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PTPN22 regulates T cell synapse formation through PSTPIP1-dependent actin remodeling.

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Title: PTPN22 regulates T cell synapse formation through PSTPIP1-dependent actin remodeling.
Authors: Joseph MD; London Centre for Nanotechnology, University College London, WC1H 0AH London, UK., Zaza C; London Centre for Nanotechnology, University College London, WC1H 0AH London, UK., Dalby OPL; London Centre for Nanotechnology, University College London, WC1H 0AH London, UK.; Department of Chemistry, University College London, WC1H 0AJ London, UK., Kirtsios E; Molecular and Cellular Immunology Section, Great Ormond Street Institute of Child Health, University College London, WC1N 1EH London, UK., Dustin ML; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences (NDORMS), University of Oxford, OX3 7FY Oxford, UK.; Chinese Academy of Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, OX3 7BN Oxford, UK., Cope AP; Centre for Inflammation Biology & Cancer Immunology, King's College London, New Hunt's House, SE1 9RT London, UK., Simoncelli S; London Centre for Nanotechnology, University College London, WC1H 0AH London, UK.; Department of Chemistry, University College London, WC1H 0AJ London, UK.
Source: Science signaling [Sci Signal] 2026 Jun 09; Vol. 19 (941), pp. eady6063. Date of Electronic Publication: 2026 Jun 09.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PTPN22 regulates T cell synapse formation through PSTPIP1-dependent actin remodeling.
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  Data: <searchLink fieldCode="AU" term="%22Joseph+MD%22">Joseph MD</searchLink>; London Centre for Nanotechnology, University College London, WC1H 0AH London, UK.<br /><searchLink fieldCode="AU" term="%22Zaza+C%22">Zaza C</searchLink>; London Centre for Nanotechnology, University College London, WC1H 0AH London, UK.<br /><searchLink fieldCode="AU" term="%22Dalby+OPL%22">Dalby OPL</searchLink>; London Centre for Nanotechnology, University College London, WC1H 0AH London, UK.; Department of Chemistry, University College London, WC1H 0AJ London, UK.<br /><searchLink fieldCode="AU" term="%22Kirtsios+E%22">Kirtsios E</searchLink>; Molecular and Cellular Immunology Section, Great Ormond Street Institute of Child Health, University College London, WC1N 1EH London, UK.<br /><searchLink fieldCode="AU" term="%22Dustin+ML%22">Dustin ML</searchLink>; Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, Rheumatology, and Musculoskeletal Sciences (NDORMS), University of Oxford, OX3 7FY Oxford, UK.; Chinese Academy of Medical Sciences Oxford Institute, Nuffield Department of Medicine, University of Oxford, OX3 7BN Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Cope+AP%22">Cope AP</searchLink>; Centre for Inflammation Biology & Cancer Immunology, King's College London, New Hunt's House, SE1 9RT London, UK.<br /><searchLink fieldCode="AU" term="%22Simoncelli+S%22">Simoncelli S</searchLink>; London Centre for Nanotechnology, University College London, WC1H 0AH London, UK.; Department of Chemistry, University College London, WC1H 0AJ London, UK.
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  Data: <searchLink fieldCode="JN" term="%22101465400%22">Science signaling</searchLink> [Sci Signal] 2026 Jun 09; Vol. 19 (941), pp. eady6063. <i>Date of Electronic Publication: </i>2026 Jun 09.
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        Value: 10.1126/scisignal.ady6063
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      – TitleFull: PTPN22 regulates T cell synapse formation through PSTPIP1-dependent actin remodeling.
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              Text: 2026 Jun 09
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