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Low folate status and related polymorphisms are associated with lower sperm quality in healthy males: The Lifestyle and Environmental Determinants of Seminogram and Other Male Fertility-Related Parameters (Led-Fertyl) cross-sectional study.

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Title: Low folate status and related polymorphisms are associated with lower sperm quality in healthy males: The Lifestyle and Environmental Determinants of Seminogram and Other Male Fertility-Related Parameters (Led-Fertyl) cross-sectional study.
Authors: Eigbefoh-Addeh A; Unit of Preventive Medicine and Biostatistics, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain; Institut de Recerca Biomèdica Catalunya Sud (IRBCatSud), Reus, Spain; Research Group, Alimentació, Nutrició, Desenvolupament i Salut Mental (ANUT-DSM)., Salas-Huetos A; Unit of Preventive Medicine and Biostatistics, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain; Institut de Recerca Biomèdica Catalunya Sud (IRBCatSud), Reus, Spain; Research Group, Alimentació, Nutrició, Desenvolupament i Salut Mental (ANUT-DSM); Institute of Health Carlos III, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Madrid, Spain; Department of Nutrition, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, United States. Electronic address: albert.salas@urv.cat., Ramos-Rodríguez C; Unit of Preventive Medicine and Biostatistics, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain; Institut de Recerca Biomèdica Catalunya Sud (IRBCatSud), Reus, Spain; Research Group, Alimentació, Nutrició, Desenvolupament i Salut Mental (ANUT-DSM)., Santos-Calderón LA; Unit of Preventive Medicine and Biostatistics, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain; Institut de Recerca Biomèdica Catalunya Sud (IRBCatSud), Reus, Spain; Research Group, Alimentació, Nutrició, Desenvolupament i Salut Mental (ANUT-DSM)., Agarwal R; Institut de Recerca Biomèdica Catalunya Sud (IRBCatSud), Reus, Spain; Research Group, Alimentació, Nutrició, Desenvolupament i Salut Mental (ANUT-DSM); Institute of Health Carlos III, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Madrid, Spain; Department of Biochemistry and Biotechnology, Unit of Human Nutrition, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain., Salas-Salvadó J; Institut de Recerca Biomèdica Catalunya Sud (IRBCatSud), Reus, Spain; Research Group, Alimentació, Nutrició, Desenvolupament i Salut Mental (ANUT-DSM); Institute of Health Carlos III, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Madrid, Spain; Department of Biochemistry and Biotechnology, Unit of Human Nutrition, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain., Babio N; Institut de Recerca Biomèdica Catalunya Sud (IRBCatSud), Reus, Spain; Research Group, Alimentació, Nutrició, Desenvolupament i Salut Mental (ANUT-DSM); Institute of Health Carlos III, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Madrid, Spain; Department of Biochemistry and Biotechnology, Unit of Human Nutrition, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain., McCann A; Bevital A/S, Bergen, Norway., Ueland PM; Bevital A/S, Bergen, Norway., Murphy MM; Unit of Preventive Medicine and Biostatistics, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain; Institut de Recerca Biomèdica Catalunya Sud (IRBCatSud), Reus, Spain; Research Group, Alimentació, Nutrició, Desenvolupament i Salut Mental (ANUT-DSM); Institute of Health Carlos III, Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Madrid, Spain.
Source: The American journal of clinical nutrition [Am J Clin Nutr] 2026 Jun 06, pp. 101385. Date of Electronic Publication: 2026 Jun 06.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0376027 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-3207 (Electronic) Linking ISSN: 00029165 NLM ISO Abbreviation: Am J Clin Nutr Subsets: MEDLINE
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  Data: Low folate status and related polymorphisms are associated with lower sperm quality in healthy males: The Lifestyle and Environmental Determinants of Seminogram and Other Male Fertility-Related Parameters (Led-Fertyl) cross-sectional study.
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