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An MRI-based radiomics model for precision subtyping of hereditary spastic paraplegia: discriminating SPG4 from SPG5.

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Title: An MRI-based radiomics model for precision subtyping of hereditary spastic paraplegia: discriminating SPG4 from SPG5.
Authors: Huang Z; School of medical imaging, Fujian Medical University, Fuzhou, China.; Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China., Zhang F; Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.; Department of Radiology, Fujian Key Laboratory of Precision Medicine for Cancer, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Department of Radiology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China., Yuan L; School of medical imaging, Fujian Medical University, Fuzhou, China.; Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China., Wan Y; School of medical imaging, Fujian Medical University, Fuzhou, China.; Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China., Yan X; Department of Neurology and Institute of Neurology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.; Department of Neurology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China., Lin X; Department of Neurology and Institute of Neurology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China. linxiang1988@fjmu.edu.cn.; Department of Neurology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. linxiang1988@fjmu.edu.cn.; Fujian Key Laboratory of Molecular Neurology and Institute of Neuroscience, Fujian Medical University, Fuzhou, China. linxiang1988@fjmu.edu.cn., Hu J; Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China. fmrihjp@163.com.; Department of Radiology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. fmrihjp@163.com., Liu Y; Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China. liuying840102@163.com.; Department of Radiology, Fujian Key Laboratory of Precision Medicine for Cancer, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. liuying840102@163.com.; Department of Radiology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. liuying840102@163.com.
Source: Neuroradiology [Neuroradiology] 2026 Jun 08. Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 1302751 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1920 (Electronic) Linking ISSN: 00283940 NLM ISO Abbreviation: Neuroradiology Subsets: MEDLINE
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  Data: An MRI-based radiomics model for precision subtyping of hereditary spastic paraplegia: discriminating SPG4 from SPG5.
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  Data: <searchLink fieldCode="AU" term="%22Huang+Z%22">Huang Z</searchLink>; School of medical imaging, Fujian Medical University, Fuzhou, China.; Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.; Department of Radiology, Fujian Key Laboratory of Precision Medicine for Cancer, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.; Department of Radiology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Yuan+L%22">Yuan L</searchLink>; School of medical imaging, Fujian Medical University, Fuzhou, China.; Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Wan+Y%22">Wan Y</searchLink>; School of medical imaging, Fujian Medical University, Fuzhou, China.; Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Yan+X%22">Yan X</searchLink>; Department of Neurology and Institute of Neurology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China.; Department of Neurology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Lin+X%22">Lin X</searchLink>; Department of Neurology and Institute of Neurology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China. linxiang1988@fjmu.edu.cn.; Department of Neurology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. linxiang1988@fjmu.edu.cn.; Fujian Key Laboratory of Molecular Neurology and Institute of Neuroscience, Fujian Medical University, Fuzhou, China. linxiang1988@fjmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Hu+J%22">Hu J</searchLink>; Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China. fmrihjp@163.com.; Department of Radiology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. fmrihjp@163.com.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Radiology, The First Affiliated Hospital of Fujian Medical University, Fuzhou, China. liuying840102@163.com.; Department of Radiology, Fujian Key Laboratory of Precision Medicine for Cancer, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. liuying840102@163.com.; Department of Radiology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China. liuying840102@163.com.
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              Text: 2026 Jun 08
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