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Disrupting phage liquid crystalline droplets restores antibiotic susceptibility in Pseudomonas aeruginosa biofilms.

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Title: Disrupting phage liquid crystalline droplets restores antibiotic susceptibility in Pseudomonas aeruginosa biofilms.
Authors: Tarafder AK; Structural Studies Division, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, United Kingdom., Graham M; Structural Studies Division, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, United Kingdom., Davis LK; School of Mathematics, University of Edinburgh, Edinburgh, United Kingdom.; Higgs Centre for Theoretical Physics, University of Edinburgh, Edinburgh, United Kingdom.; Department of Mathematics, University College London, London, United Kingdom., Pratt S; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America., Böhning J; Structural Studies Division, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, United Kingdom., Manivannan P; Structural Studies Division, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, United Kingdom., Wang Z; Structural Studies Division, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, United Kingdom., Clemente CM; Structural Studies Division, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, United Kingdom., Weimann A; Victor Phillip Dahdaleh Heart & Lung Research Institute, University of Cambridge, Cambridge, United Kingdom.; Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.; Cambridge Centre for AI in Medicine, University of Cambridge, Cambridge, United Kingdom., Floto RA; Victor Phillip Dahdaleh Heart & Lung Research Institute, University of Cambridge, Cambridge, United Kingdom.; Cambridge Centre for AI in Medicine, University of Cambridge, Cambridge, United Kingdom.; Cambridge Centre for Lung Infection, Royal Papworth Hospital, Cambridge, United Kingdom., Owens RJ; Division of Structural Biology, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Rosalind Franklin Institute, Harwell Science Campus, Didcot, United Kingdom., O'Toole GA; Department of Microbiology and Immunology, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, United States of America., Pearce P; Department of Mathematics, University College London, London, United Kingdom.; Institute for the Physics of Living Systems, University College London, London, United Kingdom., Bharat TAM; Structural Studies Division, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, United Kingdom.
Source: PLoS biology [PLoS Biol] 2026 Jun 05; Vol. 24 (6), pp. e3003834. Date of Electronic Publication: 2026 Jun 05 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE
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