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Polycythemia, SGLT2 inhibitors, and associated outcomes across the cardio-kidney-metabolic spectrum: a pooled analysis of randomized trials.

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Title: Polycythemia, SGLT2 inhibitors, and associated outcomes across the cardio-kidney-metabolic spectrum: a pooled analysis of randomized trials.
Authors: Marques P; RISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal; Department of Internal Medicine, Unidade Local de Saúde São João, Porto, Portugal; Division of Cardiology, McGill University Health Centre, Montreal, QC, Canada. Electronic address: pmmarques@med.up.pt., Vasques-Nóvoa F; RISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal; Department of Internal Medicine, Unidade Local de Saúde São João, Porto, Portugal., Pintalhão M; RISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal; Department of Internal Medicine, Unidade Local de Saúde São João, Porto, Portugal., Bergantim R; Department of Hematology, Unidade Local de Saúde São João, Porto, Portugal., Mendonça L; Department of Nephrology, Unidade Local de Saúde São João, Porto, Portugal., Neves JS; Department of Endocrinology, Unidade Local de Saúde São João, Porto, Portugal., Friões F; Department of Internal Medicine, Unidade Local de Saúde São João, Porto, Portugal; Department of Medicine, Faculdade de Medicina da Universidade do Porto, Portugal., Sharma A; Division of Cardiology, McGill University Health Centre, Montreal, QC, Canada; Research Institute of the McGill University Health Centre, McGill University, Montreal, Quebec, Canada., Filipatos G; National and Kapodistrian University of Athens School of Medicine, Athens, University Hospital Attikon, Athens, Greece., Butler J; Baylor Scott and White Research Institute, Dallas, TX and University of Mississippi, Jackson Mississippi, USA., Anker S; Department of Cardiology (CVK) of German Heart Center Charité; German Centre for Cardiovascular Research (DZHK) partner site Berlin, Charité Universitätsmedizin, Berlin, Germany., Zannad F; Université de Lorraine, INSERM, Centre d'Investigations Cliniques, CHRU de Nancy, Inserm and INI-CRCT (Cardiovascular and Renal Clinical Trialists) F-CRIN, Network, Nancy, France., Packer M; Baylor University Medical Center, Dallas, Texas, USA; Imperial College, London, UK., Ferreira JP; RISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal; Université de Lorraine, INSERM, Centre d'Investigations Cliniques, CHRU de Nancy, Inserm and INI-CRCT (Cardiovascular and Renal Clinical Trialists) F-CRIN, Network, Nancy, France. Electronic address: jpferreira@med.up.pt.
Source: European journal of internal medicine [Eur J Intern Med] 2026 Jun 08, pp. 106989. Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 9003220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0828 (Electronic) Linking ISSN: 09536205 NLM ISO Abbreviation: Eur J Intern Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Marques+P%22">Marques P</searchLink>; RISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal; Department of Internal Medicine, Unidade Local de Saúde São João, Porto, Portugal; Division of Cardiology, McGill University Health Centre, Montreal, QC, Canada. Electronic address: pmmarques@med.up.pt.<br /><searchLink fieldCode="AU" term="%22Vasques-Nóvoa+F%22">Vasques-Nóvoa F</searchLink>; RISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal; Department of Internal Medicine, Unidade Local de Saúde São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Pintalhão+M%22">Pintalhão M</searchLink>; RISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal; Department of Internal Medicine, Unidade Local de Saúde São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Bergantim+R%22">Bergantim R</searchLink>; Department of Hematology, Unidade Local de Saúde São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Mendonça+L%22">Mendonça L</searchLink>; Department of Nephrology, Unidade Local de Saúde São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Neves+JS%22">Neves JS</searchLink>; Department of Endocrinology, Unidade Local de Saúde São João, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Friões+F%22">Friões F</searchLink>; Department of Internal Medicine, Unidade Local de Saúde São João, Porto, Portugal; Department of Medicine, Faculdade de Medicina da Universidade do Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Sharma+A%22">Sharma A</searchLink>; Division of Cardiology, McGill University Health Centre, Montreal, QC, Canada; Research Institute of the McGill University Health Centre, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Filipatos+G%22">Filipatos G</searchLink>; National and Kapodistrian University of Athens School of Medicine, Athens, University Hospital Attikon, Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Butler+J%22">Butler J</searchLink>; Baylor Scott and White Research Institute, Dallas, TX and University of Mississippi, Jackson Mississippi, USA.<br /><searchLink fieldCode="AU" term="%22Anker+S%22">Anker S</searchLink>; Department of Cardiology (CVK) of German Heart Center Charité; German Centre for Cardiovascular Research (DZHK) partner site Berlin, Charité Universitätsmedizin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Zannad+F%22">Zannad F</searchLink>; Université de Lorraine, INSERM, Centre d'Investigations Cliniques, CHRU de Nancy, Inserm and INI-CRCT (Cardiovascular and Renal Clinical Trialists) F-CRIN, Network, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Packer+M%22">Packer M</searchLink>; Baylor University Medical Center, Dallas, Texas, USA; Imperial College, London, UK.<br /><searchLink fieldCode="AU" term="%22Ferreira+JP%22">Ferreira JP</searchLink>; RISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal; Université de Lorraine, INSERM, Centre d'Investigations Cliniques, CHRU de Nancy, Inserm and INI-CRCT (Cardiovascular and Renal Clinical Trialists) F-CRIN, Network, Nancy, France. Electronic address: jpferreira@med.up.pt.
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