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A cross-species atlas of the dorsal vagal complex reveals neural mediators of the effects of cagrilintide on energy balance.

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Title: A cross-species atlas of the dorsal vagal complex reveals neural mediators of the effects of cagrilintide on energy balance.
Authors: Ludwig MQ; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.; Research and Development, Novo Nordisk, Måløv, Denmark., Coester B; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Gordian D; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA., Hassan S; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Tomlinson AJ; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA., Toure MH; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA., Christensen OP; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.; Pioneer Centre for SMARTbiomed, University of Copenhagen, Copenhagen, Denmark., Lommi G; Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Zurich, Switzerland., Moltke-Prehn A; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Brown JM; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Belmont-Rausch DM; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Bau S; Research and Development, Novo Nordisk, Måløv, Denmark., Bodur C; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA., Gowda A; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA., Wu I; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA., Kernodle S; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA., Dong V; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA., Ayensu-Mensah M; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA., Sabatini PV; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA.; Department of Medicine, McGill University, Montreal, Quebec, Canada., Shin JH; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA., Kirigiti M; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA., Egerod KL; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark., Le Foll C; Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Zurich, Switzerland., Lundh S; Research and Development, Novo Nordisk, Måløv, Denmark., Gerstenberg MK; Research and Development, Novo Nordisk, Måløv, Denmark., Lutz TA; Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Zurich, Switzerland.; One Health Institute, University of Zurich, Zurich, Switzerland., Kievit P; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA., Secher A; Research and Development, Novo Nordisk, Måløv, Denmark., Raun K; Research and Development, Novo Nordisk, Måløv, Denmark., Myers MG Jr; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA., Pers TH; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark. tune.pers@sund.ku.dk.; Pioneer Centre for SMARTbiomed, University of Copenhagen, Copenhagen, Denmark. tune.pers@sund.ku.dk.
Source: Nature metabolism [Nat Metab] 2026 Jun; Vol. 8 (6), pp. 1350-1367. Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE
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  Data: A cross-species atlas of the dorsal vagal complex reveals neural mediators of the effects of cagrilintide on energy balance.
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  Data: <searchLink fieldCode="AU" term="%22Ludwig+MQ%22">Ludwig MQ</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.; Research and Development, Novo Nordisk, Måløv, Denmark.<br /><searchLink fieldCode="AU" term="%22Coester+B%22">Coester B</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Gordian+D%22">Gordian D</searchLink>; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Hassan+S%22">Hassan S</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Tomlinson+AJ%22">Tomlinson AJ</searchLink>; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Toure+MH%22">Toure MH</searchLink>; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Christensen+OP%22">Christensen OP</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.; Pioneer Centre for SMARTbiomed, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lommi+G%22">Lommi G</searchLink>; Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Moltke-Prehn+A%22">Moltke-Prehn A</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Brown+JM%22">Brown JM</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Belmont-Rausch+DM%22">Belmont-Rausch DM</searchLink>; 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Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Ayensu-Mensah+M%22">Ayensu-Mensah M</searchLink>; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Sabatini+PV%22">Sabatini PV</searchLink>; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA.; Department of Medicine, McGill University, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Shin+JH%22">Shin JH</searchLink>; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Kirigiti+M%22">Kirigiti M</searchLink>; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Egerod+KL%22">Egerod KL</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Le+Foll+C%22">Le Foll C</searchLink>; Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Lundh+S%22">Lundh S</searchLink>; Research and Development, Novo Nordisk, Måløv, Denmark.<br /><searchLink fieldCode="AU" term="%22Gerstenberg+MK%22">Gerstenberg MK</searchLink>; Research and Development, Novo Nordisk, Måløv, Denmark.<br /><searchLink fieldCode="AU" term="%22Lutz+TA%22">Lutz TA</searchLink>; Institute of Veterinary Physiology, Vetsuisse Faculty University of Zurich, Zurich, Switzerland.; One Health Institute, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kievit+P%22">Kievit P</searchLink>; Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.<br /><searchLink fieldCode="AU" term="%22Secher+A%22">Secher A</searchLink>; Research and Development, Novo Nordisk, Måløv, Denmark.<br /><searchLink fieldCode="AU" term="%22Raun+K%22">Raun K</searchLink>; Research and Development, Novo Nordisk, Måløv, Denmark.<br /><searchLink fieldCode="AU" term="%22Myers+MG+Jr%22">Myers MG Jr</searchLink>; Departments of Internal Medicine, University of Michigan and Molecular and Integrative Physiology, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Pers+TH%22">Pers TH</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark. tune.pers@sund.ku.dk.; Pioneer Centre for SMARTbiomed, University of Copenhagen, Copenhagen, Denmark. tune.pers@sund.ku.dk.
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  Data: <searchLink fieldCode="JN" term="%22101736592%22">Nature metabolism</searchLink> [Nat Metab] 2026 Jun; Vol. 8 (6), pp. 1350-1367. <i>Date of Electronic Publication: </i>2026 Jun 08.
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