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Scaling human liver microphysiological systems: implementing a higher-throughput liver acinus microphysiological system platform.

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Title: Scaling human liver microphysiological systems: implementing a higher-throughput liver acinus microphysiological system platform.
Authors: Gavlock DC; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States., Castiglione MW; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States., Wang A; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States., Varmazyad M; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.; Department of Computational and System Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA, United States., Vernetti LA; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.; Department of Computational and System Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA, United States., Schurdak ME; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.; Department of Computational and System Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA, United States., Taylor DL; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.; Department of Computational and System Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA, United States., Brown JA; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.; Department of Computational and System Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA, United States., Miedel MT; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA, United States.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, United States.
Source: Experimental biology and medicine (Maywood, N.J.) [Exp Biol Med (Maywood)] 2026 May 22; Vol. 251, pp. 11038. Date of Electronic Publication: 2026 May 22 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 100973463 Publication Model: eCollection Cited Medium: Internet ISSN: 1535-3699 (Electronic) Linking ISSN: 15353699 NLM ISO Abbreviation: Exp Biol Med (Maywood) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Scaling human liver microphysiological systems: implementing a higher-throughput liver acinus microphysiological system platform.
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  Data: <searchLink fieldCode="AU" term="%22Gavlock+DC%22">Gavlock DC</searchLink>; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Castiglione+MW%22">Castiglione MW</searchLink>; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Wang+A%22">Wang A</searchLink>; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Varmazyad+M%22">Varmazyad M</searchLink>; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.; Department of Computational and System Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Vernetti+LA%22">Vernetti LA</searchLink>; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.; Department of Computational and System Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Schurdak+ME%22">Schurdak ME</searchLink>; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.; Department of Computational and System Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Taylor+DL%22">Taylor DL</searchLink>; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.; Department of Computational and System Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Brown+JA%22">Brown JA</searchLink>; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.; Department of Computational and System Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States.; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA, United States.<br /><searchLink fieldCode="AU" term="%22Miedel+MT%22">Miedel MT</searchLink>; Organ Pathobiology and Therapeutic Institute, University of Pittsburgh, Pittsburgh, PA, United States.; Pittsburgh Liver Research Center, University of Pittsburgh, Pittsburgh, PA, United States.; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, PA, United States.
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  Data: <searchLink fieldCode="JN" term="%22100973463%22">Experimental biology and medicine (Maywood, N.J.)</searchLink> [Exp Biol Med (Maywood)] 2026 May 22; Vol. 251, pp. 11038. <i>Date of Electronic Publication: </i>2026 May 22 (<i>Print Publication: </i>2026).
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              Text: 2026 May 22
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