GPR15-guided CD8+ T regulatory cells control intestinal inflammation.
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| Title: | GPR15-guided CD8+ T regulatory cells control intestinal inflammation. |
|---|---|
| Authors: | Cui J; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.; Calico Life Sciences, South San Francisco, CA, USA., Chen Z; Experimental Immunology Branch, National Cancer Institute (NCI), NIH, Bethesda, MD, USA., Cheng YH; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA., Nie J; Laboratory of Immune Cell Biology and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA., Zhu MH; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA., Xiang C; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA., Chauvin S; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Lassoued W; Center for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA., Liu C; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.; Program in Biological Sciences, University of Maryland, College Park, MD, USA., Padhan K; Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA., Song J; Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA., Pai JA; Calico Life Sciences, South San Francisco, CA, USA., Ocón B; Laboratory of Immunology and Vascular Biology, Department of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.; Palo Alto Veterans Institute for Research, Palo Alto, CA, USA.; Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA., Yang Y; Division of Intramural Research, National Library of Medicine, NIH, Bethesda, MD, USA., Yao Y; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA., Park AY; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA., Gabrielski JQ; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA., Zheng L; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.; Calico Life Sciences, South San Francisco, CA, USA., Jiang PD; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA., Zhang Y; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.; Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA., Jing H; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.; Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA., Xu L; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA., Chen V; Integrated Data Sciences Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA., Calabresi BA; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA., Pittaluga S; Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA., Kleiner DE; Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA., Dalgard CL; Department of Anatomy, Physiology and Genetics, Uniformed Services University, Bethesda, MD, USA.; Center for Military Precision Health, The American Genome Center, Uniformed Services University, Bethesda, MD, USA., Sari S; Department of Pediatric Gastroenterology, Gazi University Faculty of Medicine, Ankara, Türkiye., Can S; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye.; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye., Karakoc-Aydiner E; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye.; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye., Baris S; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye.; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye., Erman B; Institute of Child Health, Can Sucak Research Laboratory for Translational Immunology, Hacettepe University, Ankara, Türkiye., Field M; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Silvester JA; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Saccocia G; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Buhamrah EK; Pediatric Gastroenterology and Hepatology Department, Al-Amiri Hospital, Kuwait City, Kuwait., Husain K; Pediatric Gastroenterology, Hepatology and Nutrition Department, Dar Al Shifa Hospital, Kuwait City, Kuwait., Chavoshzadeh Z; Allergy and Clinical Immunology Department, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran., Rezaei N; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran., İşlek A; Cukurova University Faculty of Medicine, Department of Pediatrics, Division of Gastroenterology and Hepatology, Adana, Türkiye., Baş H; Intergen Genetics and Rare Diseases Diagnosis Center, Ankara, Türkiye., Devrez FD; Intergen Genetics and Rare Diseases Diagnosis Center, Ankara, Türkiye., Mackeh R; Translational Medicine Department, Research Department, Sidra Medicine, Doha, Qatar., Fuss IJ; Mucosal Immunity Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA., Reich DS; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA., Bailey S; Center for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA., Sater HA; Center for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA., Gulley JL; Center for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA., Kabat J; Biological Imaging Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA., Smelkinson M; Biological Imaging Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA., Ganesan S; Biological Imaging Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA., Chen Z; Calico Life Sciences, South San Francisco, CA, USA., Grayson PC; Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal, and Skin Diseases, NIH, Bethesda, MD, USA., Redekar N; Integrated Data Sciences Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA., Lack J; Integrated Data Sciences Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA., Lu Z; Division of Intramural Research, National Library of Medicine, NIH, Bethesda, MD, USA., Lo B; Translational Medicine Department, Research Department, Sidra Medicine, Doha, Qatar.; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar., Abolhassani H; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.; Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.; Clinic for Pediatric Immunology and Rheumatology, Center for Pediatrics and Adolescent Medicine, University Hospital