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Early microglial response to amyloid plaques drives sleep loss in Alzheimer's disease.

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Title: Early microglial response to amyloid plaques drives sleep loss in Alzheimer's disease.
Authors: Constantino NJ; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA.; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, USA., Irmen RE; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA., Lanning MJ; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA., Turner SM; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA., Ashley CC; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA., Carroll CM; Department of Psychiatry, Alzheimer's Disease Research Center, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA., Neary EM; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA., Rubinow D; LifeCanvas Technologies, Cambridge, Massachusetts, USA., Snipes JA; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA., Macauley SL; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA.; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, USA.; Sanders Brown Center of Aging, University of Kentucky, Lexington, Kentucky, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2026 Jun; Vol. 22 (6), pp. e71579.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Early microglial response to amyloid plaques drives sleep loss in Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Constantino+NJ%22">Constantino NJ</searchLink>; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA.; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Irmen+RE%22">Irmen RE</searchLink>; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Lanning+MJ%22">Lanning MJ</searchLink>; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Turner+SM%22">Turner SM</searchLink>; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Ashley+CC%22">Ashley CC</searchLink>; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Carroll+CM%22">Carroll CM</searchLink>; Department of Psychiatry, Alzheimer's Disease Research Center, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Neary+EM%22">Neary EM</searchLink>; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Rubinow+D%22">Rubinow D</searchLink>; LifeCanvas Technologies, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Snipes+JA%22">Snipes JA</searchLink>; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA.<br /><searchLink fieldCode="AU" term="%22Macauley+SL%22">Macauley SL</searchLink>; Department of Physiology, University of Kentucky, Lexington, Kentucky, USA.; Department of Neuroscience, University of Kentucky, Lexington, Kentucky, USA.; Sanders Brown Center of Aging, University of Kentucky, Lexington, Kentucky, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Ltd%22">John Wiley & Sons, Ltd </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101231978 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5279 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215525260%22">15525260 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement <i>Subsets: </i>MEDLINE
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        Value: 10.1002/alz.71579
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        Text: English
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      – TitleFull: Early microglial response to amyloid plaques drives sleep loss in Alzheimer's disease.
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            – D: 01
              M: 06
              Text: 2026 Jun
              Type: published
              Y: 2026
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