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Early Identification of Differentiation Syndrome During ATRA and Arsenic Therapy in Pediatric NHR-APL: Insights From a 14-Year Multicenter Cohort.

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Title: Early Identification of Differentiation Syndrome During ATRA and Arsenic Therapy in Pediatric NHR-APL: Insights From a 14-Year Multicenter Cohort.
Authors: Fan Z; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Yang LC; Xiangya Hospital, Central South University, Changsha, China., Chen YQ; Fujian Medical University Union Hospital, Fuzhou, China., Wan WQ; Second Xiangya Hospital, Central South University, Changsha, China., Mai HR; Shenzhen Children's Hospital, Shenzhen, China., Yang LH; Zhujiang Hospital, Southern Medical University, Guangzhou, China., Lan HK; Zhujiang Hospital, Southern Medical University, Guangzhou, China., Zhou DH; Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China., Li WL; Hunan Children's Hospital, Changsha, China., Guo BY; First Affiliated Hospital of Xiamen University, Xiamen, China., He F; Jiangxi Children's Hospital, Nanchang, China., Liao LH; Huizhou Central People's Hospital, Huizhou, China., Chen HQ; Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China., Zhen ZJ; Sun Yat-sen University Cancer Center, Guangzhou, China., He XL; Hunan Provincial People's Hospital, Changsha, China., Feng XQ; Nanfang Hospital, Southern Medical University, Guangzhou, China., Chen GH; First People's Hospital of Huizhou, Huizhou, China., Ji XQ; Hainan Provincial People ' s Hospital, Haikou, China., Chen M; Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, China., Li QR; Zhongshan People's Hospital, Zhongshan, China., Long XJ; Liuzhou People's Hospital, Liuzhou, China., Tian C; First Affiliated Hospital, Guangdong Medical University, Zhanjiang, China., Fu Y; Shunde Women and Children's Hospital, Guangdong Medical University, Shunde, China., Huang XY; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Luo JS; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Huang DP; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Wang LN; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Li Y; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Li B; Biostatistics Team, Clinical Trials Unit, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Luo XQ; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Huang LB; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Tang YL; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China., Zhang XL; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Source: Pharmacoepidemiology and drug safety [Pharmacoepidemiol Drug Saf] 2026 Jun; Vol. 35 (6), pp. e70390.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 9208369 Publication Model: Print Cited Medium: Internet ISSN: 1099-1557 (Electronic) Linking ISSN: 10538569 NLM ISO Abbreviation: Pharmacoepidemiol Drug Saf Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Fan+Z%22">Fan Z</searchLink>; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Yang+LC%22">Yang LC</searchLink>; Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Chen+YQ%22">Chen YQ</searchLink>; Fujian Medical University Union Hospital, Fuzhou, China.<br /><searchLink fieldCode="AU" term="%22Wan+WQ%22">Wan WQ</searchLink>; Second Xiangya Hospital, Central South University, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Mai+HR%22">Mai HR</searchLink>; Shenzhen Children's Hospital, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Yang+LH%22">Yang LH</searchLink>; Zhujiang Hospital, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lan+HK%22">Lan HK</searchLink>; Zhujiang Hospital, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+DH%22">Zhou DH</searchLink>; Sun Yat-Sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+WL%22">Li WL</searchLink>; Hunan Children's Hospital, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Guo+BY%22">Guo BY</searchLink>; First Affiliated Hospital of Xiamen University, Xiamen, China.<br /><searchLink fieldCode="AU" term="%22He+F%22">He F</searchLink>; Jiangxi Children's Hospital, Nanchang, China.<br /><searchLink fieldCode="AU" term="%22Liao+LH%22">Liao LH</searchLink>; Huizhou Central People's Hospital, Huizhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+HQ%22">Chen HQ</searchLink>; Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhen+ZJ%22">Zhen ZJ</searchLink>; Sun Yat-sen University Cancer Center, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22He+XL%22">He XL</searchLink>; Hunan Provincial People's Hospital, Changsha, China.<br /><searchLink fieldCode="AU" term="%22Feng+XQ%22">Feng XQ</searchLink>; Nanfang Hospital, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+GH%22">Chen GH</searchLink>; First People's Hospital of Huizhou, Huizhou, China.<br /><searchLink fieldCode="AU" term="%22Ji+XQ%22">Ji XQ</searchLink>; Hainan Provincial People ' s Hospital, Haikou, China.<br /><searchLink fieldCode="AU" term="%22Chen+M%22">Chen M</searchLink>; Fifth Affiliated Hospital, Sun Yat-Sen University, Zhuhai, China.<br /><searchLink fieldCode="AU" term="%22Li+QR%22">Li QR</searchLink>; Zhongshan People's Hospital, Zhongshan, China.<br /><searchLink fieldCode="AU" term="%22Long+XJ%22">Long XJ</searchLink>; Liuzhou People's Hospital, Liuzhou, China.<br /><searchLink fieldCode="AU" term="%22Tian+C%22">Tian C</searchLink>; First Affiliated Hospital, Guangdong Medical University, Zhanjiang, China.<br /><searchLink fieldCode="AU" term="%22Fu+Y%22">Fu Y</searchLink>; Shunde Women and Children's Hospital, Guangdong Medical University, Shunde, China.<br /><searchLink fieldCode="AU" term="%22Huang+XY%22">Huang XY</searchLink>; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Luo+JS%22">Luo JS</searchLink>; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Huang+DP%22">Huang DP</searchLink>; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+LN%22">Wang LN</searchLink>; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+B%22">Li B</searchLink>; Biostatistics Team, Clinical Trials Unit, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Luo+XQ%22">Luo XQ</searchLink>; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Huang+LB%22">Huang LB</searchLink>; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Tang+YL%22">Tang YL</searchLink>; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+XL%22">Zhang XL</searchLink>; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9208369 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1099-1557 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210538569%22">10538569 </searchLink><i>NLM ISO Abbreviation: </i>Pharmacoepidemiol Drug Saf <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun
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