Green-synthesized ZnO-MnO nanocomposite as a potent antimicrobial and antibiofilm agent: protein leakage mechanism and synergistic interaction with cefotaxime.

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Title: Green-synthesized ZnO-MnO nanocomposite as a potent antimicrobial and antibiofilm agent: protein leakage mechanism and synergistic interaction with cefotaxime.
Authors: Abdulrahman MS; Department of Microbiology and Immunology, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.; Department of Microbiology and Immunology, Faculty of Pharmacy, Menoufia National University, Menoufia, Egypt., Ibrahim NA; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia., Hashem AH; Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Cairo, Egypt., Saied E; Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Cairo, Egypt., Elkady FM; Department of Microbiology and Immunology, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt., Abdel Tawab A; Department of Microbiology and Immunology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt., Badr BM; Department of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan.; Department of Medical Microbiology and Immunology, Faculty of Medicine, Al-Azhar University (Assiut Branch), Assiut, Egypt., Selim S; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Saudi Arabia., Alzahrani AJ; Department of Biological Sciences, Faculty of Science, University of Jeddah, Jeddah, Saudi Arabia., Alhassan HH; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Saudi Arabia., Basher NS; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia., Alsalamah SA; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia., Nasr FA; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia., Aufy M; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, Vienna, Austria.
Source: Frontiers in microbiology [Front Microbiol] 2026 May 22; Vol. 17, pp. 1851865. Date of Electronic Publication: 2026 May 22 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101548977 Publication Model: eCollection Cited Medium: Print ISSN: 1664-302X (Print) Linking ISSN: 1664302X NLM ISO Abbreviation: Front Microbiol Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Abdulrahman+MS%22">Abdulrahman MS</searchLink>; Department of Microbiology and Immunology, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.; Department of Microbiology and Immunology, Faculty of Pharmacy, Menoufia National University, Menoufia, Egypt.<br /><searchLink fieldCode="AU" term="%22Ibrahim+NA%22">Ibrahim NA</searchLink>; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Hashem+AH%22">Hashem AH</searchLink>; Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Saied+E%22">Saied E</searchLink>; Department of Botany and Microbiology, Faculty of Science, Al-Azhar University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Elkady+FM%22">Elkady FM</searchLink>; Department of Microbiology and Immunology, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Abdel+Tawab+A%22">Abdel Tawab A</searchLink>; Department of Microbiology and Immunology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Badr+BM%22">Badr BM</searchLink>; Department of Basic Medical and Dental Sciences, Faculty of Dentistry, Zarqa University, Zarqa, Jordan.; Department of Medical Microbiology and Immunology, Faculty of Medicine, Al-Azhar University (Assiut Branch), Assiut, Egypt.<br /><searchLink fieldCode="AU" term="%22Selim+S%22">Selim S</searchLink>; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alzahrani+AJ%22">Alzahrani AJ</searchLink>; Department of Biological Sciences, Faculty of Science, University of Jeddah, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alhassan+HH%22">Alhassan HH</searchLink>; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Basher+NS%22">Basher NS</searchLink>; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alsalamah+SA%22">Alsalamah SA</searchLink>; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Nasr+FA%22">Nasr FA</searchLink>; Department of Biology, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Aufy+M%22">Aufy M</searchLink>; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, Vienna, Austria.
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