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Temporal transcriptomic profiling identifies core regulators in cytokine-induced gut barrier disruption in differentiated Caco-2 cells.

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Bibliographic Details
Title: Temporal transcriptomic profiling identifies core regulators in cytokine-induced gut barrier disruption in differentiated Caco-2 cells.
Authors: Yoon HS; Inflammation Therapeutic Area, Amgen Research, South San Francisco, CA, 94080, USA.; Amgen R&D Postdoctoral Fellows Program, South San Francisco, CA, 94080, USA., Ma S; Discovery Sciences, Advanced Technologies, & AI, Amgen Research, South San Francisco, CA, 94080, USA., Kanke M; Discovery Sciences, Advanced Technologies, & AI, Amgen Research, South San Francisco, CA, 94080, USA., Wu WJ; Inflammation Therapeutic Area, Amgen Research, South San Francisco, CA, 94080, USA., Hoang U; Discovery Sciences, Advanced Technologies, & AI, Amgen Research, South San Francisco, CA, 94080, USA., Tan JA; Discovery Sciences, Advanced Technologies, & AI, Amgen Research, South San Francisco, CA, 94080, USA., Wilks A; Translational Safety & Risk Sciences, Amgen Research, South San Francisco, CA, 94080, USA., Patel P; Translational Safety & Risk Sciences, Amgen Research, South San Francisco, CA, 94080, USA., Chandra S; Translational Safety & Risk Sciences, Amgen Research, South San Francisco, CA, 94080, USA., Luo X; Discovery Sciences, Advanced Technologies, & AI, Amgen Research, South San Francisco, CA, 94080, USA., Lu D; Discovery Sciences, Advanced Technologies, & AI, Amgen Research, South San Francisco, CA, 94080, USA., Martin S; Discovery Sciences, Advanced Technologies, & AI, Amgen Research, South San Francisco, CA, 94080, USA., Wilson M; Inflammation Therapeutic Area, Amgen Research, South San Francisco, CA, 94080, USA., Van Lookeren Campagne M; Inflammation Therapeutic Area, Amgen Research, South San Francisco, CA, 94080, USA., Li CM; Discovery Sciences, Advanced Technologies, & AI, Amgen Research, South San Francisco, CA, 94080, USA., Kao CY; Inflammation Therapeutic Area, Amgen Research, South San Francisco, CA, 94080, USA. ckao01@amgen.com.
Source: Inflammation research : official journal of the European Histamine Research Society ... [et al.] [Inflamm Res] 2026 Jun 08; Vol. 75 (1). Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9508160 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-908X (Electronic) Linking ISSN: 10233830 NLM ISO Abbreviation: Inflamm Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1420-908X
DOI:10.1007/s00011-026-02288-5