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Machine Learning-Guided Survival Prediction and Treatment Sequencing in Advanced Soft Tissue Sarcoma Beyond Second-Line Therapy: A Retrospective Cohort Study.

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Title: Machine Learning-Guided Survival Prediction and Treatment Sequencing in Advanced Soft Tissue Sarcoma Beyond Second-Line Therapy: A Retrospective Cohort Study.
Authors: Hoberger M; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany., Di Gioia D; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany., Zuber RL; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany., Völkl M; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany., Güler SE; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany., Jurinovic V; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.; Institute for Medical Information Processing, Biometry, and Epidemiology, University Hospital, LMU Munich, Munich, Germany., Albertsmeier M; Department of General, Visceral and Transplantation Surgery, University Hospital, LMU Munich, Munich, Germany., Klein A; Orthopaedic Oncology, Department of Orthopaedics and Trauma Surgery, University Hospital, LMU Munich, Munich, Germany., Dürr HR; Orthopaedic Oncology, Department of Orthopaedics and Trauma Surgery, University Hospital, LMU Munich, Munich, Germany., Schmidt-Hegemann NS; Department of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany., Knösel T; Institute of Pathology, LMU Munich, Munich, Germany., Kunz WG; Department of Radiology, University Hospital, LMU Munich, Munich, Germany.; Bavarian Cancer Research Center (BZKF), Munich, Germany., von Bergwelt-Baildon M; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.; Bavarian Cancer Research Center (BZKF), Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany., Lindner LH; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.; Bavarian Cancer Research Center (BZKF), Munich, Germany., Burkhard-Meier A; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.; Bavarian Cancer Research Center (BZKF), Munich, Germany., Berclaz LM; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany. Luc.Berclaz@med.uni-muenchen.de.; Bavarian Cancer Research Center (BZKF), Munich, Germany. Luc.Berclaz@med.uni-muenchen.de.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany. Luc.Berclaz@med.uni-muenchen.de.
Source: Oncology and therapy [Oncol Ther] 2026 Jun 05. Date of Electronic Publication: 2026 Jun 05.
Publication Type: Journal Article
Journal Info: Publisher: Adis Country of Publication: New Zealand NLM ID: 101677510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2366-1089 (Electronic) Linking ISSN: 23661089 NLM ISO Abbreviation: Oncol Ther
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Hoberger+M%22">Hoberger M</searchLink>; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Di+Gioia+D%22">Di Gioia D</searchLink>; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Zuber+RL%22">Zuber RL</searchLink>; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Völkl+M%22">Völkl M</searchLink>; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Güler+SE%22">Güler SE</searchLink>; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Jurinovic+V%22">Jurinovic V</searchLink>; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.; Institute for Medical Information Processing, Biometry, and Epidemiology, University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Albertsmeier+M%22">Albertsmeier M</searchLink>; Department of General, Visceral and Transplantation Surgery, University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Klein+A%22">Klein A</searchLink>; Orthopaedic Oncology, Department of Orthopaedics and Trauma Surgery, University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Dürr+HR%22">Dürr HR</searchLink>; Orthopaedic Oncology, Department of Orthopaedics and Trauma Surgery, University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidt-Hegemann+NS%22">Schmidt-Hegemann NS</searchLink>; Department of Radiation Oncology, University Hospital, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Knösel+T%22">Knösel T</searchLink>; Institute of Pathology, LMU Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kunz+WG%22">Kunz WG</searchLink>; Department of Radiology, University Hospital, LMU Munich, Munich, Germany.; Bavarian Cancer Research Center (BZKF), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22von+Bergwelt-Baildon+M%22">von Bergwelt-Baildon M</searchLink>; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.; Bavarian Cancer Research Center (BZKF), Munich, Germany.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Lindner+LH%22">Lindner LH</searchLink>; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.; Bavarian Cancer Research Center (BZKF), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Burkhard-Meier+A%22">Burkhard-Meier A</searchLink>; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany.; Bavarian Cancer Research Center (BZKF), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Berclaz+LM%22">Berclaz LM</searchLink>; Department of Medicine III, University Hospital, Ludwig-Maximilians-University (LMU) Munich, Marchioninistr. 15, 81377, Munich, Germany. Luc.Berclaz@med.uni-muenchen.de.; Bavarian Cancer Research Center (BZKF), Munich, Germany. Luc.Berclaz@med.uni-muenchen.de.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany. Luc.Berclaz@med.uni-muenchen.de.
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