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Extracellular vesicle microRNA signature as a highly accurate diagnostic biomarker for human brucellosis.

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Title: Extracellular vesicle microRNA signature as a highly accurate diagnostic biomarker for human brucellosis.
Authors: Wu J; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China., Zhang L; School of Pharmaceutical Sciences, Guangzhou Kingmed Center for Clinical Laboratory, Guangzhou, China., He Y; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China., Deng H; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China., Cao F; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China., Liu Y; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China., Peng P; Medical Department, Xizang Minzu University, Xianyang, China., Su J; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China., Wei J; The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China., Lin X; The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China., Yi Q; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China., Zhan L; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China., Yin X; Department of Laboratory Medicine, Red Cross Hospital, Jinan University, Guangzhou, China., Yang Y; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China., Liao Y; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China., Wang L; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China.
Source: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2026 May 22; Vol. 16, pp. 1806232. Date of Electronic Publication: 2026 May 22 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE
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  Data: Extracellular vesicle microRNA signature as a highly accurate diagnostic biomarker for human brucellosis.
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  Data: <searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; School of Pharmaceutical Sciences, Guangzhou Kingmed Center for Clinical Laboratory, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22He+Y%22">He Y</searchLink>; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Deng+H%22">Deng H</searchLink>; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Cao+F%22">Cao F</searchLink>; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; 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The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lin+X%22">Lin X</searchLink>; The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yi+Q%22">Yi Q</searchLink>; School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhan+L%22">Zhan L</searchLink>; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yin+X%22">Yin X</searchLink>; Department of Laboratory Medicine, Red Cross Hospital, Jinan University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Liao+Y%22">Liao Y</searchLink>; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; KingMed School of Laboratory Medicine, Guangzhou Medical University, Guangzhou, China.; Institute of Medical Laboratory Big Data & Economics, Guangzhou Medical University, Guangzhou, China.; Engineering Technology Research Center of Intelligent Diagnosis for Infectious Diseases in Guangdong Province, Guangzhou, China.; Guangzhou Key Laboratory for Clinical Rapid Diagnosis and Early Warning of Infectious Diseases, Guangzhou, China.; Medical Department, Guangdong Provincial Engineering Research Center for Early Warning and Diagnosis of Respiratory Infectious Diseases, Guangzhou, China.
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  Data: <searchLink fieldCode="JN" term="%22101585359%22">Frontiers in cellular and infection microbiology</searchLink> [Front Cell Infect Microbiol] 2026 May 22; Vol. 16, pp. 1806232. <i>Date of Electronic Publication: </i>2026 May 22 (<i>Print Publication: </i>2026).
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