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Peripheral and central immune features in insomnia: Integrative bulk and single-cell transcriptomic analyses reveal core hub genes and candidate compounds.

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Title: Peripheral and central immune features in insomnia: Integrative bulk and single-cell transcriptomic analyses reveal core hub genes and candidate compounds.
Authors: Zhu W; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China., Wen Z; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China., Gao Y; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China., He B; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China., Chen R; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China., Pan H; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China., Bin W; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China., Yang Z; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China. yangzhimin1966@gzucm.edu.cn.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China. yangzhimin1966@gzucm.edu.cn., Tan F; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China. tanfei2021@gzucm.edu.cn.
Source: Functional & integrative genomics [Funct Integr Genomics] 2026 Jun 10; Vol. 26 (1). Date of Electronic Publication: 2026 Jun 10.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Germany NLM ID: 100939343 Publication Model: Electronic Cited Medium: Internet ISSN: 1438-7948 (Electronic) Linking ISSN: 1438793X NLM ISO Abbreviation: Funct Integr Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Peripheral and central immune features in insomnia: Integrative bulk and single-cell transcriptomic analyses reveal core hub genes and candidate compounds.
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  Data: <searchLink fieldCode="AU" term="%22Zhu+W%22">Zhu W</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China.<br /><searchLink fieldCode="AU" term="%22Wen+Z%22">Wen Z</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China.<br /><searchLink fieldCode="AU" term="%22Gao+Y%22">Gao Y</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.<br /><searchLink fieldCode="AU" term="%22He+B%22">He B</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China.<br /><searchLink fieldCode="AU" term="%22Chen+R%22">Chen R</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China.<br /><searchLink fieldCode="AU" term="%22Pan+H%22">Pan H</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China.<br /><searchLink fieldCode="AU" term="%22Bin+W%22">Bin W</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China.<br /><searchLink fieldCode="AU" term="%22Yang+Z%22">Yang Z</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China. yangzhimin1966@gzucm.edu.cn.; Guangdong Laboratory of Chinese Medicine (Hengqin Laboratory), Hengqin, Guangdong Macao Deep Cooperation Zone, 519031, China. yangzhimin1966@gzucm.edu.cn.<br /><searchLink fieldCode="AU" term="%22Tan+F%22">Tan F</searchLink>; State Key Laboratory of Traditional Chinese Medicine Syndrome/The Second Clinical School, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, 510006, China. tanfei2021@gzucm.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22100939343%22">Functional & integrative genomics</searchLink> [Funct Integr Genomics] 2026 Jun 10; Vol. 26 (1). <i>Date of Electronic Publication: </i>2026 Jun 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>100939343 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1438-7948 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221438793X%22">1438793X </searchLink><i>NLM ISO Abbreviation: </i>Funct Integr Genomics <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun 10
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