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Efficacy and Safety Profile of a Triple Single-Pill Combination of Valsartan/Amlodipine/Chlorthalidone in Patients with Uncontrolled Hypertension.

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Title: Efficacy and Safety Profile of a Triple Single-Pill Combination of Valsartan/Amlodipine/Chlorthalidone in Patients with Uncontrolled Hypertension.
Authors: Lee HY; Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea., Suh SY; Division of Cardiology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea., Youn HJ; Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea., Chung WB; Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea., Han KH; Division of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Ahn Y; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University College of Medicine, Gwangju, Korea., Cha DH; Department of Cardiology, CHA University Bundang Medical Center, Seongnam, Korea., Kim SH; Division of Cardiology, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea., Park JS; Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea., Kim CK; Department/Division of Cardiology, Ewha Womans University Seoul Hospital (Medical Center), Ewha Womans University College of Medicine, Seoul, Korea., Kim JS; Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea., Shin JH; Division of Cardiology, Department of Internal Medicine, Hanyang University Seoul Hospital, Hanyang University College of Medicine, Seoul, Korea., Yoon MH; Department of Cardiology, Ajou University School of Medicine, Suwon, Korea., Lee JB; Department/Division of Cardiology, Daegu Catholic University Medical Center, Daegu, Korea., Kim JH; Division of Cardiology, Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea., Jeon DS; Division of Cardiology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea., Yu CW; Division of Cardiology, Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea., Kim MH; Department of Cardiology, Busan Regional CardioCerebroVascular Center, Dong‑A University Hospital, Busan, Korea., Lim KH; Department of Cardiology, Busan Regional CardioCerebroVascular Center, Dong‑A University Hospital, Busan, Korea., Sohn IS; Department of Cardiology, Kyung Hee University Hospital at Gangdong, Seoul, Korea., Jeong JO; Division of Cardiology, Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea., Park CG; Cardiovascular Center, Division of Cardiology, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea., Choi YJ; Cardiovascular Center, Division of Cardiology, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea., Lee CH; Division of Cardiology, Department of Internal Medicine, Veterans Health Service Medical Center, Seoul, Republic of Korea., Jeong J; Division of Cardiology, Department of Internal Medicine, Chosun University Hospital, Chosun University College of Medicine, Gwangju, Korea., Yoon SB; Department of Cardiology, H‑Plus Yangji Hospital, Seoul, Korea., Kwon SU; Division of Cardiology, Department of Internal Medicine, Inje University Busan Paik Hospital, Inje University College of Medicine, Korea., Yeo SH; KyungDong Pharmaceutical Co., Ltd., R&D Center, Hwaseong, Korea., Kim CJ; Division of Cardiology, Department of Internal Medicine, CHA Gangnam Medical Center, Seoul, Korea. Electronic address: chongjinkim@naver.com.
Source: Clinical therapeutics [Clin Ther] 2026 Jun 08. Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Excerpta Medica Country of Publication: United States NLM ID: 7706726 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-114X (Electronic) Linking ISSN: 01492918 NLM ISO Abbreviation: Clin Ther Subsets: MEDLINE
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  Data: Efficacy and Safety Profile of a Triple Single-Pill Combination of Valsartan/Amlodipine/Chlorthalidone in Patients with Uncontrolled Hypertension.
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  Data: <searchLink fieldCode="AU" term="%22Lee+HY%22">Lee HY</searchLink>; Division of Cardiology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Suh+SY%22">Suh SY</searchLink>; Division of Cardiology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea.<br /><searchLink fieldCode="AU" term="%22Youn+HJ%22">Youn HJ</searchLink>; Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Chung+WB%22">Chung WB</searchLink>; Division of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Han+KH%22">Han KH</searchLink>; Division of Cardiology, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+Y%22">Ahn Y</searchLink>; Division of Cardiology, Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University College of Medicine, Gwangju, Korea.<br /><searchLink fieldCode="AU" term="%22Cha+DH%22">Cha DH</searchLink>; Department of Cardiology, CHA University Bundang Medical Center, Seongnam, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SH%22">Kim SH</searchLink>; Division of Cardiology, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea.<br /><searchLink fieldCode="AU" term="%22Park+JS%22">Park JS</searchLink>; Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+CK%22">Kim CK</searchLink>; Department/Division of Cardiology, Ewha Womans University Seoul Hospital (Medical Center), Ewha Womans University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JS%22">Kim JS</searchLink>; Division of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Shin+JH%22">Shin JH</searchLink>; Division of Cardiology, Department of Internal Medicine, Hanyang University Seoul Hospital, Hanyang University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+MH%22">Yoon MH</searchLink>; Department of Cardiology, Ajou University School of Medicine, Suwon, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JB%22">Lee JB</searchLink>; Department/Division of Cardiology, Daegu Catholic University Medical Center, Daegu, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+JH%22">Kim JH</searchLink>; Division of Cardiology, Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.<br /><searchLink fieldCode="AU" term="%22Jeon+DS%22">Jeon DS</searchLink>; Division of Cardiology, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.<br /><searchLink fieldCode="AU" term="%22Yu+CW%22">Yu CW</searchLink>; Division of Cardiology, Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+MH%22">Kim MH</searchLink>; Department of Cardiology, Busan Regional CardioCerebroVascular Center, Dong‑A University Hospital, Busan, Korea.<br /><searchLink fieldCode="AU" term="%22Lim+KH%22">Lim KH</searchLink>; Department of Cardiology, Busan Regional CardioCerebroVascular Center, Dong‑A University Hospital, Busan, Korea.<br /><searchLink fieldCode="AU" term="%22Sohn+IS%22">Sohn IS</searchLink>; Department of Cardiology, Kyung Hee University Hospital at Gangdong, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+JO%22">Jeong JO</searchLink>; Division of Cardiology, Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University College of Medicine, Daejeon, Korea.<br /><searchLink fieldCode="AU" term="%22Park+CG%22">Park CG</searchLink>; Cardiovascular Center, Division of Cardiology, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Choi+YJ%22">Choi YJ</searchLink>; Cardiovascular Center, Division of Cardiology, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+CH%22">Lee CH</searchLink>; Division of Cardiology, Department of Internal Medicine, Veterans Health Service Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Jeong+J%22">Jeong J</searchLink>; Division of Cardiology, Department of Internal Medicine, Chosun University Hospital, Chosun University College of Medicine, Gwangju, Korea.<br /><searchLink fieldCode="AU" term="%22Yoon+SB%22">Yoon SB</searchLink>; Department of Cardiology, H‑Plus Yangji Hospital, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+SU%22">Kwon SU</searchLink>; Division of Cardiology, Department of Internal Medicine, Inje University Busan Paik Hospital, Inje University College of Medicine, Korea.<br /><searchLink fieldCode="AU" term="%22Yeo+SH%22">Yeo SH</searchLink>; KyungDong Pharmaceutical Co., Ltd., R&D Center, Hwaseong, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+CJ%22">Kim CJ</searchLink>; Division of Cardiology, Department of Internal Medicine, CHA Gangnam Medical Center, Seoul, Korea. Electronic address: chongjinkim@naver.com.
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