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Targeting programmed cell death: a novel therapeutic paradigm for cancer based on mode-of-death classification.

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Title: Targeting programmed cell death: a novel therapeutic paradigm for cancer based on mode-of-death classification.
Authors: Qiao X; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; Henan Provincial Engineering Center for Tumor Molecular Medicine, Kaifeng Key laboratory of cell signal transduction, Henan University, Kaifeng, 475004, China., Ye T; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China., Wu T; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China., Han X; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China., Sun T; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China., Wang H; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China., Jia J; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China., Dai Y; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China., Yun R; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China., Jiang S; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; Henan Provincial Engineering Center for Tumor Molecular Medicine, Kaifeng Key laboratory of cell signal transduction, Henan University, Kaifeng, 475004, China., Qin Y; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; Henan Provincial Engineering Center for Tumor Molecular Medicine, Kaifeng Key laboratory of cell signal transduction, Henan University, Kaifeng, 475004, China., Liu Z; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; Henan Provincial Engineering Center for Tumor Molecular Medicine, Kaifeng Key laboratory of cell signal transduction, Henan University, Kaifeng, 475004, China., An Y; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China. anyang@henu.edu.cn.; Henan Provincial Engineering Center for Tumor Molecular Medicine, Kaifeng Key laboratory of cell signal transduction, Henan University, Kaifeng, 475004, China. anyang@henu.edu.cn., Ji X; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China. 10190096@vip.henu.edu.cn.; Department of Nuclear Medicine, Department of Neurosurgery, The First Affiliated Hospital of Henan University, Henan University, Kaifeng, 475004, China. 10190096@vip.henu.edu.cn.; Henan Provincial Research Center of Engineering Technology for Nuclear Protein Medical Detection, Department of Microbiology and Immunology, Medical School of Health, Zhengzhou Health College, Zhengzhou, 450064, Henan, China. 10190096@vip.henu.edu.cn., Lv S; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China. shuangyulv@henu.edu.cn.; Department of Nuclear Medicine, Department of Neurosurgery, The First Affiliated Hospital of Henan University, Henan University, Kaifeng, 475004, China. shuangyulv@henu.edu.cn.; The Zhongzhou Laboratory for Integrative Biology, Zhengzhou, 450046, Henan, China. shuangyulv@henu.edu.cn.
Source: Apoptosis : an international journal on programmed cell death [Apoptosis] 2026 Jun 08; Vol. 31 (6). Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 9712129 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-675X (Electronic) Linking ISSN: 13608185 NLM ISO Abbreviation: Apoptosis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting programmed cell death: a novel therapeutic paradigm for cancer based on mode-of-death classification.
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  Data: <searchLink fieldCode="AU" term="%22Qiao+X%22">Qiao X</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; Henan Provincial Engineering Center for Tumor Molecular Medicine, Kaifeng Key laboratory of cell signal transduction, Henan University, Kaifeng, 475004, China.<br /><searchLink fieldCode="AU" term="%22Ye+T%22">Ye T</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China.<br /><searchLink fieldCode="AU" term="%22Wu+T%22">Wu T</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China.<br /><searchLink fieldCode="AU" term="%22Han+X%22">Han X</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China.<br /><searchLink fieldCode="AU" term="%22Sun+T%22">Sun T</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China.<br /><searchLink fieldCode="AU" term="%22Jia+J%22">Jia J</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China.<br /><searchLink fieldCode="AU" term="%22Dai+Y%22">Dai Y</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China.<br /><searchLink fieldCode="AU" term="%22Yun+R%22">Yun R</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; School of Stomatology, Henan University, Kaifeng, 475004, China.<br /><searchLink fieldCode="AU" term="%22Jiang+S%22">Jiang S</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; Henan Provincial Engineering Center for Tumor Molecular Medicine, Kaifeng Key laboratory of cell signal transduction, Henan University, Kaifeng, 475004, China.<br /><searchLink fieldCode="AU" term="%22Qin+Y%22">Qin Y</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; Henan Provincial Engineering Center for Tumor Molecular Medicine, Kaifeng Key laboratory of cell signal transduction, Henan University, Kaifeng, 475004, China.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China.; Henan Provincial Engineering Center for Tumor Molecular Medicine, Kaifeng Key laboratory of cell signal transduction, Henan University, Kaifeng, 475004, China.<br /><searchLink fieldCode="AU" term="%22An+Y%22">An Y</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China. anyang@henu.edu.cn.; Henan Provincial Engineering Center for Tumor Molecular Medicine, Kaifeng Key laboratory of cell signal transduction, Henan University, Kaifeng, 475004, China. anyang@henu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Ji+X%22">Ji X</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China. 10190096@vip.henu.edu.cn.; Department of Nuclear Medicine, Department of Neurosurgery, The First Affiliated Hospital of Henan University, Henan University, Kaifeng, 475004, China. 10190096@vip.henu.edu.cn.; Henan Provincial Research Center of Engineering Technology for Nuclear Protein Medical Detection, Department of Microbiology and Immunology, Medical School of Health, Zhengzhou Health College, Zhengzhou, 450064, Henan, China. 10190096@vip.henu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Lv+S%22">Lv S</searchLink>; Henan International Joint Laboratory of Nuclear Protein Regulation, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Henan University, Kaifeng, 475004, China. shuangyulv@henu.edu.cn.; Department of Nuclear Medicine, Department of Neurosurgery, The First Affiliated Hospital of Henan University, Henan University, Kaifeng, 475004, China. shuangyulv@henu.edu.cn.; The Zhongzhou Laboratory for Integrative Biology, Zhengzhou, 450046, Henan, China. shuangyulv@henu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229712129%22">Apoptosis : an international journal on programmed cell death</searchLink> [Apoptosis] 2026 Jun 08; Vol. 31 (6). <i>Date of Electronic Publication: </i>2026 Jun 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9712129 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-675X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213608185%22">13608185 </searchLink><i>NLM ISO Abbreviation: </i>Apoptosis <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s10495-026-02324-z
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      – Code: eng
        Text: English
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      – TitleFull: Targeting programmed cell death: a novel therapeutic paradigm for cancer based on mode-of-death classification.
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            – D: 08
              M: 06
              Text: 2026 Jun 08
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              Y: 2026
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            – TitleFull: Apoptosis : an international journal on programmed cell death
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