The Legionella effector RidL binds the large fission GTPase Drp1 to promote mitochondrial fragmentation.

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Title: The Legionella effector RidL binds the large fission GTPase Drp1 to promote mitochondrial fragmentation.
Authors: Katic A; Institute of Medical Microbiology, University of Zürich, Zürich, Switzerland., Vittori ET; Institute of Medical Microbiology, University of Zürich, Zürich, Switzerland., Halter S; Institute of Medical Microbiology, University of Zürich, Zürich, Switzerland., Steiner K; Institute of Medical Microbiology, University of Zürich, Zürich, Switzerland.; Institute of Medical Virology, University of Zürich, Zürich, Switzerland., Swart AL; Institute of Medical Microbiology, University of Zürich, Zürich, Switzerland.; Biozentrum, University of Basel, Basel, Switzerland., Radiom M; Department of Health Sciences and Technology, ETH Zürich, Zürich, Switzerland., García-Rodríguez FJ; Institut Pasteur, Université Paris Cité, CNRS UMR 6047, Paris, France., Jäggi T; Institute of Medical Microbiology, University of Zürich, Zürich, Switzerland., Li X; Paul Scherrer Institute, Villigen, Switzerland., Mears JA; Case Western Reserve University School of Medicine, Cleveland, OH, USA., Buchrieser C; Institut Pasteur, Université Paris Cité, CNRS UMR 6047, Paris, France., Escoll P; Institut Pasteur, Université Paris Cité, CNRS UMR 6047, Paris, France., Panse VG; Institute of Medical Microbiology, University of Zürich, Zürich, Switzerland.; Faculty of Science, University of Zürich, Zürich, Switzerland., Hilbi H; Institute of Medical Microbiology, University of Zürich, Zürich, Switzerland. hilbi@imm.uzh.ch.
Source: EMBO reports [EMBO Rep] 2026 Jul; Vol. 27 (13), pp. 3759-3787. Date of Electronic Publication: 2026 Jun 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1469-3178
DOI:10.1038/s44319-026-00823-3