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Aging of the adaptive immune system affects the gut microbiome and systemic levels of vitamin B6.

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Title: Aging of the adaptive immune system affects the gut microbiome and systemic levels of vitamin B6.
Authors: Stahl S; Institute of Molecular Medicine, Ulm University, Ulm, Baden-Württemberg, 89081, Germany., Widmaier H; Department of Internal Medicine I, University Hospital of Ulm, Ulm, Baden-Württemberg, 89081, Germany., Sakk V; Institute of Molecular Medicine, Ulm University, Ulm, Baden-Württemberg, 89081, Germany., Nalapareddy K; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA., Kissmann AK; Institute of Pharmaceutical Biotechnology, Ulm University, Ulm, Baden-Württemberg, 89081, Germany., Rosenau F; Institute of Pharmaceutical Biotechnology, Ulm University, Ulm, Baden-Württemberg, 89081, Germany., Mulaw MA; Unit for Single-Cell Genomics, Ulm University, Ulm, Baden-Württemberg, 89081, Germany., Haslam DB; Microbial Genomics and Metagenomics Laboratory, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA., Geiger H; Institute of Molecular Medicine, Ulm University, Ulm, Baden-Württemberg, 89081, Germany. hartmut.geiger@uni-ulm.de.
Source: Microbiome [Microbiome] 2026 Jun 05; Vol. 14 (1). Date of Electronic Publication: 2026 Jun 05.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101615147 Publication Model: Electronic Cited Medium: Internet ISSN: 2049-2618 (Electronic) Linking ISSN: 20492618 NLM ISO Abbreviation: Microbiome Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Stahl+S%22">Stahl S</searchLink>; Institute of Molecular Medicine, Ulm University, Ulm, Baden-Württemberg, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Widmaier+H%22">Widmaier H</searchLink>; Department of Internal Medicine I, University Hospital of Ulm, Ulm, Baden-Württemberg, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Sakk+V%22">Sakk V</searchLink>; Institute of Molecular Medicine, Ulm University, Ulm, Baden-Württemberg, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Nalapareddy+K%22">Nalapareddy K</searchLink>; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA.<br /><searchLink fieldCode="AU" term="%22Kissmann+AK%22">Kissmann AK</searchLink>; Institute of Pharmaceutical Biotechnology, Ulm University, Ulm, Baden-Württemberg, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Rosenau+F%22">Rosenau F</searchLink>; Institute of Pharmaceutical Biotechnology, Ulm University, Ulm, Baden-Württemberg, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Mulaw+MA%22">Mulaw MA</searchLink>; Unit for Single-Cell Genomics, Ulm University, Ulm, Baden-Württemberg, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Haslam+DB%22">Haslam DB</searchLink>; Microbial Genomics and Metagenomics Laboratory, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, 45229, USA.<br /><searchLink fieldCode="AU" term="%22Geiger+H%22">Geiger H</searchLink>; Institute of Molecular Medicine, Ulm University, Ulm, Baden-Württemberg, 89081, Germany. hartmut.geiger@uni-ulm.de.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101615147 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2049-2618 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220492618%22">20492618 </searchLink><i>NLM ISO Abbreviation: </i>Microbiome <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s40168-026-02428-3
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              Text: 2026 Jun 05
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