Psychedelics disrupt hierarchical cortical propagations in the default mode network of humans and mice.

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Bibliographic Details
Title: Psychedelics disrupt hierarchical cortical propagations in the default mode network of humans and mice.
Authors: Pines AR; Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94305., Zhang X; Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94305., Kochalka J; Department of Bioengineering, Stanford University, Palo Alto, CA 94305., Vesuna SS; Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94305.; Department of Bioengineering, Stanford University, Palo Alto, CA 94305., Kauvar IV; Department of Bioengineering, Stanford University, Palo Alto, CA 94305.; Department of Education, Graduate School of Education, Stanford University, Palo Alto, CA 94305., Rajasekharan D; Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94305., Reneau TR; Department of Radiology, Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, MO 63110., Akiki TJ; Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94305., Hack LM; Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94305.; Sierra-Pacific Mental Illness Research, Education and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304., Siegel JS; Department of Psychiatry, New York University, Langone Center for Psychedelic Medicine, New York University Grossman School of Medicine, New York, NY 10016.; Nathan Kline Institute for Psychiatric Research, New York, NY 10962., Williams LM; Department of Psychiatry and Behavioral Sciences, Stanford University, Palo Alto, CA 94305.; Sierra-Pacific Mental Illness Research, Education and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Jun 16; Vol. 123 (24), pp. e2522000123. Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.2522000123