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Chromatix: a differentiable, GPU-accelerated wave-optics library.

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Title: Chromatix: a differentiable, GPU-accelerated wave-optics library.
Authors: Deb D; HHMI Janelia Research Campus, Ashburn, VA, USA. debd@janelia.hhmi.org., Both GJ; HHMI Janelia Research Campus, Ashburn, VA, USA. bothg@janelia.hhmi.org., Bezzam E; Audiovisual Communications Laboratory, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Kohli A; Department of Electrical Engineering and Computer Sciences, UC Berkeley, Berkeley, CA, USA., Yang S; Chandra Family Department of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX, USA., Chaware A; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Allier C; HHMI Janelia Research Campus, Ashburn, VA, USA., Cai C; Department of Applied Physical Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Joint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Anderberg G; Department of Radiology, University of Chicago, Chicago, IL, USA., Eybposh MH; Department of Applied Physical Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Joint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Schneider MC; HHMI Janelia Research Campus, Ashburn, VA, USA., Heintzmann R; Leibniz Institute of Photonic Technology, Jena, Germany.; Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich-Schiller-Universität Jena, Jena, Germany., Rivera-Sanchez FA; Imaging Physics, Faculty of Applied Sciences, Technische Universiteit Delft, Delft, The Netherlands.; Advanced Research Center for Nanolithography (ARCNL), Amsterdam, The Netherlands., Simmerer C; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Meng G; Department of Electrical Engineering and Computer Sciences, UC Berkeley, Berkeley, CA, USA.; Herbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, CA, USA., Tormes-Vaquerano J; Department of Applied Physical Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Han S; Department of Applied Physics, Yale University, New Haven, CT, USA., Shanmugavel SC; Chandra Family Department of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX, USA., Maruvada T; Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, USA., Yang X; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Kim Y; Department of Mechanical Engineering, Yonsei University, Seoul, Republic of Korea., Diederich B; Leibniz Institute of Photonic Technology, Jena, Germany., Joo C; Department of Mechanical Engineering, Yonsei University, Seoul, Republic of Korea., Waller L; Department of Electrical Engineering and Computer Sciences, UC Berkeley, Berkeley, CA, USA., Durr NJ; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Pégard NC; Department of Applied Physical Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Joint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Carolina Stress Initiative, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., La Rivière PJ; Department of Radiology, University of Chicago, Chicago, IL, USA., Horstmeyer R; Department of Biomedical Engineering, Duke University, Durham, NC, USA., Chowdhury S; Chandra Family Department of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX, USA., Turaga SC; HHMI Janelia Research Campus, Ashburn, VA, USA. turagas@janelia.hhmi.org.
Source: Nature methods [Nat Methods] 2026 Jul; Vol. 23 (7), pp. 1388-1398. Date of Electronic Publication: 2026 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Deb+D%22">Deb D</searchLink>; HHMI Janelia Research Campus, Ashburn, VA, USA. debd@janelia.hhmi.org.<br /><searchLink fieldCode="AU" term="%22Both+GJ%22">Both GJ</searchLink>; HHMI Janelia Research Campus, Ashburn, VA, USA. bothg@janelia.hhmi.org.<br /><searchLink fieldCode="AU" term="%22Bezzam+E%22">Bezzam E</searchLink>; Audiovisual Communications Laboratory, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kohli+A%22">Kohli A</searchLink>; Department of Electrical Engineering and Computer Sciences, UC Berkeley, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Yang+S%22">Yang S</searchLink>; Chandra Family Department of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Chaware+A%22">Chaware A</searchLink>; Department of Biomedical Engineering, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Allier+C%22">Allier C</searchLink>; HHMI Janelia Research Campus, Ashburn, VA, USA.<br /><searchLink fieldCode="AU" term="%22Cai+C%22">Cai C</searchLink>; Department of Applied Physical Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Joint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Anderberg+G%22">Anderberg G</searchLink>; Department of Radiology, University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Eybposh+MH%22">Eybposh MH</searchLink>; Department of Applied Physical Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Joint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Schneider+MC%22">Schneider MC</searchLink>; HHMI Janelia Research Campus, Ashburn, VA, USA.<br /><searchLink fieldCode="AU" term="%22Heintzmann+R%22">Heintzmann R</searchLink>; Leibniz Institute of Photonic Technology, Jena, Germany.; Institute of Physical Chemistry and Abbe Center of Photonics, Friedrich-Schiller-Universität Jena, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Rivera-Sanchez+FA%22">Rivera-Sanchez FA</searchLink>; Imaging Physics, Faculty of Applied Sciences, Technische Universiteit Delft, Delft, The Netherlands.; Advanced Research Center for Nanolithography (ARCNL), Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Simmerer+C%22">Simmerer C</searchLink>; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Meng+G%22">Meng G</searchLink>; Department of Electrical Engineering and Computer Sciences, UC Berkeley, Berkeley, CA, USA.; Herbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tormes-Vaquerano+J%22">Tormes-Vaquerano J</searchLink>; Department of Applied Physical Sciences, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Han+S%22">Han S</searchLink>; Department of Applied Physics, Yale University, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Shanmugavel+SC%22">Shanmugavel SC</searchLink>; Chandra Family Department of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Maruvada+T%22">Maruvada T</searchLink>; Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Department of Biomedical Engineering, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Kim+Y%22">Kim Y</searchLink>; Department of Mechanical Engineering, Yonsei University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Diederich+B%22">Diederich B</searchLink>; Leibniz Institute of Photonic Technology, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Joo+C%22">Joo C</searchLink>; Department of Mechanical Engineering, Yonsei University, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Waller+L%22">Waller L</searchLink>; 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Chandra Family Department of Electrical and Computer Engineering, The University of Texas at Austin, Austin, TX, USA.<br /><searchLink fieldCode="AU" term="%22Turaga+SC%22">Turaga SC</searchLink>; HHMI Janelia Research Campus, Ashburn, VA, USA. turagas@janelia.hhmi.org.
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