, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Shrestha+RB%22">Shrestha RB</searchLink>; Translational Neuroimmunology Laboratory, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Mangalaparthi+KK%22">Mangalaparthi KK</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Raja+R%22">Raja R</searchLink>; Department of Immunology, Mayo Clinic, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Curtis+M%22">Curtis M</searchLink>; Department of Immunology, Mayo Clinic, Phoenix, Arizona, USA.; Mayo Clinic Comprehensive Cancer Center, Mayo Clinic, Phoenix, Arizona, USA.<br /><searchLink fieldCode="AU" term="%22Pandey+A%22">Pandey A</searchLink>; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.; Manipal Academy of Higher Education, Manipal, Karnataka, India.; Center for Individualized Medicine, Mayo Clinic, Rochester, MN, USA.<br /><searchLink fieldCode="AU" term="%22Howe+CL%22">Howe CL</searchLink>; Translational Neuroimmunology Laboratory, Mayo Clinic, Rochester, Minnesota, USA.; Center for Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic, Rochester, Minnesota, USA.; Division of Experimental Neurology, Mayo Clinic, Rochester, Minnesota, USA.; Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.; Department of Immunology, Mayo Clinic, Rochester, Minnesota, USA.
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  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 May 26. <i>Date of Electronic Publication: </i>2026 May 26.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.64898/2026.05.22.727243
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      – Code: eng
        Text: English
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      – TitleFull: Human neurons stimulated with IFNγ present HLA class I-restricted autoantigens to cytotoxic CD8+ T cells.
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            – D: 26
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              Text: 2026 May 26
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              Y: 2026
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