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Changes in the metabolome after treatment with canagliflozin in patients with type 2 diabetes.

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Title: Changes in the metabolome after treatment with canagliflozin in patients with type 2 diabetes.
Authors: Coorey CP; Cardiology Discovery Group, Kolling Institute of Medical Research, St Leonards, New South Wales, Australia.; Department of Cardiology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Tang O; Cardiology Discovery Group, Kolling Institute of Medical Research, St Leonards, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia., Li M; Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, Victoria, Australia., Kim T; Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.; School of Mathematics and Statistics, The University of Sydney, Sydney, New South Wales, Australia., Vescovi J; Cardiology Discovery Group, Kolling Institute of Medical Research, St Leonards, New South Wales, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia., Vernon ST; Cardiology Discovery Group, Kolling Institute of Medical Research, St Leonards, New South Wales, Australia.; Department of Cardiology, Royal North Shore Hospital, St Leonards, New South Wales, Australia., Neal B; The George Institute for Global Health, Sydney, New South Wales, Australia.; Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia., Arnott C; The George Institute for Global Health, Sydney, New South Wales, Australia.; Department of Cardiology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia., Ferrannini E; CNR (National Research Council) Institute of Clinical Physiology, Pisa, Italy., Burrell LM; Department of Medicine, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Cardiology, Austin Health, Heidelberg, Victoria, Australia., Mahaffey KW; Stanford Center for Clinical Research, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Grieve SM; Imaging and Phenotyping Laboratory, Charles Perkins Centre, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; Department of Radiology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia., Yang JYH; Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.; School of Mathematics and Statistics, The University of Sydney, Sydney, New South Wales, Australia., O'Sullivan JF; Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; Centre for Heart Failure and Diseases of the Aorta, The Baird Institute, Sydney, New South Wales, Australia., Figtree GA; Cardiology Discovery Group, Kolling Institute of Medical Research, St Leonards, New South Wales, Australia gemma.figtree@sydney.edu.au.; Department of Cardiology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
Source: Heart (British Cardiac Society) [Heart] 2026 Jun 05. Date of Electronic Publication: 2026 Jun 05.
Publication Type: Journal Article
Journal Info: Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 9602087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-201X (Electronic) Linking ISSN: 13556037 NLM ISO Abbreviation: Heart Subsets: MEDLINE
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  Data: Changes in the metabolome after treatment with canagliflozin in patients with type 2 diabetes.
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  Data: <searchLink fieldCode="AU" term="%22Coorey+CP%22">Coorey CP</searchLink>; Cardiology Discovery Group, Kolling Institute of Medical Research, St Leonards, New South Wales, Australia.; Department of Cardiology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Tang+O%22">Tang O</searchLink>; Cardiology Discovery Group, Kolling Institute of Medical Research, St Leonards, New South Wales, Australia.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Bioinformatics Division, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Kim+T%22">Kim T</searchLink>; Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.; School of Mathematics and Statistics, The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Vescovi+J%22">Vescovi J</searchLink>; Cardiology Discovery Group, Kolling Institute of Medical Research, St Leonards, New South Wales, Australia.; Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Vernon+ST%22">Vernon ST</searchLink>; Cardiology Discovery Group, Kolling Institute of Medical Research, St Leonards, New South Wales, Australia.; Department of Cardiology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Neal+B%22">Neal B</searchLink>; The George Institute for Global Health, Sydney, New South Wales, Australia.; Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Arnott+C%22">Arnott C</searchLink>; The George Institute for Global Health, Sydney, New South Wales, Australia.; Department of Cardiology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Ferrannini+E%22">Ferrannini E</searchLink>; CNR (National Research Council) Institute of Clinical Physiology, Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Burrell+LM%22">Burrell LM</searchLink>; Department of Medicine, The University of Melbourne, Melbourne, Victoria, Australia.; Department of Cardiology, Austin Health, Heidelberg, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Mahaffey+KW%22">Mahaffey KW</searchLink>; Stanford Center for Clinical Research, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.<br /><searchLink fieldCode="AU" term="%22Grieve+SM%22">Grieve SM</searchLink>; Imaging and Phenotyping Laboratory, Charles Perkins Centre, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; Department of Radiology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Yang+JYH%22">Yang JYH</searchLink>; Charles Perkins Centre, The University of Sydney, Sydney, New South Wales, Australia.; School of Mathematics and Statistics, The University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22O'Sullivan+JF%22">O'Sullivan JF</searchLink>; Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.; School of Medical Sciences, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.; Centre for Heart Failure and Diseases of the Aorta, The Baird Institute, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Figtree+GA%22">Figtree GA</searchLink>; Cardiology Discovery Group, Kolling Institute of Medical Research, St Leonards, New South Wales, Australia gemma.figtree@sydney.edu.au.; Department of Cardiology, Royal North Shore Hospital, St Leonards, New South Wales, Australia.
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        Value: 10.1136/heartjnl-2025-327466
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        Text: English
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      – TitleFull: Changes in the metabolome after treatment with canagliflozin in patients with type 2 diabetes.
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              Text: 2026 Jun 05
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