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Integrative Multiomics Analysis Identifies a Novel Gene Signature That Predicts Chemotherapy Resistance and Poor Survival in Osteosarcoma.

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Title: Integrative Multiomics Analysis Identifies a Novel Gene Signature That Predicts Chemotherapy Resistance and Poor Survival in Osteosarcoma.
Authors: Yang X; Department of Pathology, Medical School of Nantong University, Nantong, China, ntu.edu.cn.; Department of Orthopedic Oncology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, sjtu.edu.cn., Lu X; Affiliated Qidong Hospital of Nantong University, Qidong People's Hospital, Qidong Liver Cancer Institute, Qidong, China., Gao Z; Department of Joint Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China, tongji.edu.cn., Lv W; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn., Shen S; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn., Liu S; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn., Li Z; Department of Pathology, Medical School of Nantong University, Nantong, China, ntu.edu.cn., Liu R; Department of Pathology, Medical School of Nantong University, Nantong, China, ntu.edu.cn., Wang X; Department of Pathology, Medical School of Nantong University, Nantong, China, ntu.edu.cn., Shen Y; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn., Yu D; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn., Jin X; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn., Wang H; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn., Tang J; Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China, sjtu.edu.cn., Tang Z; Department of Pathology, Medical School of Nantong University, Nantong, China, ntu.edu.cn.
Source: Human mutation [Hum Mutat] 2026 May 30; Vol. 2026, pp. 8885469. Date of Electronic Publication: 2026 May 30 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 9215429 Publication Model: eCollection Cited Medium: Internet ISSN: 1098-1004 (Electronic) Linking ISSN: 10597794 NLM ISO Abbreviation: Hum Mutat Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Integrative Multiomics Analysis Identifies a Novel Gene Signature That Predicts Chemotherapy Resistance and Poor Survival in Osteosarcoma.
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  Data: <searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Department of Pathology, Medical School of Nantong University, Nantong, China, ntu.edu.cn.; Department of Orthopedic Oncology, Shanghai General Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China, sjtu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Lu+X%22">Lu X</searchLink>; Affiliated Qidong Hospital of Nantong University, Qidong People's Hospital, Qidong Liver Cancer Institute, Qidong, China.<br /><searchLink fieldCode="AU" term="%22Gao+Z%22">Gao Z</searchLink>; Department of Joint Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China, tongji.edu.cn.<br /><searchLink fieldCode="AU" term="%22Lv+W%22">Lv W</searchLink>; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.<br /><searchLink fieldCode="AU" term="%22Shen+S%22">Shen S</searchLink>; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Department of Pathology, Medical School of Nantong University, Nantong, China, ntu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+R%22">Liu R</searchLink>; Department of Pathology, Medical School of Nantong University, Nantong, China, ntu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Department of Pathology, Medical School of Nantong University, Nantong, China, ntu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Shen+Y%22">Shen Y</searchLink>; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.<br /><searchLink fieldCode="AU" term="%22Yu+D%22">Yu D</searchLink>; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.<br /><searchLink fieldCode="AU" term="%22Jin+X%22">Jin X</searchLink>; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Department of Medical Oncology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China, tongji.edu.cn.<br /><searchLink fieldCode="AU" term="%22Tang+J%22">Tang J</searchLink>; Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China, sjtu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Tang+Z%22">Tang Z</searchLink>; Department of Pathology, Medical School of Nantong University, Nantong, China, ntu.edu.cn.
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