Bonn, Bonn, Germany., Ozen A; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye.; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye., Bousvaros A; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Snapper SB; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA., Butcher EC; Laboratory of Immunology and Vascular Biology, Department of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.; Palo Alto Veterans Institute for Research, Palo Alto, CA, USA.; Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA., Ravell J; Division of Allergy and Immunology, Department of Internal Medicine, Hackensack University Medical Center, Hackensack, NJ, USA.; Department of Internal Medicine, Hackensack Meridian School of Medicine, Nutley, NJ, USA., Bosselut R; Laboratory of Immune Cell Biology and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA., Su HC; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.; Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA., Wu C; Experimental Immunology Branch, National Cancer Institute (NCI), NIH, Bethesda, MD, USA. chuan.wu@nih.gov., Lenardo MJ; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA. lenardo@calicolabs.com.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA. lenardo@calicolabs.com.; Calico Life Sciences, South San Francisco, CA, USA. lenardo@calicolabs.com. |
| Source: | Nature [Nature] 2026 Jun 08. Date of Electronic Publication: 2026 Jun 08. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42259915 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: GPR15-guided CD8<superscript>+</superscript> T regulatory cells control intestinal inflammation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Cui+J%22">Cui J</searchLink>; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.; Calico Life Sciences, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Experimental Immunology Branch, National Cancer Institute (NCI), NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Cheng+YH%22">Cheng YH</searchLink>; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Nie+J%22">Nie J</searchLink>; Laboratory of Immune Cell Biology and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+MH%22">Zhu MH</searchLink>; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Xiang+C%22">Xiang C</searchLink>; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chauvin+S%22">Chauvin S</searchLink>; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Lassoued+W%22">Lassoued W</searchLink>; Center for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Multiscale Systems Biology Section, Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.; Program in Biological Sciences, University of Maryland, College Park, MD, USA.<br /><searchLink fieldCode="AU" term="%22Padhan+K%22">Padhan K</searchLink>; Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Song+J%22">Song J</searchLink>; Laboratory of Immune System Biology, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Pai+JA%22">Pai JA</searchLink>; Calico Life Sciences, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ocón+B%22">Ocón B</searchLink>; Laboratory of Immunology and Vascular Biology, Department of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.; Palo Alto Veterans Institute for Research, Palo Alto, CA, USA.; Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Division of Intramural Research, National Library of Medicine, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Yao+Y%22">Yao Y</searchLink>; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Park+AY%22">Park AY</searchLink>; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gabrielski+JQ%22">Gabrielski JQ</searchLink>; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Zheng+L%22">Zheng L</searchLink>; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.; Calico Life Sciences, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Jiang+PD%22">Jiang PD</searchLink>; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.; Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Jing+H%22">Jing H</searchLink>; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.; Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Xu+L%22">Xu L</searchLink>; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chen+V%22">Chen V</searchLink>; Integrated Data Sciences Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Calabresi+BA%22">Calabresi BA</searchLink>; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Pittaluga+S%22">Pittaluga S</searchLink>; Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kleiner+DE%22">Kleiner DE</searchLink>; Laboratory of Pathology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Dalgard+CL%22">Dalgard CL</searchLink>; Department of Anatomy, Physiology and Genetics, Uniformed Services University, Bethesda, MD, USA.; Center for Military Precision Health, The American Genome Center, Uniformed Services University, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sari+S%22">Sari S</searchLink>; Department of Pediatric Gastroenterology, Gazi University Faculty of Medicine, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Can+S%22">Can S</searchLink>; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye.; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Karakoc-Aydiner+E%22">Karakoc-Aydiner E</searchLink>; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye.; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Baris+S%22">Baris S</searchLink>; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye.; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Erman+B%22">Erman B</searchLink>; Institute of Child Health, Can Sucak Research Laboratory for Translational Immunology, Hacettepe University, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Field+M%22">Field M</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Silvester+JA%22">Silvester JA</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Saccocia+G%22">Saccocia G</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Buhamrah+EK%22">Buhamrah EK</searchLink>; Pediatric Gastroenterology and Hepatology Department, Al-Amiri Hospital, Kuwait City, Kuwait.