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Afatinib Versus Osimertinib as First-Line Treatment for Advanced EGFR-Mutant Non-Small-Cell Lung Cancer: A 3-Year Follow-Up Overall Survival Analysis.

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Title: Afatinib Versus Osimertinib as First-Line Treatment for Advanced EGFR-Mutant Non-Small-Cell Lung Cancer: A 3-Year Follow-Up Overall Survival Analysis.
Authors: Huang YH; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; Lung Cancer Comprehensive Care and Research Center, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sect. 2, Linong St., Taipei, 112, Taiwan., Hsu KH; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; Lung Cancer Comprehensive Care and Research Center, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan., Tseng JS; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; Lung Cancer Comprehensive Care and Research Center, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sect. 2, Linong St., Taipei, 112, Taiwan.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung, 402, Taiwan.; Institute of Biomedical Sciences, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung, 402, Taiwan., Lee PH; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; Lung Cancer Comprehensive Care and Research Center, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sect. 2, Linong St., Taipei, 112, Taiwan.; Doctoral Program in Translational Medicine, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung, 402, Taiwan.; Rong Hsing Translational Medicine Research Center, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung, 402, Taiwan., Lin IH; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan., Peng MH; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan., Yang TY; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan. jonyin@gmail.com.; Lung Cancer Comprehensive Care and Research Center, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan. jonyin@gmail.com.; Doctoral Program in Translational Medicine, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung, 402, Taiwan. jonyin@gmail.com.; Rong Hsing Translational Medicine Research Center, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung, 402, Taiwan. jonyin@gmail.com.
Source: Targeted oncology [Target Oncol] 2026 Jun 08. Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag France Country of Publication: France NLM ID: 101270595 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1776-260X (Electronic) Linking ISSN: 17762596 NLM ISO Abbreviation: Target Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Afatinib Versus Osimertinib as First-Line Treatment for Advanced EGFR-Mutant Non-Small-Cell Lung Cancer: A 3-Year Follow-Up Overall Survival Analysis.
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  Data: <searchLink fieldCode="AU" term="%22Huang+YH%22">Huang YH</searchLink>; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; Lung Cancer Comprehensive Care and Research Center, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sect. 2, Linong St., Taipei, 112, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsu+KH%22">Hsu KH</searchLink>; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; Lung Cancer Comprehensive Care and Research Center, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tseng+JS%22">Tseng JS</searchLink>; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; Lung Cancer Comprehensive Care and Research Center, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sect. 2, Linong St., Taipei, 112, Taiwan.; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung, 402, Taiwan.; Institute of Biomedical Sciences, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung, 402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lee+PH%22">Lee PH</searchLink>; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; Lung Cancer Comprehensive Care and Research Center, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.; School of Medicine, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sect. 2, Linong St., Taipei, 112, Taiwan.; Doctoral Program in Translational Medicine, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung, 402, Taiwan.; Rong Hsing Translational Medicine Research Center, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung, 402, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+IH%22">Lin IH</searchLink>; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.<br /><searchLink fieldCode="AU" term="%22Peng+MH%22">Peng MH</searchLink>; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+TY%22">Yang TY</searchLink>; Department of Chest Medicine, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan. jonyin@gmail.com.; Lung Cancer Comprehensive Care and Research Center, Taichung Veterans General Hospital, No. 1650, Sect. 4, Taiwan Boulevard, Taichung, 407, Taiwan. jonyin@gmail.com.; Doctoral Program in Translational Medicine, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung, 402, Taiwan. jonyin@gmail.com.; Rong Hsing Translational Medicine Research Center, National Chung Hsing University, No. 145, Xingda Rd., South Dist., Taichung, 402, Taiwan. jonyin@gmail.com.
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      – Type: doi
        Value: 10.1007/s11523-026-01224-1
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      – Code: eng
        Text: English
    Titles:
      – TitleFull: Afatinib Versus Osimertinib as First-Line Treatment for Advanced EGFR-Mutant Non-Small-Cell Lung Cancer: A 3-Year Follow-Up Overall Survival Analysis.
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          Name:
            NameFull: Huang YH
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            NameFull: Hsu KH
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            NameFull: Tseng JS
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            NameFull: Lee PH
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            NameFull: Lin IH
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            NameFull: Peng MH
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          Dates:
            – D: 08
              M: 06
              Text: 2026 Jun 08
              Type: published
              Y: 2026
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            – TitleFull: Targeted oncology
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