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GBP1 recruitment to actin-rich pedestals of extracellular Gram-negative bacteria promotes pyroptosis.

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Title: GBP1 recruitment to actin-rich pedestals of extracellular Gram-negative bacteria promotes pyroptosis.
Authors: Bennison DJ; Department of Infectious Disease, Imperial College London, London, UK., Chaudhary I; Department of Infectious Disease, Imperial College London, London, UK.; Indian Institute of Science Education and Research, Pune, India., Chaudhuri D; Department of Infectious Disease, Imperial College London, London, UK.; Department of Developmental Biology & Genetics, Indian Institute of Science, Bengaluru, India., Wong JCN; Department of Infectious Disease, Imperial College London, London, UK., Punwatkar A; Department of Infectious Disease, Imperial College London, London, UK., Biswas P; Department of Life Sciences, Imperial College London, London, UK., Stephenson M; Department of Infectious Disease, Imperial College London, London, UK., Zhong Q; Department of Infectious Disease, Imperial College London, London, UK., Kallemeijn WW; The Francis Crick Institute, London, UK.; Department of Chemistry, Imperial College London, London, UK., Guenot M; Department of Life Sciences, Imperial College London, London, UK., Koigi S; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London, UK., Papp D; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London, UK., Thomas JP; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.; UKRI MRC Laboratory of Medical Sciences, Hammersmith Hospital Campus, London, UK., Dixit D; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK., Korcsmaros T; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London, UK., Talman AM; MIVEGEC, University of Montpellier, IRD, CNRS, Montpellier, France., Frickel EM; Department of Microbiology and Molecular Medicine, University of Geneva, Geneva, Switzerland., Tate EW; The Francis Crick Institute, London, UK.; Department of Chemistry, Imperial College London, London, UK., Visweswariah SS; Department of Developmental Biology & Genetics, Indian Institute of Science, Bengaluru, India.; Department of Life Sciences, Imperial College London, London, UK., Frankel G; Department of Life Sciences, Imperial College London, London, UK., Shenoy AR; Department of Infectious Disease, Imperial College London, London, UK. a.shenoy@imperial.ac.uk.
Source: The EMBO journal [EMBO J] 2026 Jul; Vol. 45 (14), pp. 5046-5078. Date of Electronic Publication: 2026 Jun 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: GBP1 recruitment to actin-rich pedestals of extracellular Gram-negative bacteria promotes pyroptosis.
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  Data: <searchLink fieldCode="AU" term="%22Bennison+DJ%22">Bennison DJ</searchLink>; Department of Infectious Disease, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Chaudhary+I%22">Chaudhary I</searchLink>; Department of Infectious Disease, Imperial College London, London, UK.; Indian Institute of Science Education and Research, Pune, India.<br /><searchLink fieldCode="AU" term="%22Chaudhuri+D%22">Chaudhuri D</searchLink>; Department of Infectious Disease, Imperial College London, London, UK.; Department of Developmental Biology & Genetics, Indian Institute of Science, Bengaluru, India.<br /><searchLink fieldCode="AU" term="%22Wong+JCN%22">Wong JCN</searchLink>; Department of Infectious Disease, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Punwatkar+A%22">Punwatkar A</searchLink>; Department of Infectious Disease, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Biswas+P%22">Biswas P</searchLink>; Department of Life Sciences, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Stephenson+M%22">Stephenson M</searchLink>; Department of Infectious Disease, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Zhong+Q%22">Zhong Q</searchLink>; Department of Infectious Disease, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Kallemeijn+WW%22">Kallemeijn WW</searchLink>; The Francis Crick Institute, London, UK.; Department of Chemistry, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Guenot+M%22">Guenot M</searchLink>; Department of Life Sciences, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Koigi+S%22">Koigi S</searchLink>; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Papp+D%22">Papp D</searchLink>; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Thomas+JP%22">Thomas JP</searchLink>; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.; UKRI MRC Laboratory of Medical Sciences, Hammersmith Hospital Campus, London, UK.<br /><searchLink fieldCode="AU" term="%22Dixit+D%22">Dixit D</searchLink>; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.<br /><searchLink fieldCode="AU" term="%22Korcsmaros+T%22">Korcsmaros T</searchLink>; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College, London, UK.; NIHR Imperial BRC Organoid Facility, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Talman+AM%22">Talman AM</searchLink>; MIVEGEC, University of Montpellier, IRD, CNRS, Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Frickel+EM%22">Frickel EM</searchLink>; Department of Microbiology and Molecular Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tate+EW%22">Tate EW</searchLink>; The Francis Crick Institute, London, UK.; Department of Chemistry, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Visweswariah+SS%22">Visweswariah SS</searchLink>; Department of Developmental Biology & Genetics, Indian Institute of Science, Bengaluru, India.; Department of Life Sciences, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Frankel+G%22">Frankel G</searchLink>; Department of Life Sciences, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Shenoy+AR%22">Shenoy AR</searchLink>; Department of Infectious Disease, Imperial College London, London, UK. a.shenoy@imperial.ac.uk.
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