<br /><searchLink fieldCode="AU" term="%22Husain+K%22">Husain K</searchLink>; Pediatric Gastroenterology, Hepatology and Nutrition Department, Dar Al Shifa Hospital, Kuwait City, Kuwait.<br /><searchLink fieldCode="AU" term="%22Chavoshzadeh+Z%22">Chavoshzadeh Z</searchLink>; Allergy and Clinical Immunology Department, Mofid Children Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Rezaei+N%22">Rezaei N</searchLink>; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22İşlek+A%22">İşlek A</searchLink>; Cukurova University Faculty of Medicine, Department of Pediatrics, Division of Gastroenterology and Hepatology, Adana, Türkiye.<br /><searchLink fieldCode="AU" term="%22Baş+H%22">Baş H</searchLink>; Intergen Genetics and Rare Diseases Diagnosis Center, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Devrez+FD%22">Devrez FD</searchLink>; Intergen Genetics and Rare Diseases Diagnosis Center, Ankara, Türkiye.<br /><searchLink fieldCode="AU" term="%22Mackeh+R%22">Mackeh R</searchLink>; Translational Medicine Department, Research Department, Sidra Medicine, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Fuss+IJ%22">Fuss IJ</searchLink>; Mucosal Immunity Section, Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Reich+DS%22">Reich DS</searchLink>; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Bailey+S%22">Bailey S</searchLink>; Center for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sater+HA%22">Sater HA</searchLink>; Center for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Gulley+JL%22">Gulley JL</searchLink>; Center for Immuno-Oncology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Kabat+J%22">Kabat J</searchLink>; Biological Imaging Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Smelkinson+M%22">Smelkinson M</searchLink>; Biological Imaging Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ganesan+S%22">Ganesan S</searchLink>; Biological Imaging Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Calico Life Sciences, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Grayson+PC%22">Grayson PC</searchLink>; Vasculitis Translational Research Program, National Institute of Arthritis and Musculoskeletal, and Skin Diseases, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Redekar+N%22">Redekar N</searchLink>; Integrated Data Sciences Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lack+J%22">Lack J</searchLink>; Integrated Data Sciences Section, Research Technologies Branch, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lu+Z%22">Lu Z</searchLink>; Division of Intramural Research, National Library of Medicine, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lo+B%22">Lo B</searchLink>; Translational Medicine Department, Research Department, Sidra Medicine, Doha, Qatar.; College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Abolhassani+H%22">Abolhassani H</searchLink>; Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.; Division of Immunology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.; Clinic for Pediatric Immunology and Rheumatology, Center for Pediatrics and Adolescent Medicine, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Ozen+A%22">Ozen A</searchLink>; Department of Pediatrics, Division of Allergy and Immunology, Marmara University, School of Medicine, Istanbul, Türkiye.; The Istanbul Jeffrey Modell Diagnostic Center for Primary Immunodeficiency Diseases, Istanbul, Türkiye.; The Isil Berat Barlan Center for Translational Medicine, Istanbul, Türkiye.<br /><searchLink fieldCode="AU" term="%22Bousvaros+A%22">Bousvaros A</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Snapper+SB%22">Snapper SB</searchLink>; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Butcher+EC%22">Butcher EC</searchLink>; Laboratory of Immunology and Vascular Biology, Department of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.; Palo Alto Veterans Institute for Research, Palo Alto, CA, USA.; Veterans Affairs Palo Alto Health Care System, Palo Alto, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ravell+J%22">Ravell J</searchLink>; Division of Allergy and Immunology, Department of Internal Medicine, Hackensack University Medical Center, Hackensack, NJ, USA.; Department of Internal Medicine, Hackensack Meridian School of Medicine, Nutley, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Bosselut+R%22">Bosselut R</searchLink>; Laboratory of Immune Cell Biology and Laboratory of Integrative Cancer Immunology, Center for Cancer Research, NCI, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Su+HC%22">Su HC</searchLink>; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA.; Laboratory of Clinical Immunology and Microbiology, NIAID, NIH, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wu+C%22">Wu C</searchLink>; Experimental Immunology Branch, National Cancer Institute (NCI), NIH, Bethesda, MD, USA. chuan.wu@nih.gov.<br /><searchLink fieldCode="AU" term="%22Lenardo+MJ%22">Lenardo MJ</searchLink>; Molecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA. lenardo@calicolabs.com.; Clinical Genomics Program, NIAID, NIH, Bethesda, MD, USA. lenardo@calicolabs.com.; Calico Life Sciences, South San Francisco, CA, USA. lenardo@calicolabs.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2026 Jun 08. <i>Date of Electronic Publication: </i>2026 Jun 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0410462 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4687 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200280836%22">00280836 </searchLink><i>NLM ISO Abbreviation: </i>Nature <i>Subsets: </i>MEDLINE |
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